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【標(biāo)題速讀】【Sciadv】【2022年】【7月】

2023-05-30 23:36 作者:Rt_Cola  | 我要投稿

聲明:本專欄主要對(duì)生命科學(xué)領(lǐng)域的一些期刊文章標(biāo)題進(jìn)行翻譯,所有內(nèi)容均由本人手工整理翻譯。由于本人專業(yè)為生物分析相關(guān),其他領(lǐng)域如果出現(xiàn)翻譯錯(cuò)誤請(qǐng)諒解。

A 3D-printed human model slams hand-first against the water surface. The pointy front shape of this posture causes a slower increase of the slamming force compared to feet-first or head-first dives. Diving is a trait across the animal kingdom and its most common functions are to find prey and evade predators. Pandey et al. demonstrate how similarity of diving fronts (i.e., curved snouts, flat feet, or diving hand-first) unifies the slamming force across diving animals and humans. The authors elucidate the maximum height above which amateur diving leads to injury of the cervical spine, spinal cord, neck, collarbone, and knee, shedding light on a hydrodynamics-based protocol for safe high diving.

一個(gè) 3D 打印的人體模型先用手猛擊水面。 與腳先下水或頭先下水相比,這種姿勢(shì)的前尖形狀導(dǎo)致砰擊力的增加更慢。 潛水是整個(gè)動(dòng)物界的一個(gè)特征,其最常見的功能是尋找獵物和躲避捕食者。 潘迪等。 展示潛水前鋒(即彎曲的鼻子、扁平足或先潛水手)的相似性如何統(tǒng)一潛水動(dòng)物和人類的砰擊力。 作者闡明了業(yè)余潛水會(huì)導(dǎo)致頸椎、脊髓、頸部、鎖骨和膝蓋受傷的最大高度,闡明了基于流體動(dòng)力學(xué)的安全高空潛水方案。
A viral protein binding to a cell membrane. Across many viruses, the viral matrix protein coordinates the budding and release of new virions (complete, infective forms of a virus outside the host cell) from infected cells. Using x-ray crystallography, electron microscopy, and molecular dynamics, Norris et al. identify that lipid PI(4,5)P2 (orange, glowing) is critical for these viral proteins to interact with the host cell plasma membrane. This research could help in the development of potential therapeutic strategies to control paramyxovirus infections such as measles and Nipah.

一種與細(xì)胞膜結(jié)合的病毒蛋白。 在許多病毒中,病毒基質(zhì)蛋白協(xié)調(diào)新病毒粒子(宿主細(xì)胞外完整的感染形式的病毒)從受感染細(xì)胞中出芽和釋放。 使用 X 射線晶體學(xué)、電子顯微鏡和分子動(dòng)力學(xué),Norris 等人確定脂質(zhì) PI(4,5)P2(橙色,發(fā)光)對(duì)于這些病毒蛋白與宿主細(xì)胞質(zhì)膜相互作用至關(guān)重要。 這項(xiàng)研究可能有助于開發(fā)潛在的治療策略來控制副粘病毒感染,例如麻疹和尼帕病毒。
A natural octopus arm beside a synthetic, octopus-inspired arm with sensorized adhesives. Octopi possess controllable adhesives with intricately embedded sensing and processing, allowing them to manipulate a diverse array of underwater objects. Inspired by the octopus, Frey et al. developed rapidly switchable adhesives with tight integration of sensors, processing, and control for underwater manipulation. Integrated into a glove, the octopus-inspired adhesive skin detects objects and autonomously triggers the adhesives to pick up and release objects underwater, mimicking the advanced manipulation, sensing, and control of cephalopods to create a synthetic platform to reliably manipulate diverse underwater objects.

一條天然章魚手臂,旁邊是一條帶有感應(yīng)粘合劑的合成章魚手臂。 Octopi 擁有可控的粘合劑,具有復(fù)雜的嵌入式傳感和處理功能,使它們能夠操縱各種各樣的水下物體。 受到章魚的啟發(fā),F(xiàn)rey 等人開發(fā)了可快速切換的粘合劑,將傳感器、處理和水下操作控制緊密集成。 受章魚啟發(fā)的粘性皮膚集成到手套中,可檢測(cè)物體并自動(dòng)觸發(fā)粘合劑在水下拾取和釋放物體,模仿頭足類動(dòng)物的高級(jí)操縱、傳感和控制,以創(chuàng)建一個(gè)合成平臺(tái),以可靠地操縱各種水下物體。
Pharmaceutical researchers visualize and quantify protein level change in transplanted human organoids, tiny tissue cultures from stem cells. Determining whether new drugs will have the desired effect in humans has been a challenge during preclinical research. Westerling-Bui et al. approached this challenge by introducing human kidney organoids in rats to test a new drug, GFB-887. Their strategy could pave the way to establish a drug’s efficacy in humans during preclinical studies.

藥物研究人員可視化和量化移植的人體類器官(干細(xì)胞的微小組織培養(yǎng)物)中的蛋白質(zhì)水平變化。 在臨床前研究期間,確定新藥是否會(huì)對(duì)人類產(chǎn)生預(yù)期效果一直是一個(gè)挑戰(zhàn)。 Westerling-Bui 等人通過在大鼠中引入人腎類器官來測(cè)試新藥 GFB-887 來應(yīng)對(duì)這一挑戰(zhàn)。 他們的策略可以為在臨床前研究期間確定藥物對(duì)人體的療效鋪平道路。
In caves along the coasts of Mallorca, phreatic overgrowths on speleothems provide an accurate and mostly stable picture of past sea-level history. Onac et al. argue that a rapid sea-level rise event occurring about 3,000 years ago was caused by meltwater flux from the Antarctic Ice Sheet. The sheet's melting contributes to sea-level rise today. Between 2002-2019, the predicted rise was almost triple the highest average rate recorded in a 4,000-year history, supporting the authors' conclusion that modern global sea-level rise is an anomaly.

