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【標題速讀】【Ncomm】【biological-sciences】【2022年】【9月】

2023-04-17 15:50 作者:Rt_Cola  | 我要投稿

聲明:本專欄主要對生命科學領域的一些期刊文章標題進行翻譯,所有內(nèi)容均由本人手工整理翻譯。由于本人專業(yè)為生物分析相關,其他領域如果出現(xiàn)翻譯錯誤請諒解。

1.Single cell and spatial transcriptomic analyses reveal microglia-plasma cell crosstalk in the brain during Trypanosoma brucei infection.

單細胞和空間轉(zhuǎn)錄組分析揭示了布氏錐蟲感染期間大腦中的小膠質(zhì)細胞-漿細胞串擾。

2.FtsN maintains active septal cell wall synthesis by forming a processive complex with the septum-specific peptidoglycan synthases in E. coli.

FtsN通過與大腸桿菌中的隔膜特異性肽聚糖合成酶形成漸進式復合物來維持活躍的隔膜細胞壁合成。

3.A transcriptional metastatic signature predicts survival in clear cell renal cell carcinoma.

轉(zhuǎn)錄轉(zhuǎn)移特征可預測透明細胞腎細胞癌的生存率。

4.Inositol hexakisphosphate is required for Integrator function.

肌醇六磷酸酯是整合者功能的必要條件。

5.ANGEL2 phosphatase activity is required for non-canonical mitochondrial RNA processing.

ANGEL2磷酸酶活性對非典范線粒體RNA加工是必需的。

6.Near-infrared phosphorescent carbon dots for sonodynamic precision tumor therapy.

近紅外磷光碳點用于聲動力精準腫瘤治療。

7.Effectiveness of COVID-19 vaccines against Omicron and Delta hospitalisation, a test negative case-control study.

COVID-19疫苗對Omicron和Delta住院的有效性,一項測試陰性的病例對照研究。

8.Lipid biosynthesis enzyme Agpat5 in AgRP-neurons is required for insulin-induced hypoglycemia sensing and glucagon secretion.

AgRP-神經(jīng)元中的脂質(zhì)生物合成酶Agpat5是胰島素誘導的低血糖感應和胰高血糖素分泌的必要條件。

9.Crowding results from optimal integration of visual targets with contextual information.

擁擠的結(jié)果是視覺目標與背景信息的最佳整合。

10.Household transmission of SARS-CoV-2 Omicron variant of concern subvariants BA.1 and BA.2 in Denmark.

丹麥SARS-CoV-2 Omicron變體關注亞變體BA.1和BA.2的家庭傳播。

11.A G358S mutation in the Plasmodium falciparum Na+ pump PfATP4 confers clinically-relevant resistance to cipargamin.

惡性瘧原蟲Na+泵PfATP4的G358S突變賦予了臨床相關的對西帕卡明的抗性。

12.Climate change may outpace current wheat breeding yield improvements in North America.

氣候變化可能超過目前北美地區(qū)小麥育種產(chǎn)量的提高。

13.Genomic analyses of rice bean landraces reveal adaptation and yield related loci to accelerate breeding.

稻豆陸地品種的基因組分析揭示了適應性和產(chǎn)量相關的位點,以加速育種。

14.A NAC-EXPANSIN module enhances maize kernel size by controlling nucellus elimination.

一個NAC-EXPANSIN模塊通過控制核仁的消除來增強玉米核仁的大小。

15.Genome-wide association study identifies a gene responsible for temperature-dependent rice germination.

全基因組關聯(lián)研究確定了一個負責溫度依賴性水稻發(fā)芽的基因。

16.Regain flood adaptation in rice through a 14-3-3 protein OsGF14h.

通過一個14-3-3蛋白OsGF14h重新恢復水稻的水災適應性。

17.Cost-effective methylome sequencing of cell-free DNA for accurately detecting and locating cancer.

成本效益高的無細胞DNA甲基組測序用于準確檢測和定位癌癥。

18.Exploration of nuclear body-enhanced sumoylation reveals that PML represses 2-cell features of embryonic stem cells.

探索核體增強的蘇木?;?,發(fā)現(xiàn)PML抑制胚胎干細胞的2細胞特征。

19.Deciphering microbial gene function using natural language processing.

利用自然語言處理破譯微生物基因功能。

20.Protein structural transitions critically transform the network connectivity and viscoelasticity of RNA-binding protein condensates but RNA can prevent it.

蛋白質(zhì)結(jié)構轉(zhuǎn)換關鍵性地改變了RNA結(jié)合蛋白凝集體的網(wǎng)絡連接和粘彈性,但RNA可以阻止它。

21.Adversarial attacks and adversarial robustness in computational pathology.

計算病理學中的對抗性攻擊和對抗性穩(wěn)健性。

22.Spatiotemporal organisation of protein processing in the kidney.

腎臟中蛋白質(zhì)加工的時空組織。

23.MYPT1-PP1β phosphatase negatively regulates both chromatin landscape and co-activator recruitment for beige adipogenesis.

MYPT1-PP1β磷酸酶同時負向調(diào)控染色質(zhì)景觀和共激活因子的招募以促進米色脂肪生成。

24.TM9SF4 is an F-actin disassembly factor that promotes tumor progression and metastasis.

TM9SF4是一種促進腫瘤進展和轉(zhuǎn)移的F-肌動蛋白分解因子。

25.Systematic identification of intron retention associated variants from massive publicly available transcriptome sequencing data.

從大量公開的轉(zhuǎn)錄組測序數(shù)據(jù)中系統(tǒng)識別內(nèi)含物保留相關變體。

26.Increased household transmission and immune escape of the SARS-CoV-2 Omicron compared to Delta variants.

與Delta變體相比,SARS-CoV-2 Omicron的家庭傳播和免疫逃逸增加。

27.SARS-CoV-2 infects adipose tissue in a fat depot- and viral lineage-dependent manner.

SARS-CoV-2以一種依賴脂肪庫和病毒系的方式感染脂肪組織。

28.Proteomic characterization of gastric cancer response to chemotherapy and targeted therapy reveals potential therapeutic strategies.

胃癌對化療和靶向治療反應的蛋白質(zhì)組學特征揭示了潛在的治療策略。

29.MicroRNA-7 regulates melanocortin circuits involved in mammalian energy homeostasis.

MicroRNA-7調(diào)控參與哺乳動物能量平衡的黑色皮質(zhì)素回路。

30.Bacteriophage-antibiotic combination therapy against extensively drug-resistant Pseudomonas aeruginosa infection to allow liver transplantation in a toddler.

噬菌體-抗生素聯(lián)合療法對抗廣泛耐藥的銅綠假單胞菌感染,讓幼兒進行肝移植。

31.A deeper understanding of system interactions can explain contradictory field results on pesticide impact on honey bees.

