《急診每日一題》氟喹諾酮類抗生素與跟腱斷裂 2021年1月
Question 問(wèn)題:
Based upon current evidence, are fluoroquinolones as a class associated with increased risk of tendon rupture??
根據(jù)近期證據(jù),氟喹諾酮類抗生素有增加韌帶斷裂危險(xiǎn)嗎?
Answer 答案:
A recent study of prescription records of 1 million medicare patients found that FQ’s as a class were not associated with increased risk of tendon rupture. However, levofloxacin did exhibit significant increased risk。
一個(gè)近期對(duì)超過(guò)1百萬(wàn)醫(yī)療救助保險(xiǎn)患者的處方研究發(fā)現(xiàn),氟喹諾酮類總體上并沒(méi)有增加韌帶斷裂的危險(xiǎn)。但左氧氟沙星卻使其風(fēng)險(xiǎn)明顯增加。
參考文獻(xiàn):
BMJ Open, epub, 12/21/20
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