在馬略卡島沿岸的洞穴中,洞穴中的水下過度生長提供了過去海平面歷史的準(zhǔn)確且基本穩(wěn)定的圖像。 奧納克等認(rèn)為大約 3000 年前發(fā)生的海平面快速上升事件是由南極冰原的融水通量引起的。 薄板的融化導(dǎo)致了今天的海平面上升。 2002 年至 2019 年間,預(yù)測(cè)的上升速度幾乎是 4000 年歷史上最高平均速度的三倍,支持作者的結(jié)論,即現(xiàn)代全球海平面上升是一種異?,F(xiàn)象。


1.Presynaptic supervision of cortical spine dynamics in motor learning.

突觸前對(duì)運(yùn)動(dòng)學(xué)習(xí)中皮層脊柱動(dòng)態(tài)的監(jiān)督。

2.High-resolution imaging and manipulation of endogenous AMPA receptor surface mobility during synaptic plasticity and learning.

突觸可塑性和學(xué)習(xí)過程中內(nèi)源性AMPA受體表面流動(dòng)性的高分辨率成像和操作。

3.A quantitative biology approach correlates neuronal toxicity with the largest inclusions of TDP-43.

一種定量生物學(xué)方法將神經(jīng)元毒性與TDP-43的最大內(nèi)含物聯(lián)系起來。

4.Itch-specific neurons in the ventrolateral orbital cortex selectively modulate the itch processing.

外側(cè)眶皮層的癢特異性神經(jīng)元選擇性地調(diào)控癢的處理。

5.Switch of serotonergic descending inhibition into facilitation by a spinal chloride imbalance in neuropathic pain.

神經(jīng)性疼痛中脊髓氯化物不平衡使5-羥色胺能下降抑制作用轉(zhuǎn)為促進(jìn)作用。

6.Tracking and classifying Amazon fire events in near real time.

對(duì)亞馬遜火災(zāi)事件進(jìn)行近乎實(shí)時(shí)的跟蹤和分類。

7.Landscape-scale giant panda conservation based on metapopulations within China’s national park system.

基于中國國家公園系統(tǒng)內(nèi)元種群的大熊貓景觀保護(hù)。

8.Arctic Ocean Amplification in a warming climate in CMIP6 models.

CMIP6模型在氣候變暖中的北冰洋放大作用。

9.Enhanced simulated early 21st century Arctic sea ice loss due to CMIP6 biomass burning emissions.

由于CMIP6生物質(zhì)燃燒排放而導(dǎo)致的21世紀(jì)早期北極海冰損失的強(qiáng)化模擬。

10.CMOS electrochemical pH localizer-imager.

CMOS電化學(xué)pH定位儀-成像儀。

11.Rapid discovery of stable materials by coordinate-free coarse graining.

通過無坐標(biāo)粗?;焖侔l(fā)現(xiàn)穩(wěn)定材料。

12.Mechanism for selective binding of aromatic compounds on oxygen-rich graphene nanosheets based on molecule size/polarity matching.

基于分子大小/極性匹配的富氧石墨烯納米片上芳香族化合物的選擇性結(jié)合機(jī)制。

13.Self-adaptive virtual microchannel for continuous enrichment and separation of nanoparticles.

用于連續(xù)富集和分離納米粒子的自適應(yīng)虛擬微通道。

14.Unidirectionally excited phonon polaritons in high-symmetry orthorhombic crystals.

高對(duì)稱正方體晶體中的單向激發(fā)聲子偏振子.

15.Large magnetoelectric resistance in the topological Dirac semimetal α-Sn.

拓?fù)涞依税虢饘佴?Sn中的大磁電阻力。

16.Ultrasensitive point-of-care biochemical sensor based on metal-AIEgen frameworks.

基于金屬-AIEgen框架的超靈敏醫(yī)療點(diǎn)生化傳感器.

17.Through-skull brain imaging in vivo at visible wavelengths via dimensionality reduction adaptive-optical microscopy.

通過降維自適應(yīng)光學(xué)顯微鏡在體內(nèi)進(jìn)行可見光波長的穿顱腦成像。

18.Mapping pure plastic strains against locally applied stress: Revealing toughening plasticity.

繪制純塑性應(yīng)變與局部應(yīng)用應(yīng)力的關(guān)系圖:揭示了增韌的可塑性。

19.Slamming dynamics of diving and its implications for diving-related injuries.

潛水時(shí)的撞擊動(dòng)力學(xué)及其對(duì)潛水相關(guān)傷害的影響。

20.Meta-optic accelerators for object classifiers.

對(duì)象分類器的元光學(xué)加速器。

21.A biomineral-inspired approach of synthesizing colloidal persistent phosphors as a multicolor, intravital light source.

一種受生物礦物啟發(fā)的合成膠體持久性熒光粉的方法,作為一種多色的眼內(nèi)光源。

22.Alkali metal halide–coated perovskite redox catalysts for anaerobic oxidative dehydrogenation of n-butane.

用于正丁烷無氧氧化脫氫的堿金屬鹵化物包覆過氧化物催化劑。

23.Rapidly expanding spin-polarized exciton halo in a two-dimensional halide perovskite at room temperature.

室溫下二維鹵化物過氧化物中快速膨脹的自旋極化激子暈。

24.Highly efficient and nearly roll-off–free electrofluorescent devices via multiple sensitizations.

通過多重敏化實(shí)現(xiàn)高效和幾乎無滾降的電熒光裝置。

25.Design of a lithiophilic and electron-blocking interlayer for dendrite-free lithium-metal solid-state batteries.

用于無樹枝的鋰金屬固態(tài)電池的親鋰性和電子阻斷夾層的設(shè)計(jì)。

26.Momentum-matching and band-alignment van der Waals heterostructures for high-efficiency infrared photodetection.

用于高效紅外光檢測(cè)的動(dòng)量匹配和帶對(duì)準(zhǔn)范德瓦爾斯異質(zhì)結(jié)構(gòu)。

27.Versatile synthesis of dendritic mesoporous rare earth–based nanoparticles.

樹枝狀介孔稀土基納米粒子的多功能合成。

28.Artificially steering electrocatalytic oxygen evolution reaction mechanism by regulating oxygen defect contents in perovskites.

通過調(diào)節(jié)過氧化物中的氧缺陷含量,人為地引導(dǎo)電催化氧進(jìn)化反應(yīng)機(jī)制。

29.Spatially entangled photon pairs from lithium niobate nonlocal metasurfaces.