深入了解系統(tǒng)的相互作用可以解釋關于殺蟲劑對蜜蜂影響的矛盾的現(xiàn)場結(jié)果。

32.Experimental validation that human microbiome phages use alternative genetic coding.

實驗驗證了人類微生物組噬菌體使用替代基因編碼。

33.Interferon regulatory factor 1 (IRF-1) promotes intestinal group 3 innate lymphoid responses during Citrobacter rodentium infection.

干擾素調(diào)節(jié)因子1(IRF-1)在枸櫞酸桿菌感染期間促進腸道第3組先天淋巴反應。

34.Leveraging the science of stress to promote resilience and optimize mental health interventions during adolescence.

利用壓力科學促進復原力并優(yōu)化青少年時期的心理健康干預措施。

35.Multi-context genetic modeling of transcriptional regulation resolves novel disease loci.

轉(zhuǎn)錄調(diào)控的多背景遺傳模型解決了新的疾病位點。

36.A protein-based cGAS-STING nanoagonist enhances T cell-mediated anti-tumor immune responses.

一種基于蛋白質(zhì)的cGAS-STING納米拮抗劑增強了T細胞介導的抗腫瘤免疫反應。

37.Activation of the human insulin receptor by non-insulin-related peptides.

非胰島素相關肽對人類胰島素受體的激活作用。

38.The transcriptional coactivator RUVBL2 regulates Pol II clustering with diverse transcription factors.

轉(zhuǎn)錄輔助因子RUVBL2調(diào)控Pol II與不同轉(zhuǎn)錄因子的聚集。

39.In vivo self-assembled siRNA as a modality for combination therapy of ulcerative colitis.

體內(nèi)自組裝的siRNA作為潰瘍性結(jié)腸炎聯(lián)合治療的模式。

40.Lesion environments direct transplanted neural progenitors towards a wound repair astroglial phenotype in mice.

病變環(huán)境引導移植的神經(jīng)祖細胞向小鼠傷口修復星形膠質(zhì)表型發(fā)展。

41.Regional gene expression signatures are associated with sex-specific functional connectivity changes in depression.

區(qū)域基因表達特征與抑郁癥的性別特異性功能連接變化有關。

42.TFEB regulates sulfur amino acid and coenzyme A metabolism to support hepatic metabolic adaptation and redox homeostasis.

TFEB調(diào)節(jié)硫氨基酸和輔酶A的代謝以支持肝臟代謝適應和氧化還原平衡。

43.Structural basis for the activity regulation of a potassium channel AKT1 from Arabidopsis.

擬南芥鉀通道AKT1活性調(diào)節(jié)的結(jié)構基礎。

44.Combined IgE neutralization and Bifidobacterium longum supplementation reduces the allergic response in models of food allergy.

中和IgE和補充長雙歧桿菌聯(lián)合使用可降低食物過敏模型的過敏反應。

45.Phosphorylation of Jhd2 by the Ras-cAMP-PKA(Tpk2) pathway regulates histone modifications and autophagy.

Ras-cAMP-PKA(Tpk2)途徑對Jhd2的磷酸化調(diào)節(jié)組蛋白修飾和自噬。

46.Gene expression based inference of cancer drug sensitivity.

基于基因表達的癌癥藥物敏感性推斷。

47.Rejuvenation of the aged brain immune cell landscape in mice through p16-positive senescent cell clearance.

通過清除p16陽性的衰老細胞使小鼠大腦免疫細胞格局恢復活力。

48.The transcription factor Zfh1 acts as a wing-morph switch in planthoppers.

轉(zhuǎn)錄因子Zfh1作為翼形開關在刨花蟲中的作用。

49.Predicting the evolution of the Lassa virus endemic area and population at risk over the next decades.

預測未來幾十年拉薩病毒流行區(qū)和高危人群的演變。

50.TP53 mutations and RNA-binding protein MUSASHI-2 drive resistance to PRMT5-targeted therapy in B-cell lymphoma.

TP53突變和RNA結(jié)合蛋白MUSASHI-2驅(qū)動B細胞淋巴瘤對PRMT5靶向治療的抗性。

51.Hardship at birth alters the impact of climate change on a long-lived predator.

出生時的困難改變了氣候變化對一種長壽捕食者的影響。

52.Fatty acids homeostasis during fasting predicts protection from chemotherapy toxicity.

禁食期間的脂肪酸平衡預測了對化療毒性的保護。

53.Photocatalytic glucose depletion and hydrogen generation for diabetic wound healing.

光催化葡萄糖耗竭和氫氣生成促進糖尿病傷口愈合。

54.In situ small-angle X-ray scattering reveals strong condensation of DNA origami during silicification.

原位小角X射線散射揭示了硅化過程中DNA折紙的強烈凝結(jié)。

55.Zymoseptoria tritici white-collar complex integrates light, temperature and plant cues to initiate dimorphism and pathogenesis.

Zymoseptoria tritici白領復合體整合光、溫度和植物線索,啟動二形性和致病機制。

56.Genetic analysis of seed traits in Sorghum bicolor that affect the human gut microbiome.

影響人類腸道微生物組的雙色高粱種子性狀的遺傳分析。

57.The augmin complex architecture reveals structural insights into microtubule branching.

augmin復合體結(jié)構揭示了對微管分支的結(jié)構見解。

58.Circulating multimeric immune complexes contribute to immunopathology in COVID-19.

循環(huán)的多聚體免疫復合物有助于COVID-19的免疫病理學。

59.Modeling tissue-specific breakpoint proximity of structural variations from whole-genomes to identify cancer drivers.

從全基因組的結(jié)構變異中建立組織特異性斷點接近的模型,以確定癌癥驅(qū)動因素。

60.McaA and McaB control the dynamic positioning of a bacterial magnetic organelle.

McaA和McaB控制一個細菌磁性細胞器的動態(tài)定位。

61.High-throughput small molecule screen identifies inhibitors of microsporidia invasion and proliferation in C. elegans.

高通量小分子篩查確定了小孢子蟲入侵和增殖的抑制劑。

62.Classical center-surround receptive fields facilitate novel object detection in retinal bipolar cells.

經(jīng)典的中心-周圍感受區(qū)促進了視網(wǎng)膜雙極細胞的新物體檢測。

63.A Dilp8-dependent time window ensures tissue size adjustment in Drosophila.

依賴Dilp8的時間窗口確保果蠅的組織尺寸調(diào)整。

64.Predictive model for cytoneme guidance in Hedgehog signaling based on Ihog- Glypicans interaction.

基于Ihog-Glypicans相互作用的Hedgehog信號傳導中的細胞膜引導預測模型。

65.β-arrestin1 and 2 exhibit distinct phosphorylation-dependent conformations when coupling to the same GPCR in living cells.

