《急診每日一題》降鈣素原在社區(qū)獲得性肺炎中的作用2021年8月
Question?問(wèn)題:
Procalcitonin can help differentiate viral from bacterial pathogens in patients admitted for Community Acquired Pneumonia. Typical bacteria result in higher PCT levels than atypical bacteria or viruses. Why? How reliable is PCT testing for CAP??
降鈣素原(PCT)有助于鑒別社區(qū)獲得性肺炎(CAP)是病毒性還是細(xì)菌性的。典型細(xì)菌感染PCT高于非典型細(xì)菌或病毒。為什么?PCT試驗(yàn)在CAP中可靠嗎?
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Answer?答案:
Cytokines, associated with bacterial infections, enhance PCT release, while interferons, associated with viral infections, inhibit PCT release. However, PCT will not be elevated in up to 23% of typical bacterial infections.?
與細(xì)菌感染相關(guān)的細(xì)胞因子增加PCT釋放,而與病毒相關(guān)感染卻抑制PCT釋放。但是,PCT在23%典型細(xì)菌感染中并不升高。
參考文獻(xiàn):
CCJM. Vol. 87:145
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