來自鈮酸鋰非局域元表面的空間糾纏光子對(duì).

30.Performing calculus with epsilon-near-zero metamaterials.

用epsilon-near-zero超材料進(jìn)行微積分。

31.Evidence for a neuromuscular circuit involving hypothalamic interleukin-6 in the control of skeletal muscle metabolism.

下丘腦白細(xì)胞介素-6參與控制骨骼肌代謝的神經(jīng)肌肉回路的證據(jù)。

32.Amphiphilic and fatigue-resistant organohydrogels for small-diameter vascular grafts.

用于小直徑血管移植物的兩親性和抗疲勞有機(jī)水凝膠。

33.Longer metaphase and fewer chromosome segregation errors in modern human than Neanderthal brain development.

現(xiàn)代人比尼安德特人腦部發(fā)育的分裂期更長,染色體分離錯(cuò)誤更少。

34.Mitochondrial proteostasis stress in muscle drives a long-range protective response to alleviate dietary obesity independently of ATF4.

肌肉中的線粒體蛋白酶壓力驅(qū)動(dòng)長程保護(hù)性反應(yīng),以緩解獨(dú)立于ATF4的飲食性肥胖癥。

35.Chaperoning of the histone octamer by the acidic domain of DNA repair factor APLF.

DNA修復(fù)因子APLF的酸性結(jié)構(gòu)域?qū)M蛋白八聚體的伴侶作用。

36.ATP-competitive inhibitors modulate the substrate binding cooperativity of a kinase by altering its conformational entropy.

ATP競爭性抑制劑通過改變激酶的構(gòu)象熵來調(diào)節(jié)激酶的底物結(jié)合合作性。

37.Ancient herpes simplex 1 genomes reveal recent viral structure in Eurasia.

古老的單純皰疹1基因組揭示了歐亞大陸近期的病毒結(jié)構(gòu)。

38.Nonrandom sister chromatid segregation mediates rDNA copy number maintenance in Drosophila.

非隨機(jī)姐妹染色體分離介導(dǎo)果蠅的rDNA拷貝數(shù)維持。

39.SMAD4, activated by the TCR-triggered MEK/ERK signaling pathway, critically regulates CD8+ T cell cytotoxic function.

由TCR觸發(fā)的MEK/ERK信號(hào)通路激活的SMAD4關(guān)鍵性地調(diào)節(jié)CD8+T細(xì)胞的細(xì)胞毒性功能。

40.Dissecting motor skill acquisition: Spatial coordinates take precedence.

剖析運(yùn)動(dòng)技能的獲得:?空間坐標(biāo)優(yōu)先。

41.Targeted BACE-1 inhibition in microglia enhances amyloid clearance and improved cognitive performance.

小膠質(zhì)細(xì)胞中靶向BACE-1的抑制增強(qiáng)了淀粉樣蛋白的清除和認(rèn)知能力的提高。

42.Cocaine preference and neuroadaptations are maintained by astrocytic NMDA receptors in the nucleus accumbens.

可卡因偏好和神經(jīng)適應(yīng)由阿肯色核中的星形細(xì)胞NMDA受體維持。

43.Plant diversity reduces satellite-observed phenological variability in wetlands at a national scale.

植物多樣性在全國范圍內(nèi)減少了衛(wèi)星觀測(cè)到的濕地物候變化。

44.How does salinity shape ocean circulation and ice geometry on Enceladus and other icy satellites?.

鹽度如何塑造恩克拉多斯和其他冰衛(wèi)星上的海洋循環(huán)和冰的幾何形狀?

45.Future seasonal changes in habitat for Arctic whales during predicted ocean warming.

預(yù)測(cè)海洋變暖期間北極鯨魚棲息地的未來季節(jié)性變化。

46.Global reduction in ship-tracks from sulfur regulations for shipping fuel.

航運(yùn)燃料的硫磺法規(guī)導(dǎo)致的全球船舶軌道的減少。

47.Microrobotic swarms for selective embolization.

用于選擇性栓塞的微型機(jī)器人群。

48.Momentum space imaging of σ orbitals for chemical analysis.

用于化學(xué)分析的σ軌道的動(dòng)量空間成像。

49.Imaging mesoscopic antiferromagnetic spin textures in the dilute limit from single-geometry resonant coherent x-ray diffraction.

通過單幾何共振相干X射線衍射,在稀釋極限下對(duì)介觀反鐵磁自旋紋理成像。

50.Machine learning enables interpretable discovery of innovative polymers for gas separation membranes.

機(jī)器學(xué)習(xí)使氣體分離膜的創(chuàng)新聚合物的可解釋性發(fā)現(xiàn)。

51.Differences in ion-RNA binding modes due to charge density variations explain the stability of RNA in monovalent salts.

電荷密度變化導(dǎo)致的離子-RNA結(jié)合模式的差異解釋了RNA在單價(jià)鹽中的穩(wěn)定性。

52.Negative reflection of nanoscale-confined polaritons in a low-loss natural medium.

低損耗自然介質(zhì)中納米級(jí)封閉極子的負(fù)向反射。

53.Circularity in mixed-plastic chemical recycling enabled by variable rates of polydiketoenamine hydrolysis.

聚二酮烯胺水解率的變化使混合塑料化學(xué)回收中的循環(huán)性得以實(shí)現(xiàn)。

54.Snapshots of a light-induced metastable hidden phase driven by the collapse of charge order.

由電荷秩序崩潰驅(qū)動(dòng)的光誘導(dǎo)的可轉(zhuǎn)移隱藏相的快照。

55.Relayed hyperpolarization for zero-field nuclear magnetic resonance.

零場核磁共振的中繼超極化。

56.Noncanonical activation of GLI signaling in SOX2+ cells drives medulloblastoma relapse.

SOX2+細(xì)胞中GLI信號(hào)的非規(guī)范性激活驅(qū)動(dòng)髓母細(xì)胞瘤復(fù)發(fā)。

57.Cationic nanoparticles enhance T cell tumor infiltration and antitumor immune responses to a melanoma vaccine.