β-arrestin1和2在活細胞中與同一GPCR偶聯(lián)時表現(xiàn)出不同的磷酸化依賴性構象。

66.Center-surround interactions underlie bipolar cell motion sensitivity in the mouse retina.

中心-周圍相互作用是小鼠視網(wǎng)膜雙極細胞運動敏感性的基礎。

67.A neuro-computational account of procrastination behavior.

拖延行為的神經(jīng)-計算學解釋。

68.TraB family proteins are components of ER-mitochondrial contact sites and regulate ER-mitochondrial interactions and mitophagy.

TraB家族蛋白是ER-mitochondrial接觸點的組成部分,調(diào)節(jié)ER-mitochondrial的相互作用和mitophagy。

69.The material properties of a bacterial-derived biomolecular condensate tune biological function in natural and synthetic systems.

細菌衍生的生物分子凝結(jié)物的材料特性在自然和合成系統(tǒng)中調(diào)控生物功能。

70.RAS oncogenic activity predicts response to chemotherapy and outcome in lung adenocarcinoma.

RAS致癌活性可預測肺腺癌的化療反應和結(jié)果。

71.Structural insights into molecular mechanism for N6-adenosine methylation by MT-A70 family methyltransferase METTL4.

對MT-A70家族甲基轉(zhuǎn)移酶METTL4的N6-腺苷甲基化的分子機制的結(jié)構見解。

72.Airway basal cells show a dedifferentiated KRT17highPhenotype and promote fibrosis in idiopathic pulmonary fibrosis.

氣道基底細胞顯示出去分化的KRT17highPhenotype并促進特發(fā)性肺纖維化的纖維化。

73.Single cell atlas of spinal cord injury in mice reveals a pro-regenerative signature in spinocerebellar neurons.

小鼠脊髓損傷的單細胞圖譜顯示了脊髓小腦神經(jīng)元的促再生特征。

74.Nocturnal plant respiration is under strong non-temperature control.

夜間植物的呼吸受到強烈的非溫度控制。

75.Graphdiyne oxide nanosheets display selective anti-leukemia efficacy against DNMT3A-mutant AML cells.

氧化石墨烯納米片對DNMT3A突變型AML細胞顯示出選擇性的抗白血病功效。

76.Redβ177 annealase structure reveals details of oligomerization and λ Red-mediated homologous DNA recombination.

Redβ177退火酶結(jié)構揭示了低聚物化和λ紅介導的同源DNA重組的細節(jié)。

77.USP14 promotes tryptophan metabolism and immune suppression by stabilizing IDO1 in colorectal cancer.

USP14通過穩(wěn)定結(jié)直腸癌的IDO1促進色氨酸代謝和免疫抑制。

78.The comparison of cancer gene mutation frequencies in Chinese and U.S. patient populations.

中國和美國患者群體中癌癥基因突變頻率的比較.

79.Two modes of evolution shape bacterial strain diversity in the mammalian gut for thousands of generations.

兩種進化模式塑造了哺乳動物腸道內(nèi)數(shù)千代的細菌菌株多樣性。

80.High-resolution silkworm pan-genome provides genetic insights into artificial selection and ecological adaptation.

高分辨率的家蠶泛基因組為人工選擇和生態(tài)適應提供了遺傳學方面的見解。

81.Tail proteins of phage SU10 reorganize into the nozzle for genome delivery.

噬菌體SU10的尾部蛋白重組到用于基因組輸送的噴嘴。

82.A miniaturized bionic ocean-battery mimicking the structure of marine microbial ecosystems.

模仿海洋微生物生態(tài)系統(tǒng)結(jié)構的小型仿生海洋電池。

83.Phosphorylcholine-conjugated gold-molecular clusters improve signal for Lymph Node NIR-II fluorescence imaging in preclinical cancer models.

磷酰膽堿結(jié)合的金分子簇改善了臨床前癌癥模型中淋巴結(jié)NIR-II熒光成像的信號。

84.Experimental evidence for core-Merge in the vocal communication system of a wild passerine.

野生過山鳥發(fā)聲通訊系統(tǒng)中核心合并的實驗證據(jù)。

85.Genomic and biological study of fusion genes as resistance mechanisms to EGFR inhibitors.

融合基因作為EGFR抑制劑抗性機制的基因組學和生物學研究。

86.Human centromere repositioning activates transcription and opens chromatin fibre structure.

人類中心粒的重新定位激活了轉(zhuǎn)錄并打開了染色質(zhì)纖維結(jié)構。

87.Comprehensive assessment of miniature CRISPR-Cas12f nucleases for gene disruption.

用于基因破壞的微型CRISPR-Cas12f核酸酶的綜合評估。

88.Structure of the malaria vaccine candidate Pfs48/45 and its recognition by transmission blocking antibodies.

瘧疾候選疫苗Pfs48/45的結(jié)構及其被傳播阻斷抗體的識別。

89.Lactobacillus supports Clostridiales to restrict gut colonization by multidrug-resistant Enterobacteriaceae.

乳酸菌支持梭狀芽孢桿菌限制耐多藥腸桿菌的腸道定植。

90.Synthetic neuromorphic computing in living cells.

活細胞中的合成神經(jīng)形態(tài)計算。

91.DNA methylation signatures of Alzheimer’s disease neuropathology in the cortex are primarily driven by variation in non-neuronal cell-types.

阿爾茨海默病神經(jīng)病理學的DNA甲基化特征主要由非神經(jīng)元細胞類型的變異驅(qū)動。

92.Interferon gamma mediates the reduction of adipose tissue regulatory T cells in human obesity.

γ干擾素介導了人類肥胖癥中脂肪組織調(diào)節(jié)性T細胞的減少。

93.Revisiting life history and morphological proxies for early mammaliaform metabolic rates.

重新審視早期哺乳動物形態(tài)代謝率的生活史和形態(tài)學代用指標。

94.Live imaging and conditional disruption of native PCP activity using endogenously tagged zebrafish sfGFP-Vangl2.

使用內(nèi)源性標記的斑馬魚sfGFP-Vangl2的活體成像和條件性破壞本地PCP活動。

95.The evolutionary advantage of an aromatic clamp in plant family 3 glycoside exo-hydrolases.

植物第3家族糖類外水解酶中芳香族鉗的進化優(yōu)勢。

96.Accumulation of mutations in antibody and CD8 T cell epitopes in a B cell depleted lymphoma patient with chronic SARS-CoV-2 infection.

慢性SARS-CoV-2感染的B細胞耗竭型淋巴瘤患者的抗體和CD8 T細胞表位突變的積累。

97.Reply to: Relationship of circulating Plasmodium falciparum lifecycle stage to circulating parasitemia and total parasite biomass.

