鈣離子載體 A23187 離子載體(鈣鎂鹽混合物)(Calcimycin)是一種來自沙特鏈霉菌的離子載體的聚醚抗生素。離子載體(鈣鎂鹽混合物)結(jié)合并運(yùn)輸鈣和其他二價(jià)陽離子穿過膜，并解耦氧化磷酸化，同時(shí)抑制大鼠肝線粒體的ATPase。離子載體(鈣鎂鹽混合物)主要用作生化工具，以研究二價(jià)陽離子在各種生物系統(tǒng)中的作用。

溶解度:Soluble in water (Partly miscible), DMSO (1 mg/ml), and DMF (10 mg/ml).

性狀 Solid power

儲(chǔ)藏條件:儲(chǔ)存溫度2-8℃

案例：

Calcium ionophore A23187-activated PMN release dsDNA more rapidly than PMA-activated PMN. PMN (2?×?105) were incubated in the presence or absence of increasing concentrations of PMA (A) or A23197 (B) for 240?min. The presence of extracellular dsDNA was detected at the indicated times with Sytox Green. Both graphs are representative of three identical experiments and show means?±?SEM of duplicate samples (C) Comparison of extracellular dsDNA levels 3?h after PMA or A23187 activation; data are means?±?SEM (n?=?3). AU, arbitrary units.