陽離子納米顆粒增強(qiáng)T細(xì)胞腫瘤浸潤和對(duì)黑色素瘤疫苗的抗腫瘤免疫反應(yīng)。

58.Structural basis for tunable control of actin dynamics by myosin-15 in mechanosensory stereocilia.

肌球蛋白-15在機(jī)械感覺立體細(xì)胞中可調(diào)控肌動(dòng)蛋白動(dòng)態(tài)的結(jié)構(gòu)基礎(chǔ)。

59.Spatiotemporal gating of Stat nuclear influx by Drosophila Npas4 in collective cell migration.

果蠅Npas4在細(xì)胞集體遷移中對(duì)Stat核流入的時(shí)空門控。

60.An implantable ultrasound-powered device for the treatment of brain cancer using electromagnetic fields.

一種利用電磁場治療腦癌的植入式超聲供電裝置。

61.Multiepitope supramolecular peptide nanofibers eliciting coordinated humoral and cellular antitumor immune responses.

引起協(xié)調(diào)的體液和細(xì)胞抗腫瘤免疫反應(yīng)的多表位超分子肽納米纖維。

62.Therapeutic KRASG12C inhibition drives effective interferon-mediated antitumor immunity in immunogenic lung cancers.

治療性KRASG12C抑制推動(dòng)了免疫性肺癌的有效干擾素介導(dǎo)的抗腫瘤免疫。

63.Engineered immunomodulatory accessory cells improve experimental allogeneic islet transplantation without immunosuppression.

工程化的免疫調(diào)節(jié)附屬細(xì)胞改善了實(shí)驗(yàn)性同種異體胰腺移植而不需要免疫抑制。

64.Measles and Nipah virus assembly: Specific lipid binding drives matrix polymerization.

麻疹和尼帕病毒的組裝:?特異性脂質(zhì)結(jié)合驅(qū)動(dòng)基質(zhì)聚合。

65.14-3-3-zeta mediates GLP-1 receptor agonist action to alter α cell proglucagon processing.

14-3-zeta介導(dǎo)GLP-1受體激動(dòng)劑作用,改變?chǔ)良?xì)胞胰高血糖素處理。

66.Epigenetic controls of Sonic hedgehog guarantee fidelity of epithelial adult stem cells trajectory in regeneration.

Sonic hedgeh的表觀遺傳控制保證了上皮成人干細(xì)胞再生軌跡的保真度。

67.Multiplexed high-throughput localized electroporation workflow with deep learning–based analysis for cell engineering.

基于深度學(xué)習(xí)的細(xì)胞工程分析的多重高通量局部電穿孔工作流程。

68.The ER protein Creld regulates ER-mitochondria contact dynamics and respiratory complex 1 activity.

ER蛋白Creld調(diào)控ER-mitochondria接觸動(dòng)力學(xué)和呼吸復(fù)合體1的活性。

69.Tunneling nanotubes provide a route for SARS-CoV-2 spreading.

隧道式納米管為SARS-CoV-2的傳播提供了一條途徑。

70.G6PD-mediated increase in de novo NADP+ biosynthesis promotes antioxidant defense and tumor metastasis.

G6PD介導(dǎo)的新NADP+生物合成的增加促進(jìn)抗氧化防御和腫瘤轉(zhuǎn)移。

71.Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment.

人類瑞諾丁受體2型通道的結(jié)構(gòu)分析揭示了心臟猝死的機(jī)制和治療方法。

72.Hypoxia-mediated stabilization of HIF1A in prostatic intraepithelial neoplasia promotes cell plasticity and malignant progression.

前列腺上皮內(nèi)瘤的低氧介導(dǎo)的HIF1A穩(wěn)定化促進(jìn)細(xì)胞可塑性和惡性進(jìn)展。

73.Cloning and base editing of GFP transgenic rhesus monkey and off-target analysis.

GFP轉(zhuǎn)基因恒河猴的克隆和堿基編輯及脫靶分析。

74.Electro-mechanical coupling of KCNQ channels is a target of epilepsy-associated mutations and retigabine.

KCNQ通道的電-機(jī)械耦合是癲癇相關(guān)突變和瑞替加濱的目標(biāo)。

75.Microtubule-binding core of the tau protein.

tau蛋白的微管結(jié)合核心。

76.Uncovering temporospatial sensitive TBI targeting strategies via in vivo phage display.

通過體內(nèi)噬菌體展示揭示時(shí)空敏感的TBI靶向策略。

77.Polymeric nanoparticles for dual-targeted theranostic gene delivery to hepatocellular carcinoma.

聚合物納米顆粒用于肝細(xì)胞癌的雙靶向治療基因遞送.

78.Genomic epidemiological models describe pathogen evolution across fitness valleys.

基因組流行病學(xué)模型描述了病原體跨越健身谷地的進(jìn)化。

79.Resolving the molecular architecture of the photoreceptor active zone with 3D-MINFLUX.

用3D-MINFLUX解析光感受器活動(dòng)區(qū)的分子結(jié)構(gòu)。

80.Mapping microstructural gradients of the human striatum in normal aging and Parkinson’s disease.

繪制人類紋狀體在正常衰老和帕金森病中的微結(jié)構(gòu)梯度圖。

81.Reassessing hierarchical correspondences between brain and deep networks through direct interface.

通過直接接口重新評(píng)估大腦和深度網(wǎng)絡(luò)之間的層次對(duì)應(yīng)關(guān)系。

82.Neuronal activity induces glucosylceramide that is secreted via exosomes for lysosomal degradation in glia.

神經(jīng)元活動(dòng)誘導(dǎo)葡糖甘油酰胺通過外泌體分泌,在膠質(zhì)細(xì)胞中進(jìn)行溶酶體降解。

83.Mechanical gating of the auditory transduction channel TMC1 involves the fourth and sixth transmembrane helices.

聽覺轉(zhuǎn)導(dǎo)通道TMC1的機(jī)械門控涉及第四和第六跨膜螺旋。

84.Near-field probing of image phonon-polaritons in hexagonal boron nitride on gold crystals.

金晶體上六方氮化硼中圖像聲子-極化子的近場探測(cè)。

85.Programmed shape-morphing into complex target shapes using architected dielectric elastomer actuators.