Reply to:?循環(huán)惡性瘧原蟲生命周期階段與循環(huán)寄生蟲血癥和寄生蟲總生物量的關系。

98.Intracellular energy controls dynamics of stress-induced ribonucleoprotein granules.

細胞內(nèi)能量控制壓力誘導的核糖核蛋白顆粒的動力學。

99.Relationship of circulating Plasmodium falciparum lifecycle stage to circulating parasitemia and total parasite biomass.

惡性瘧原蟲生命周期階段與循環(huán)寄生蟲血癥和總寄生蟲生物量的關系。

100.Reply to: Revisiting life history and morphological proxies for early mammaliaform metabolic rates.

Reply to:?重新審視早期哺乳動物形態(tài)代謝率的生活史和形態(tài)學代用指標。

101.Using multiple sampling strategies to estimate SARS-CoV-2 epidemiological parameters from genomic sequencing data.

使用多種采樣策略從基因組測序數(shù)據(jù)中估計SARS-CoV-2的流行病學參數(shù)。

102.Cytoplasmic organization promotes protein diffusion in Xenopus extracts.

細胞質(zhì)組織促進蛋白質(zhì)在Xenopus提取物中的擴散。

103.Bacterial diet modulates tamoxifen-induced death via host fatty acid metabolism.

細菌飲食通過宿主脂肪酸代謝調(diào)控他莫西芬誘導的死亡。

104.CNS myelination requires VAMP2/3-mediated membrane expansion in oligodendrocytes.

中樞神經(jīng)系統(tǒng)髓鞘化需要VAMP2/3介導的少突膠質(zhì)細胞膜擴張。

105.Activation of the insulin receptor by an insulin mimetic peptide.

胰島素模擬肽對胰島素受體的激活.

106.Activation of stably silenced genes by recruitment of a synthetic de-methylating module.

通過招募合成去甲基化模塊激活穩(wěn)定沉默的基因。

107.Local features drive identity responses in macaque anterior face patches.

局部特征驅(qū)動獼猴前臉斑塊的身份反應。

108.An online atlas of human plasma metabolite signatures of gut microbiome composition.

腸道微生物組組成的人類血漿代謝物特征的在線圖譜。

109.Synaptic plasticity in self-powered artificial striate cortex for binocular orientation selectivity.

自力更生的人工紋狀皮層的突觸可塑性對雙眼方向的選擇性。

110.Household transmission of the SARS-CoV-2 Omicron variant in Denmark.

SARS-CoV-2 Omicron變體在丹麥的家庭傳播。

111.Protein condensation diseases: therapeutic opportunities.

蛋白質(zhì)凝結(jié)疾?。褐委煓C會。

112.A fungal tolerance trait and selective inhibitors proffer HMG-CoA reductase as a herbicide mode-of-action.

一種真菌耐受性特征和選擇性抑制劑提供了HMG-CoA還原酶作為除草劑的作用方式。

113.Engineering SARS-CoV-2 specific cocktail antibodies into a bispecific format improves neutralizing potency and breadth.

將SARS-CoV-2特異性雞尾酒抗體工程化為雙特異性格式,提高中和效力和廣度。

114.Wireless multi-lateral optofluidic microsystems for real-time programmable optogenetics and photopharmacology.

用于實時可編程光遺傳學和光藥學的無線多側(cè)光流體微系統(tǒng)。

115.IL-23 signaling prevents ferroptosis-driven renal immunopathology during candidiasis.

IL-23信號防止念珠菌病期間鐵蛋白驅(qū)動的腎臟免疫病理學。

116.High-throughput mutagenesis identifies mutations and RNA-binding proteins controlling CD19 splicing and CART-19 therapy resistance.

高通量誘變確定了控制CD19剪接和CART-19療法抗性的突變和RNA結(jié)合蛋白。

117.Endocytosis-like DNA uptake by cell wall-deficient bacteria.

細胞壁缺損的細菌對DNA的內(nèi)吞作用。

118.Chromatin organizer SATB1 controls the cell identity of CD4+ CD8+ double-positive thymocytes by regulating the activity of super-enhancers.

染色質(zhì)組織者SATB1通過調(diào)控超級增強子的活性控制CD4+CD8+雙陽性胸腺細胞的細胞身份。

119.Tracking changes in SARS-CoV-2 transmission with a novel outpatient sentinel surveillance system in Chicago, USA.

利用美國芝加哥的新型門診哨點監(jiān)測系統(tǒng)追蹤SARS-CoV-2傳播的變化。

120.Context-dependent selectivity to natural images in the retina.

視網(wǎng)膜中對自然圖像的語境依賴性選擇。

121.Ubiquitination of CLIP-170 family protein restrains polarized growth upon DNA replication stress.

CLIP-170家族蛋白的泛質(zhì)化抑制了DNA復制壓力下的極化生長。

122.Topical application of an irreversible small molecule inhibitor of lysyl oxidases ameliorates skin scarring and fibrosis.

一種不可逆的小分子賴氨酸氧化酶抑制劑的局部應用可改善皮膚瘢痕和纖維化。

123.VAL1 acts as an assembly platform co-ordinating co-transcriptional repression and chromatin regulation at Arabidopsis FLC.

VAL1作為組裝平臺,協(xié)調(diào)擬南芥FLC的共轉(zhuǎn)錄抑制和染色質(zhì)調(diào)節(jié)。

124.Neural probe system for behavioral neuropharmacology by bi-directional wireless drug delivery and electrophysiology in socially interacting mice.

通過雙向無線給藥和社會互動小鼠的電生理學,用于行為神經(jīng)藥理學的神經(jīng)探測系統(tǒng)。

125.The SARS-CoV-2 Omicron BA.1 spike G446S mutation potentiates antiviral T-cell recognition.

SARS-CoV-2 Omicron BA.1穗狀體G446S突變增強了抗病毒T細胞識別能力。

126.Differential dysregulation of granule subsets in WASH-deficient neutrophil leukocytes resulting in inflammation.

WASH缺陷的中性粒細胞白細胞中顆粒亞群的差異性失調(diào)導致炎癥的發(fā)生。

127.Magnitude of venous or capillary blood-derived SARS-CoV-2-specific T cell response determines COVID-19 immunity.

靜脈或毛細血管血源的SARS-CoV-2特異性T細胞反應的大小決定了COVID-19的免疫力。

128.Evolutionary origin of vertebrate OCT4/POU5 functions in supporting pluripotency.

脊椎動物OCT4/POU5支持多能性功能的進化起源。

129.Multi-omic brain and behavioral correlates of cell-free fetal DNA methylation in macaque maternal obesity models.

獼猴母體肥胖模型中無細胞胎兒DNA甲基化的多組腦和行為相關性。

130.Metabolic pathway assembly using docking domains from type I cis-AT polyketide synthases.