利用結(jié)構(gòu)化的電介質(zhì)彈性致動(dòng)器實(shí)現(xiàn)復(fù)雜目標(biāo)形狀的程序化變形。

86.Ultrastable tip-enhanced hyperspectral optical nanoimaging for defect analysis of large-sized WS2 layers.

用于大尺寸WS2層缺陷分析的超穩(wěn)定尖端增強(qiáng)高光譜光學(xué)納米成像技術(shù)。

87.Magnetically steerable bacterial microrobots moving in 3D biological matrices for stimuli-responsive cargo delivery.

在三維生物基質(zhì)中移動(dòng)的可磁轉(zhuǎn)向的細(xì)菌微機(jī)器人,用于刺激響應(yīng)的貨物輸送。

88.Fast constructing polarity-switchable zinc-bromine microbatteries with high areal energy density.

快速構(gòu)建具有高面積能量密度的極性轉(zhuǎn)換鋅溴微電池。

89.Sequential vacuum-evaporated perovskite solar cells with more than 24% efficiency.

效率超過24%的序貫真空蒸發(fā)過氧化物太陽能電池。

90.RASER MRI: Magnetic resonance images formed spontaneously exploiting cooperative nonlinear interaction.

RASER MRI:?利用合作性非線性互動(dòng)自發(fā)形成的磁共振圖像。

91.Designing broadband pulsed dynamic nuclear polarization sequences in static solids.

設(shè)計(jì)靜態(tài)固體中的寬帶脈沖動(dòng)態(tài)核偏振序列。

92.Octopus-inspired adhesive skins for intelligent and rapidly switchable underwater adhesion.

用于智能和快速切換的水下粘性的章魚啟發(fā)的粘性皮膚。

93.Femtosecond photoelectron circular dichroism of chemical reactions.

化學(xué)反應(yīng)的飛秒光電子圓二色性。

94.A limit on the evolutionary rescue of an Antarctic bacterium from rising temperatures.

南極細(xì)菌從溫度上升中獲得進(jìn)化救援的極限。

95.Mechanical regulation of talin through binding and history-dependent unfolding.

通過結(jié)合和歷史依賴性展開對(duì)滑石蛋白的機(jī)械調(diào)節(jié)。

96.Leveraging gene therapy to achieve long-term continuous or controllable expression of biotherapeutics.

利用基因療法實(shí)現(xiàn)生物治療劑的長期連續(xù)或可控表達(dá)。

97.Tracking the immune response by MRI using biodegradable and ultrasensitive microprobes.

使用生物可降解和超靈敏的微探針通過MRI追蹤免疫反應(yīng)。

98.Investigating trends in those who experience menstrual bleeding changes after SARS-CoV-2 vaccination.

調(diào)查SARS-CoV-2疫苗接種后出現(xiàn)月經(jīng)出血變化者的趨勢(shì)。

99.An integrated model for termination of RNA polymerase III transcription.

RNA聚合酶III轉(zhuǎn)錄終止的綜合模型.

100.Targeting oxidized phospholipids by AAV-based gene therapy in mice with established hepatic steatosis prevents progression to fibrosis.

以AAV為基礎(chǔ)的基因療法在已形成的肝脂肪變性的小鼠中靶向氧化磷脂,可以防止進(jìn)展為纖維化。

101.RRM2 enhances MYCN-driven neuroblastoma formation and acts as a synergistic target with CHK1 inhibition.

RRM2增強(qiáng)了MYCN驅(qū)動(dòng)的神經(jīng)母細(xì)胞瘤的形成,并作為與CHK1抑制作用的協(xié)同目標(biāo)。

102.Microbial genomic trait evolution is dominated by frequent and rare pulsed evolution.

微生物基因組性狀進(jìn)化以頻繁和罕見的脈沖式進(jìn)化為主。

103.Recombinant DTβ4-inspired porous 3D vascular graft enhanced antithrombogenicity and recruited circulating CD93+/CD34+ cells for endothelialization.

重組DTβ4啟發(fā)的多孔三維血管移植增強(qiáng)了抗血栓性并招募循環(huán)CD93+/CD34+細(xì)胞進(jìn)行內(nèi)皮化。

104.Cell disorientation by loss of SHH-dependent mechanosensation causes cyclopia.

SHH依賴性機(jī)械感覺的喪失導(dǎo)致細(xì)胞迷失方向,從而引起旋光癥。

105.Engineered ACE2-Fc counters murine lethal SARS-CoV-2 infection through direct neutralization and Fc-effector activities.

工程化的ACE2-Fc通過直接中和和Fc效應(yīng)活性對(duì)抗小鼠致命的SARS-CoV-2感染。

106.The two-domain elevator-type mechanism of zinc-transporting ZIP proteins.

鋅轉(zhuǎn)運(yùn)ZIP蛋白的雙域電梯型機(jī)制。

107.ZMYND8 is a master regulator of 27-hydroxycholesterol that promotes tumorigenicity of breast cancer stem cells.

ZMYND8是促進(jìn)乳腺癌干細(xì)胞致瘤性的27-羥基膽固醇的主調(diào)控因子。

108.Experimental and computational understanding of pulsatile release mechanism from biodegradable core-shell microparticles.

生物可降解核殼微粒子的脈沖式釋放機(jī)制的實(shí)驗(yàn)和計(jì)算理解。

109.Global protein dynamics as communication sensors in peptide synthetase domains.

肽合成酶域中作為通信傳感器的全局蛋白動(dòng)力學(xué)。

110.Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias.

非典型趨化因子受體3的結(jié)構(gòu)揭示了其雜交性和信號(hào)偏向的基礎(chǔ)。

111.Leptin receptor signaling sustains metabolic fitness of alveolar macrophages to attenuate pulmonary inflammation.

瘦肉精受體信號(hào)維持肺泡巨噬細(xì)胞的代謝能力以減輕肺部炎癥。

112.Pluripotency factors regulate the onset of Hox cluster activation in the early embryo.

多能性因子調(diào)節(jié)早期胚胎中Hox簇的啟動(dòng)。

113.Cis-regulatory chromatin loops analysis identifies GRHL3 as a master regulator of surface epithelium commitment.