利用I型順式AT聚酮體合成酶的對接域進行代謝途徑組裝。

131.Insular cortical circuits as an executive gateway to decipher threat or extinction memory via distinct subcortical pathways.

島狀皮層回路作為執(zhí)行通道,通過不同的皮層下途徑破譯威脅或消亡記憶。

132.Leaf water content contributes to global leaf trait relationships.

葉子含水量對全球葉子性狀關系的貢獻。

133.Transcriptomic architecture of nuclei in the marmoset CNS.

狨猴中樞神經(jīng)系統(tǒng)核的轉(zhuǎn)錄組結(jié)構。

134.Reaction-based fluorogenic probes for detecting protein cysteine oxidation in living cells.

基于反應的熒光探針用于檢測活細胞中蛋白質(zhì)半胱氨酸的氧化。

135.A de novo matrix for macroscopic living materials from bacteria.

來自細菌的宏觀活體材料的脫胎換骨矩陣。

136.Intrinsic bias estimation for improved analysis of bulk and single-cell chromatin accessibility profiles using SELMA.

使用SELMA改進批量和單細胞染色質(zhì)可及性分析的內(nèi)在偏差估計。

137.Resolving molecular diffusion and aggregation of antibody proteins with megahertz X-ray free-electron laser pulses.

用兆赫X射線自由電子激光脈沖解析抗體蛋白的分子擴散和聚集。

138.Preclinical and randomized clinical evaluation of the p38α kinase inhibitor neflamapimod for basal forebrain cholinergic degeneration.

p38α激酶抑制劑neflamapimod治療基底前腦膽堿能退化的臨床前和隨機臨床評估。

139.Adar-mediated A-to-I editing is required for embryonic patterning and innate immune response regulation in zebrafish.

Adar?介導的?A-to-I?編輯是斑馬魚胚胎模式和先天免疫反應調(diào)節(jié)所必需的。

140.QuasAr Odyssey: the origin of fluorescence and its voltage sensitivity in microbial rhodopsins.

QuasAr Odyssey:?熒光的起源及其在微生物荷爾蒙蛋白中的電壓敏感性。

141.Screening microbially produced Δ9-tetrahydrocannabinol using a yeast biosensor workflow.

使用酵母生物傳感器工作流程篩選微生物生產(chǎn)的Δ9-四氫大麻酚。

142.Learning enhances encoding of time and temporal surprise in mouse primary sensory cortex.

學習增強了小鼠初級感覺皮層中時間和時間性驚喜的編碼。

143.Systematic profiling of conditional degron tag technologies for target validation studies.

用于目標驗證研究的條件性degron標簽技術的系統(tǒng)剖析。

144.Insight into mode-of-action and structural determinants of the compstatin family of clinical complement inhibitors.

洞察臨床補體抑制劑compstatin家族的作用方式和結(jié)構決定因素。

145.Deciphering multi-way interactions in the human genome.

解讀人類基因組中的多向互動。

146.The AAA+ ATPase RavA and its binding partner ViaA modulate E. coli aminoglycoside sensitivity through interaction with the inner membrane.

AAA+ATP酶RavA及其結(jié)合伙伴ViaA通過與內(nèi)膜的相互作用調(diào)節(jié)大腸桿菌氨基糖苷的敏感性。

147.Small soluble α-synuclein aggregates are the toxic species in Parkinson’s disease.

小的可溶性α-synuclein聚集物是帕金森病的毒性物種。

148.Single cell atlas identifies lipid-processing and immunomodulatory endothelial cells in healthy and malignant breast.

單細胞圖譜識別健康和惡性乳腺中的脂質(zhì)處理和免疫調(diào)節(jié)內(nèi)皮細胞。

149.Structure of the PAPP-ABP5 complex reveals mechanism of substrate recognition.

PAPP-ABP5復合物的結(jié)構揭示了底物識別的機制。

150.An anti-inflammatory activation sequence governs macrophage transcriptional dynamics during tissue injury in zebrafish.

斑馬魚組織損傷期間抗炎激活序列支配巨噬細胞的轉(zhuǎn)錄動態(tài)。

151.Smart soft contact lenses for continuous 24-hour monitoring of intraocular pressure in glaucoma care.

用于青光眼護理中24小時連續(xù)監(jiān)測眼壓的智能軟性隱形眼鏡。

152.DNA methylation as a pharmacodynamic marker of glucocorticoid response and glioma survival.

DNA甲基化作為糖皮質(zhì)激素反應和膠質(zhì)瘤生存的藥效學標志。

153.Structural basis of adhesion GPCR GPR110 activation by stalk peptide and G-proteins coupling.

粘附性GPCR GPR110被柄肽和G-蛋白質(zhì)偶聯(lián)激活的結(jié)構基礎。

154.An EGFR/HER2-targeted conjugate sensitizes gemcitabine-sensitive and resistant pancreatic cancer through different SMAD4-mediated mechanisms.

一種EGFR/HER2靶向共軛物通過不同的SMAD4介導的機制使吉西他濱敏感和耐藥的胰腺癌致敏。

155.Flexible cue anchoring strategies enable stable head direction coding in both sighted and blind animals.

靈活的線索錨定策略使有視力和失明動物的頭部方向編碼穩(wěn)定。

156.A stem cell roadmap of ribosome heterogeneity reveals a function for RPL10A in mesoderm production.

核糖體異質(zhì)性的干細胞路線圖揭示了RPL10A在中胚層生產(chǎn)中的功能。

157.Structural characterization of a soil viral auxiliary metabolic gene product – a functional chitosanase.

土壤病毒輔助代謝基因產(chǎn)品的結(jié)構特征--一種功能性殼聚糖酶。

158.Angiocrine extracellular vesicles impose mesenchymal reprogramming upon proneural glioma stem cells.

血管內(nèi)分泌胞外小泡對原神經(jīng)膠質(zhì)瘤干細胞施加間質(zhì)重編程。

159.Extracellular fibrinogen-binding protein released by intracellular Staphylococcus aureus suppresses host immunity by targeting TRAF3.

細胞內(nèi)金黃色葡萄球菌釋放的細胞外纖維蛋白原結(jié)合蛋白通過靶向TRAF3抑制宿主免疫力。

160.Biosynthesis of plant hemostatic dencichine in Escherichia coli.

大腸桿菌中植物止血劑dencichine的生物合成。

161.Modeling human HSV infection via a vascularized immune-competent skin-on-chip platform.

通過一個血管化的免疫能力皮膚芯片平臺模擬人類HSV感染。

162.Mutated processes predict immune checkpoint inhibitor therapy benefit in metastatic melanoma.

突變過程預測免疫檢查點抑制劑治療轉(zhuǎn)移性黑色素瘤的益處。

163.Transformation of primary sensory cortical representations from layer 4 to layer 2.

初級感覺皮質(zhì)表征從第4層到第2層的轉(zhuǎn)變。

164.Integrated stem cell signature and cytomolecular risk determination in pediatric acute myeloid leukemia.

小兒急性骨髓性白血病的綜合干細胞特征和細胞分子風險判斷。

165.Dominant role of DNA methylation over H3K9me3 for IAP silencing in endoderm.

DNA甲基化超過H3K9me3對內(nèi)胚層IAP沉默的主導作用。

166.Causal contribution of optic flow signal in Macaque extrastriate visual cortex for roll perception.

獼猴視外皮層中視流信號對滾動感知的因果貢獻。

167.ARID1A mutations confer intrinsic and acquired resistance to cetuximab treatment in colorectal cancer.

ARID1A突變賦予結(jié)直腸癌對西妥昔單抗治療的內(nèi)在和獲得性抵抗。

168.Stress induced TDP-43 mobility loss independent of stress granules.

應激誘導的TDP-43移動性喪失與應激顆粒無關。

169.Identification of spatially variable genes with graph cuts.

用圖形切割識別空間可變基因。

170.The effect of carbon fertilization on naturally regenerated and planted US forests.

碳肥對美國自然再生林和人工林的影響.

171.Quantitative fragmentomics allow affinity mapping of interactomes.

定量片段組學允許親和地繪制交互組圖。

172.A self-assembled trimeric protein vaccine induces protective immunity against Omicron variant.

一種自組裝的三聚體蛋白疫苗誘導了對Omicron變體的保護性免疫力。

173.Phylogeographic analysis reveals an ancient East African origin of human herpes simplex virus 2 dispersal out-of-Africa.

系統(tǒng)地理學分析揭示了人類單純皰疹病毒2在非洲以外地區(qū)傳播的古老東非起源。

174.Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation.

tapasin介導的MHC-I肽在抗原表達中的結(jié)構機制。

175.Spatio-temporal analysis of prostate tumors in situ suggests pre-existence of treatment-resistant clones.

前列腺原位腫瘤的時空分析表明治療抗性克隆的預先存在。

176.Mechanistic understanding of human SLFN11.

對人類SLFN11的機制理解。

177.The immune landscape of human thymic epithelial tumors.

人類胸腺上皮細胞腫瘤的免疫景觀。

178.Single-cell transcriptomics reveal cellular diversity of aortic valve and the immunomodulation by PPARγ during hyperlipidemia.

單細胞轉(zhuǎn)錄組學揭示了主動脈瓣的細胞多樣性和高脂血癥時PPARγ的免疫調(diào)節(jié)作用。

179.A randomized controlled trial of heterologous ChAdOx1 nCoV-19 and recombinant subunit vaccine MVC-COV1901 against COVID-19.

異源ChAdOx1 nCoV-19和重組亞單位疫苗MVC-COV1901對抗COVID-19的隨機對照試驗。

180.Oncogenic RAS commandeers amino acid sensing machinery to aberrantly activate mTORC1 in multiple myeloma.

致癌性RAS征用氨基酸感應機制異常激活多發(fā)性骨髓瘤的mTORC1。

181.Infralimbic medial prefrontal cortex signalling to calbindin 1 positive neurons in posterior basolateral amygdala suppresses anxiety- and depression-like behaviours.

下肢內(nèi)側(cè)前額葉皮層對后基底外側(cè)杏仁核中calbindin 1陽性神經(jīng)元的信號傳遞抑制了焦慮和抑郁樣行為。

182.Imprinting fidelity in mouse iPSCs depends on sex of donor cell and medium formulation.

小鼠iPSCs的印記保真度取決于供體細胞的性別和培養(yǎng)基配方。

183.A multi-adenylate cyclase regulator at the flagellar tip controls African trypanosome transmission.

鞭毛頂端的多腺苷酸環(huán)化酶調(diào)節(jié)器控制非洲錐蟲的傳播。

184.A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II.

SMN的一個小分子拮抗劑破壞了SMN和RNAP II之間的相互作用。

185.Molecular architecture of the augmin complex.

augmin復合物的分子結(jié)構。

186.Structural insights into the pSer/pThr dependent regulation of the SHP2 tyrosine phosphatase in insulin and CD28 signaling.

對胰島素和CD28信號中SHP2酪氨酸磷酸酶的pSer/pThr依賴性調(diào)控的結(jié)構見解。

187.Structure-based discovery of small molecules that disaggregate Alzheimer’s disease tissue derived tau fibrils in vitro.

基于結(jié)構發(fā)現(xiàn)體外分解阿爾茨海默病組織衍生的tau纖維的小分子。

188.Electrostatic and steric effects underlie acetylation-induced changes in ubiquitin structure and function.

靜電和立體效應是乙?;鸬姆核亟Y(jié)構和功能變化的基礎。

189.Clustering by measuring local direction centrality for data with heterogeneous density and weak connectivity.

通過測量具有異質(zhì)密度和弱連接性的數(shù)據(jù)的局部方向中心性進行聚類。

190.Serum neutralization activity declines but memory B cells persist after cure of chronic hepatitis C.

慢性丙型肝炎治愈后血清中和活性下降但記憶B細胞持續(xù)存在。

191.Unleashing the potential of noncanonical amino acid biosynthesis to create cells with precision tyrosine sulfation.

釋放非經(jīng)典氨基酸生物合成的潛力,創(chuàng)造具有精確酪氨酸硫酸化的細胞。

192.WRN promotes bone development and growth by unwinding SHOX-G-quadruplexes via its helicase activity in Werner Syndrome.

Werner綜合征中WRN通過其螺旋酶活性解開SHOX-G-四聯(lián)體,促進骨骼發(fā)育和生長。

193.A temporal sequence of thalamic activity unfolds at transitions in behavioral arousal state.

丘腦活動的時間序列在行為喚醒狀態(tài)的轉(zhuǎn)換中展開。

194.Structures reveal a key mechanism of WAVE regulatory complex activation by Rac1 GTPase.

結(jié)構揭示了Rac1 GTP酶激活WAVE調(diào)節(jié)復合物的關鍵機制。

195.Conserved features of TERT promoter duplications reveal an activation mechanism that mimics hotspot mutations in cancer.

TERT啟動子復制的保守特征揭示了一種模仿癌癥熱點突變的激活機制。

196.Water regulates the residence time of Benzamidine in Trypsin.

水調(diào)控苯甲脒在胰蛋白酶中的停留時間。

197.Efficient and accurate frailty model approach for genome-wide survival association analysis in large-scale biobanks.