順式調(diào)控染色質(zhì)環(huán)分析確定了GRHL3是表面上皮細(xì)胞承諾的主調(diào)控者。

114.Overexpression of the scopoletin biosynthetic pathway enhances lignocellulosic biomass processing.

莨菪堿生物合成途徑的過量表達(dá)增強(qiáng)了木質(zhì)纖維素生物質(zhì)的加工。

115.CRISPR interference interrogation of COPD GWAS genes reveals the functional significance of desmoplakin in iPSC-derived alveolar epithelial cells.

對(duì)COPD GWAS基因的CRISPR干擾訊問揭示了iPSC衍生的肺泡上皮細(xì)胞中desmoplakin的功能意義。

116.Nanocapping-enabled charge reversal generates cell-enterable endosomal-escapable bacteriophages for intracellular pathogen inhibition.

Nanocapping-enabled?電荷反轉(zhuǎn)生成細(xì)胞進(jìn)入內(nèi)體逃逸噬菌體用于細(xì)胞內(nèi)病原體抑制。

117.Alzheimer’s disease: Ablating single master site abolishes tau hyperphosphorylation.

阿爾茨海默?。?消減單一主位點(diǎn)可廢除tau的高磷酸化。

118.Reward ameliorates depressive-like behaviors via inhibition of the substantia innominata to the lateral habenula projection.

獎(jiǎng)賞通過抑制無基質(zhì)到外側(cè)哈貝納的投射來改善抑郁癥樣行為。

119.Near-zero cohesion and loose packing of Bennu’s near subsurface revealed by spacecraft contact.

航天器接觸所揭示的貝努近地表的近零內(nèi)聚力和松散包裝。

120.Role of tropical lower stratosphere winds in quasi-biennial oscillation disruptions.

熱帶低平流層風(fēng)在準(zhǔn)兩年期振蕩破壞中的作用。

121.Deep ocean microbial communities produce more stable dissolved organic matter through the succession of rare prokaryotes.

深海微生物群落通過稀有原核生物的演替產(chǎn)生更穩(wěn)定的溶解有機(jī)物。

122.Direct and indirect impacts of urbanization on vegetation growth across the world’s cities.

城市化對(duì)世界各城市植被生長的直接和間接影響。

123.High-resolution spatial and genomic characterization of coral-associated microbial aggregates in the coral Stylophora pistillata.

珊瑚Stylophora pistillata中珊瑚相關(guān)微生物聚集的高分辨率空間和基因組特征。

124.Metamorphic diamond from the northeastern margin of Gondwana: Paradigm shifting implications for one of Earth’s largest orogens.

來自岡瓦納東北緣的變質(zhì)鉆石:?地球上最大的造山地之一的范式轉(zhuǎn)變的影響。

125.The “teapot in a city”: A paradigm shift in urban climate modeling.

城市中的茶壺":?城市氣候建模的范式轉(zhuǎn)變。

126.FIDELITY: A quality control system for droplet microfluidics.

FIDELITY:液滴微流控技術(shù)的質(zhì)量控制系統(tǒng)。

127.Strong mode coupling-enabled hybrid photon-plasmon laser with a microfiber-coupled nanorod.

用微纖維耦合的納米棒實(shí)現(xiàn)強(qiáng)模式耦合的混合光子-等離子體激光。

128.Storage and analysis of light-matter entanglement in a fiber-integrated system.

光纖集成系統(tǒng)中光-物質(zhì)糾纏的存儲(chǔ)和分析。

129.The seeds and homogeneous nucleation of photoinduced nonthermal melting in semiconductors due to self-amplified local dynamic instability.

由于自我放大的局部動(dòng)態(tài)不穩(wěn)定性,半導(dǎo)體中光誘導(dǎo)的非熱熔化的種子和均質(zhì)成核。

130.Controlling and visualizing Dirac physics in topological semimetal heterostructures.

拓?fù)浒虢饘佼愘|(zhì)結(jié)構(gòu)中狄拉克物理的控制和可視化。

131.Homeostatic neuro-metasurfaces for dynamic wireless channel management.

用于動(dòng)態(tài)無線信道管理的穩(wěn)態(tài)神經(jīng)元表面。

132.Rapid liquid phase–assisted ultrahigh-temperature sintering of high-entropy ceramic composites.

高熵陶瓷復(fù)合材料的快速液相輔助超高溫?zé)Y(jié)。

133.A handheld intelligent single-molecule binary bioelectronic system for fast and reliable immunometric point-of-care testing.

用于快速和可靠的免疫測(cè)量醫(yī)療點(diǎn)測(cè)試的手持式智能單分子二元生物電子系統(tǒng)。

134.Metal-carbide eutectics with multiprincipal elements make superrefractory alloys.

具有多主元素的金屬碳化物共晶使超難熔合金。

135.Battery-free, tuning circuit–inspired wireless sensor systems for detection of multiple biomarkers in bodily fluids.

無電池、調(diào)諧電路啟發(fā)的無線傳感器系統(tǒng),用于檢測(cè)體液中的多種生物標(biāo)志物。

136.Molecular doped, color-tunable, high-mobility, emissive, organic semiconductors for light-emitting transistors.

用于發(fā)光晶體管的分子摻雜、顏色可調(diào)、高流動(dòng)性、發(fā)光的有機(jī)半導(dǎo)體。

137.Light-induced charged slippery surfaces.

光誘導(dǎo)的帶電滑動(dòng)表面。

138.Instability mediated self-templating of drop crystals.

水滴晶體的不穩(wěn)定性介導(dǎo)的自我模板化。

139.Direct search for dark matter axions excluding ALP cogenesis in the 63- to 67-μeV range with the ORGAN experiment.

用ORGAN實(shí)驗(yàn)直接搜索63-67μeV范圍內(nèi)排除ALP成因的暗物質(zhì)軸子。

140.Computational design of a sensitive, selective phase-changing sensor protein for the VX nerve agent.

針對(duì)VX神經(jīng)毒劑的敏感、選擇性相變傳感器蛋白的計(jì)算設(shè)計(jì)。

141.Transplanted organoids empower human preclinical assessment of drug candidate for the clinic.