用于大規(guī)模生物庫中全基因組生存關聯(lián)分析的高效準確的虛弱度模型方法。

198.Enzymatic synthesis of benzylisoquinoline alkaloids using a parallel cascade strategy and tyrosinase variants.

使用平行級聯(lián)策略和酪氨酸酶變體的芐基異喹啉生物堿的酶促合成。

199.Pangenomic analysis of Chinese gastric cancer.

中國胃癌的Pangenomic分析.

200.Batch effects removal for microbiome data via conditional quantile regression.

通過條件量化回歸去除微生物組數(shù)據(jù)的批處理效應.

201.Liver group 2 innate lymphoid cells regulate blood glucose levels through IL-13 signaling and suppression of gluconeogenesis.

肝臟第2組先天性淋巴細胞通過IL-13信號傳導和抑制葡萄糖生成來調(diào)節(jié)血糖水平。

202.Murine fetal bone marrow does not support functional hematopoietic stem and progenitor cells until birth.

小鼠胎兒骨髓在出生前不支持功能性造血干細胞和祖細胞。

203.Cryptococcal Hsf3 controls intramitochondrial ROS homeostasis by regulating the respiratory process.

隱球菌Hsf3通過調(diào)控呼吸過程控制線粒體內(nèi)ROS平衡。

204.Transcriptional profiling of matched patient biopsies clarifies molecular determinants of enzalutamide-induced lineage plasticity.

匹配患者活體組織的轉(zhuǎn)錄分析闡明了恩扎魯胺誘導的血統(tǒng)可塑性的分子決定因素。

205.Structure of the active Gi-coupled human lysophosphatidic acid receptor 1 complexed with a potent agonist.

活躍的Gi偶聯(lián)人類溶血磷脂酸受體1與強效激動劑復合的結(jié)構。

206.Transcriptional dynamics of murine motor neuron maturation in vivo and in vitro.

小鼠運動神經(jīng)元在體內(nèi)和體外成熟時的轉(zhuǎn)錄動態(tài)。

207.The complement C3-complement factor D-C3a receptor signalling axis regulates cardiac remodelling in right ventricular failure.

補體C3-補體因子D-C3a受體信號軸調(diào)節(jié)右心室衰竭的心臟重塑。

208.Sirtuin 6 inhibition protects against glucocorticoid-induced skeletal muscle atrophy by regulating IGF/PI3K/AKT signaling.

抑制Sirtuin 6通過調(diào)節(jié)IGF/PI3K/AKT信號來保護糖皮質(zhì)激素引起的骨骼肌萎縮。

209.Reconstitution of microtubule into GTP-responsive nanocapsules.

將微管重組為GTP反應型納米膠囊。

210.Inhibition of UBA6 by inosine augments tumour immunogenicity and responses.

肌苷對UBA6的抑制增強了腫瘤的免疫原性和反應。

211.Cancer co-opts differentiation of B-cell precursors into macrophage-like cells.

癌癥共同決定了B細胞前體向巨噬細胞的分化。

212.Streptococcus agalactiae cadD alleviates metal stress and promotes intracellular survival in macrophages and ascending infection during pregnancy.

agalactiae鏈球菌cadD減輕金屬壓力,促進巨噬細胞的細胞內(nèi)生存和懷孕期間的上升感染。

213.Structure of the membrane-bound formate hydrogenlyase complex from Escherichia coli.

大腸桿菌的膜結(jié)合型甲酸氫酶復合物的結(jié)構。

214.A blind benchmark of analysis tools to infer kinetic rate constants from single-molecule FRET trajectories.

從單分子FRET軌跡推斷動力學速率常數(shù)的分析工具的盲測基準。

215.The clinical drug candidate anle138b binds in a cavity of lipidic α-synuclein fibrils.

臨床候選藥物anle138b在脂質(zhì)α-synuclein纖維的空腔中結(jié)合。

216.Layered feedback control overcomes performance trade-off in synthetic biomolecular networks.

分層反饋控制克服了合成生物分子網(wǎng)絡中的性能折衷問題。

217.Optogenetic control of apical constriction induces synthetic morphogenesis in mammalian tissues.

光遺傳控制頂端收縮誘導了哺乳動物組織的合成形態(tài)發(fā)生。

218.Multiple parameters shape the 3D chromatin structure of single nuclei at the doc locus in Drosophila.

多個參數(shù)塑造了果蠅doc基因座上單個核的三維染色質(zhì)結(jié)構。

219.Structure of an MHC I–tapasin–ERp57 editing complex defines chaperone promiscuity.

MHC I-tapasin-ERp57編輯復合物的結(jié)構確定了伴侶的雜亂性。

220.Telomere-to-telomere genome sequence of the model mould pathogen Aspergillus fumigatus.

模型霉菌病原體曲霉的端粒到端粒的基因組序列。

221.Structural basis for APE1 processing DNA damage in the nucleosome.

APE1處理核糖體中DNA損傷的結(jié)構基礎。

222.Epigenetic activation of the FLT3 gene by ZNF384 fusion confers a therapeutic susceptibility in acute lymphoblastic leukemia.

ZNF384融合對FLT3基因的表觀遺傳激活賦予急性淋巴細胞白血病的治療易感性。

223.In situ analysis of nanoparticle soft corona and dynamic evolution.

納米粒子軟冕的原位分析和動態(tài)演變。

224.Assembly of transmembrane pores from mirror-image peptides.

鏡像肽的跨膜孔的組裝。

225.Effects of biological sex mismatch on neural progenitor cell transplantation for spinal cord injury in mice.

生物性別錯配對神經(jīng)祖細胞移植治療小鼠脊髓損傷的影響。

226.Mettl3-dependent m6A modification attenuates the brain stress response in Drosophila.

Mettl3依賴的m6A修飾減弱了果蠅的大腦應激反應。

227.Mild dyslipidemia accelerates tumorigenesis through expansion of Ly6Chi monocytes and differentiation to pro-angiogenic myeloid cells.

輕度血脂異常通過擴張Ly6Chi單核細胞和分化為促血管生成的骨髓細胞加速了腫瘤的發(fā)生。

228.Paternal imprinting of dosage-effect defective1 contributes to seed weight xenia in maize.

劑量效應缺陷1的父系印記有助于玉米的種子重量異位。

229.Fatty acid metabolism in aggressive B-cell lymphoma is inhibited by tetraspanin CD37.

侵襲性B細胞淋巴瘤中的脂肪酸代謝被四泛素CD37所抑制。

230.Diverse cell-specific patterns of alternative polyadenylation in Drosophila.

果蠅替代性聚腺苷酸化的不同細胞特異性模式。

231.Interleukin-1 contributes to clonal expansion and progression of bone marrow fibrosis in JAK2V617F-induced myeloproliferative neoplasm.