移植的器官賦予人類臨床前評(píng)估候選藥物的能力,以用于臨床。

142.HP1 oligomerization compensates for low-affinity H3K9me recognition and provides a tunable mechanism for heterochromatin-specific localization.

HP1低聚物補(bǔ)償了低親和力的H3K9me識(shí)別,為異染色質(zhì)特異性定位提供了一個(gè)可調(diào)整的機(jī)制。

143.Interrogating glioma-M2 macrophage interactions identifies Gal-9/Tim-3 as a viable target against PTEN-null glioblastoma.

審問膠質(zhì)瘤-M2巨噬細(xì)胞的相互作用,確定Gal-9/Tim-3是對(duì)抗PTEN缺失的膠質(zhì)母細(xì)胞瘤的可行目標(biāo)。

144.Preferred synonymous codons are translated more accurately: Proteomic evidence, among-species variation, and mechanistic basis.

優(yōu)選的同義密碼子被翻譯得更準(zhǔn)確:蛋白質(zhì)組學(xué)證據(jù)、物種間差異和機(jī)制基礎(chǔ)。

145.Rapid adaptive radiation of Darwin’s finches depends on ancestral genetic modules.

達(dá)爾文雀的快速適應(yīng)性輻射取決于祖先的遺傳模塊。

146.Tumoral microenvironment prevents de novo asparagine biosynthesis in B cell lymphoma, regardless of ASNS expression.

腫瘤微環(huán)境阻止B細(xì)胞淋巴瘤的天冬酰胺生物合成,與ASNS表達(dá)無關(guān)。

147.Systematic simulation of the interactions of pleckstrin homology domains with membranes.

系統(tǒng)模擬pleckstrin同源結(jié)構(gòu)域與膜的相互作用。

148.ECM-mimetic immunomodulatory hydrogel for methicillin-resistant Staphylococcus aureus–infected chronic skin wound healing.

用于耐甲氧西林金黃色葡萄球菌感染的慢性皮膚傷口愈合的仿ECM免疫調(diào)節(jié)水凝膠。

149.A lineage-specific Exo70 is required for receptor kinase–mediated immunity in barley.

大麥中受體激酶介導(dǎo)的免疫需要一種線型特異性的Exo70。

150.Trans-splicing facilitated by RNA pairing greatly expands sDscam isoform diversity but not homophilic binding specificity.

RNA配對(duì)促進(jìn)的跨剪接極大地?cái)U(kuò)展了sDscam異構(gòu)體的多樣性,但沒有擴(kuò)大同源結(jié)合特異性。

151.Cryo-EM structure of the HIV-1 Pol polyprotein provides insights into virion maturation.

HIV-1 Pol多聚蛋白的低溫EM結(jié)構(gòu)提供了對(duì)病毒成熟的見解。

152.Progerin modulates the IGF-1R/Akt signaling involved in aging.

Progerin調(diào)控參與衰老的IGF-1R/Akt信號(hào)傳導(dǎo)。

153.Structural basis for the calmodulin-mediated activation of eukaryotic elongation factor 2 kinase.

鈣調(diào)蛋白介導(dǎo)的真核生物延長因子2激酶激活的結(jié)構(gòu)基礎(chǔ)。

154.A phospho-tyrosine–based signaling module using SPOP, CSK, and LYN controls TLR-induced IRF activity.

使用SPOP、CSK和LYN的基于磷酸酪氨酸的信號(hào)模塊控制TLR誘導(dǎo)的IRF活性。

155.Socioecological vulnerability and the risk of zoonotic disease emergence in Brazil.

巴西社會(huì)生態(tài)的脆弱性和人畜共患疾病出現(xiàn)的風(fēng)險(xiǎn)。

156.Deep learning–based integration of genetics with registry data for stratification of schizophrenia and depression.

基于深度學(xué)習(xí)的遺傳學(xué)與注冊(cè)表數(shù)據(jù)整合,用于精神分裂癥和抑郁癥的分層。

157.The impact of C-tactile low-threshold mechanoreceptors on affective touch and social interactions in mice.

C-觸覺低閾值機(jī)械感受器對(duì)小鼠情感觸覺和社會(huì)互動(dòng)的影響。

158.Competing and accelerating effects of anthropogenic nutrient inputs on climate-driven changes in ocean carbon and oxygen cycles.

人為營養(yǎng)輸入對(duì)氣候驅(qū)動(dòng)的海洋碳和氧循環(huán)變化的競爭和加速效應(yīng)。

159.Exceptionally stable preindustrial sea level inferred from the western Mediterranean Sea.

從西地中海推斷出的異常穩(wěn)定的工業(yè)化前海平面。

160.Group size affects predation risk and foraging success in Pacific salmon at sea.

群體大小影響太平洋鮭魚在海上的捕食風(fēng)險(xiǎn)和覓食成功率。

161.Risks of mining to salmonid-bearing watersheds.

采礦對(duì)含鮭魚的流域的風(fēng)險(xiǎn)。

162.Strong floristic distinctiveness across Neotropical successional forests.

新熱帶演替森林中強(qiáng)烈的植物學(xué)特征。

163.Anoxic photochemical weathering of pyrite on Archean continents.

Archean大陸上黃鐵礦的缺氧光化學(xué)風(fēng)化作用。

164.Enhanced phosphorus recycling during past oceanic anoxia amplified by low rates of apatite authigenesis.

過去海洋缺氧期間磷循環(huán)的增強(qiáng)被低速率的磷灰石生成所放大。

165.Reviving ghost alleles: Genetically admixed coyotes along the American Gulf Coast are critical for saving the endangered red wolf.

復(fù)活的幽靈等位基因:?美國墨西哥灣沿岸的基因混雜的小狼對(duì)拯救瀕危的紅狼至關(guān)重要。

166.Resilience of infaunal ecosystems during the Early Triassic greenhouse Earth.

早三疊紀(jì)溫室地球期間無脊椎動(dòng)物生態(tài)系統(tǒng)的復(fù)原力。

167.Migration and transformation of coastal wetlands in response to rising seas.

沿海濕地在應(yīng)對(duì)海平面上升時(shí)的遷移和轉(zhuǎn)變。

168.Arctic ice and the ecological rise of the dinosaurs.

北極冰與恐龍的生態(tài)崛起。

169.Dynamic network of intermolecular interactions in metal-organic frameworks functionalized by molecular machines.

分子機(jī)功能化的金屬有機(jī)框架中分子間相互作用的動(dòng)態(tài)網(wǎng)絡(luò)。

170.Superdurable and fire-retardant structural coloration of carbon nanotubes.

碳納米管的超耐久性和阻燃性結(jié)構(gòu)著色。

171.Resolving the different bulk moduli within individual soft nanogels using small-angle neutron scattering.

利用小角中子散射解決單個(gè)軟質(zhì)納米凝膠內(nèi)的不同體模數(shù)。

172.Arrested-motility states in populations of shape-anisotropic active Janus particles.

形狀各異的活性Janus顆粒群中的停滯運(yùn)動(dòng)狀態(tài)。

173.Microscale mechanochemical characterization of drying oil films by in situ correlative Brillouin and Raman spectroscopy.

通過原位相關(guān)布里淵和拉曼光譜對(duì)干燥油膜進(jìn)行微觀機(jī)械化學(xué)表征。

174.Mismatched ligand density enables ordered assembly of mixed-dimensional, cross-species materials.

不匹配的配體密度使混合維度、跨物種材料的有序組裝。

175.In vivo multidimensional CRISPR screens identify Lgals2 as an immunotherapy target in triple-negative breast cancer.

體內(nèi)多維CRISPR篩選確定Lgals2為三陰性乳腺癌的免疫治療目標(biāo)。

176.The key micronutrient copper orchestrates broad-spectrum virus resistance in rice.

關(guān)鍵微量營養(yǎng)素銅協(xié)調(diào)了水稻的廣譜抗病毒性。

177.Performance of islets of Langerhans conformally coated via an emulsion cross-linking method in diabetic rodents and nonhuman primates.

通過乳劑交聯(lián)法對(duì)糖尿病嚙齒動(dòng)物和非人靈長類動(dòng)物進(jìn)行保形涂布的朗格漢斯小鼠的性能。

178.Profiling of mature-stage human breast milk cells identifies six unique lactocyte subpopulations.

成熟期人類乳腺細(xì)胞的分析確定了六個(gè)獨(dú)特的乳腺細(xì)胞亞群。

179.Measuring competitive exclusion in non–small cell lung cancer.

測(cè)量非小細(xì)胞肺癌的競爭性排異。

180.Immunomodulatory actions of a kynurenine-derived endogenous electrophile.

犬尿喹啉衍生的內(nèi)源性親電子體的免疫調(diào)節(jié)作用。

181.Identification of an integrase-independent pathway of retrotransposition.

識(shí)別一個(gè)不依賴整合酶的逆轉(zhuǎn)錄途徑。

182.Dynamic instability of dendrite tips generates the highly branched morphologies of sensory neurons.

樹突尖端的動(dòng)態(tài)不穩(wěn)定性產(chǎn)生了感覺神經(jīng)元的高度分枝形態(tài)。

183.ParB proteins can bypass DNA-bound roadblocks via dimer-dimer recruitment.

ParB蛋白可以通過二聚體-二聚體招募繞過DNA結(jié)合的路障。

184.Suppression of osteoclast multinucleation via a posttranscriptional regulation–based spatiotemporally selective delivery system.

通過基于轉(zhuǎn)錄后調(diào)控的時(shí)空選擇性傳遞系統(tǒng)抑制破骨細(xì)胞的多核化。

185.Molecular mechanism of S-adenosylmethionine sensing by SAMTOR in mTORC1 signaling.

SAMTOR在mTORC1信號(hào)傳導(dǎo)中感應(yīng)S-腺苷蛋氨酸的分子機(jī)制。

186.Biological chemotaxis-guided self-thermophoretic nanoplatform augments colorectal cancer therapy through autonomous mucus penetration.

生物趨化性引導(dǎo)的自熱納米平臺(tái)通過自主粘液滲透增強(qiáng)結(jié)直腸癌治療。

187.CPK28-NLP7 module integrates cold-induced Ca2+ signal and transcriptional reprogramming in Arabidopsis.

CPK28-NLP7模塊整合了擬南芥中冷誘導(dǎo)的Ca2+信號(hào)和轉(zhuǎn)錄重編程。

188.Activation of the human chemokine receptor CX3CR1 regulated by cholesterol.

膽固醇調(diào)節(jié)的人類趨化因子受體CX3CR1的激活。

189.Immunotherapy of glioblastoma explants induces interferon-γ responses and spatial immune cell rearrangements in tumor center, but not periphery.

膠質(zhì)母細(xì)胞瘤外植體的免疫治療誘導(dǎo)了干擾素-γ反應(yīng)和腫瘤中心的空間免疫細(xì)胞重排,但不是外圍。

190.NAC1 modulates autoimmunity by suppressing regulatory T cell–mediated tolerance.

NAC1通過抑制調(diào)節(jié)性T細(xì)胞介導(dǎo)的耐受來調(diào)節(jié)自身免疫力。

191.Cas9/Nickase-induced allelic conversion by homologous chromosome-templated repair in Drosophila somatic cells.

Cas9/Nickase在果蠅體細(xì)胞中通過同源染色體修復(fù)誘導(dǎo)的等位基因轉(zhuǎn)換。

192.Efficient delivery of a DNA aptamer-based biosensor into plant cells for glucose sensing through thiol-mediated uptake.

通過硫醇介導(dǎo)的攝取將基于DNA誘導(dǎo)體的生物傳感器有效地傳遞到植物細(xì)胞中,以實(shí)現(xiàn)葡萄糖感應(yīng)。

193.The central clock suffices to drive the majority of circulatory metabolic rhythms.

中央時(shí)鐘足以驅(qū)動(dòng)大多數(shù)循環(huán)系統(tǒng)的代謝節(jié)律。

194.Polyzoa is back: The effect of complete gene sets on the placement of Ectoprocta and Entoprocta.

聚生菌回來了:?完整的基因組對(duì)Ectoprocta和Entoprocta的位置的影響。



【標(biāo)題速讀】【Sciadv】【2022年】【7月】的評(píng)論 (共 條)

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