白細胞介素-1有助于JAK2V617F誘導的骨髓增生性腫瘤中的克隆擴展和骨髓纖維化的進展。

232.Inhibition of interleukin-1β reduces myelofibrosis and osteosclerosis in mice with JAK2-V617F driven myeloproliferative neoplasm.

抑制白細胞介素-1β可以減少JAK2-V617F驅(qū)動的骨髓增生性腫瘤小鼠的骨髓纖維化和骨質(zhì)硬化。

233.Machine-learning prediction of hosts of novel coronaviruses requires caution as it may affect wildlife conservation.

對新型冠狀病毒宿主的機器學習預測需要謹慎,因為它可能影響野生動物的保護。

234.Reply to: Machine-learning prediction of hosts of novel coronaviruses requires caution as it may affect wildlife conservation.

回應:?機器學習預測新型冠狀病毒的宿主需要謹慎,因為它可能會影響野生動物的保護。

235.The importance of antimicrobial resistance in medical mycology.

醫(yī)學真菌學中抗菌素抗性的重要性。

236.Improved immunoassay sensitivity and specificity using single-molecule colocalization.

利用單分子共聚焦技術提高免疫測定的靈敏度和特異性。

237.GCAF(TMEM251) regulates lysosome biogenesis by activating the mannose-6-phosphate pathway.

GCAF(TMEM251)通過激活甘露糖-6-磷酸途徑調(diào)控溶酶體生物生成。

238.Genomic insights into rapid speciation within the world’s largest tree genus Syzygium.

對世界上最大的樹種Syzygium屬的快速物種形成的基因組學見解。

239.SREBP2-dependent lipid gene transcription enhances the infection of human dendritic cells by Zika virus.

SREBP2依賴的脂質(zhì)基因轉(zhuǎn)錄增強了寨卡病毒對人類樹突狀細胞的感染。

240.Robust data storage in DNA by de Bruijn graph-based de novo strand assembly.

基于de Bruijn圖的新鏈組裝在DNA中的穩(wěn)健數(shù)據(jù)存儲。

241.Identification of a binding site on soluble RANKL that can be targeted to inhibit soluble RANK-RANKL interactions and treat osteoporosis.

鑒定可溶性RANKL上的一個結(jié)合位點,可作為抑制可溶性RANK-RANKL相互作用和治療骨質(zhì)疏松癥的目標。

242.Kinetic compartmentalization by unnatural reaction for itaconate production.

通過非自然反應生產(chǎn)衣康酸的動力學區(qū)劃。

243.Elucidation of divergent desaturation pathways in the formation of vinyl isonitrile and isocyanoacrylate.

闡明乙烯基異腈和異氰基丙烯酸酯形成過程中不同的脫飽和途徑。

244.Reactivating hippocampal-mediated memories during reconsolidation to disrupt fear.

在重新鞏固過程中重新激活海馬介導的記憶以破壞恐懼。

245.Life at high temperature observed in vitro upon laser heating of gold nanoparticles.

激光加熱金納米粒子后在體外觀察到的高溫生命。

246.Clonal hematopoiesis of indeterminate potential, DNA methylation, and risk for coronary artery disease.

不確定潛力的克隆造血,DNA甲基化和冠狀動脈疾病的風險。

247.An analysis modality for vascular structures combining tissue-clearing technology and topological data analysis.

一種結(jié)合組織清除技術和拓撲數(shù)據(jù)分析的血管結(jié)構分析模式。

248.A high-performance genetically encoded fluorescent indicator for in vivo cAMP imaging.

一種用于體內(nèi)cAMP成像的高性能基因編碼熒光指示劑。

249.Polyvinyl chloride degradation by a bacterium isolated from the gut of insect larvae.

從昆蟲幼蟲腸道中分離出的一種細菌對聚氯乙烯的降解。

363.Global patterns of vascular plant alpha diversity.

維管束植物阿爾法多樣性的全球模式。

364.Context-dependent function of TSLP and IL-1β in skin allergic sensitization and atopic march.

TSLP和IL-1β在皮膚過敏性致敏和特應性行進中的情境依賴功能。

365.Bacteria loaded with glucose polymer and photosensitive ICG silicon-nanoparticles for glioblastoma photothermal immunotherapy.

細菌裝載葡萄糖聚合物和光敏ICG硅納米粒子用于膠質(zhì)母細胞瘤光熱免疫治療。

a A scheme illustrating the construction of Trojan bacteria system. The nanoagents composed of silicon nanoparticle (SiNP) modified with glucose polymer (GP) (e.g, poly[4-O-(α-D-glucopyranosyl)-D-glucopyranose]) and indocyanine green (ICG) were internalized into bacterial cells (e.g., attenuated Salmonella typhimurium VNP20009 (VNP), Escherichia coli 25922 (EC)) through the bacteria-specific ATP-binding cassette (ABC) transporter to form the Trojan bacteria system (Trojan EC/VNP). b A scheme illustrating Trojan bacteria system crossing the blood–brain barrier (BBB), targeting and penetrating glioblastoma (GBM) tissues, followed by light-triggered photothermal immunotherapy of GBM in vivo.

a 說明木馬細菌系統(tǒng)構建的方案。 由葡萄糖聚合物 (GP)(例如,聚 [4-O-(α-D-吡喃葡萄糖基)-D-吡喃葡萄糖])和吲哚菁綠 (ICG) 修飾的硅納米顆粒 (SiNP) 組成的納米制劑被內(nèi)化到細菌細胞中 ( 例如,減毒的鼠傷寒沙門氏菌 VNP20009 (VNP)、大腸桿菌 25922 (EC))通過細菌特異性 ATP 結(jié)合盒 (ABC) 轉(zhuǎn)運體形成特洛伊木馬細菌系統(tǒng) (Trojan EC/VNP)。 b 該方案說明特洛伊木馬細菌系統(tǒng)穿過血腦屏障 (BBB),靶向并穿透膠質(zhì)母細胞瘤 (GBM) 組織,然后在體內(nèi)對 GBM 進行光觸發(fā)光熱免疫治療。

366.Decoding the olfactory map through targeted transcriptomics links murine olfactory receptors to glomeruli.

通過靶向轉(zhuǎn)錄組學解碼嗅覺地圖,將小鼠嗅覺受體與腎小球聯(lián)系起來。

367.Crosstalk between SUMOylation and ubiquitylation controls DNA end resection by maintaining MRE11 homeostasis on chromatin.

SUMOylation和泛素化之間的串聯(lián)通過維持染色質(zhì)上的MRE11平衡來控制DNA末端切除。

368.Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways.

心電圖QT間期及其組成部分的遺傳分析確定了額外的位點和途徑。

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【標題速讀】【Ncomm】【biological-sciences】【2022年】【9月】的評論 (共 條)

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