目錄

Day 1: November 3

Welcoming Remarks

Ponpan Matangkasombut Choopong

Varodom Charoensawan

Opening Speech

Chair: Ponpan Matangkasombut Choopong

Speaker: Pattarachai Kiratisin

?

State of HCA and HCA Asia

Chair: Varodom Charoensawan

Speaker: Jay W. Shin?The past, present, and prospective of HCA Asia

?

Overview of meeting (State mission and goals)

Ponpan Matangkasombut Choopong

Varodom Charoensawan

?

Keynote Lecture 1

Chair:?Ponpan Matangkasombut Choopong

Keynote: Shyam Prabhakar?Asian Immune Diversity Atlas and the HCA Genetic Diversity Network

?

Plenary Session 1 - Building Cell Atlases

Session Chairs: Shyam Prabhakar and Anunya Opasawatchai

1.?Jimmie Ye?Exponentiating single cell sequencing

2.?Jonathan Yuin Han Loh?Deciphering Cell-fate Transition at Single-cell Resolution

3.?Jong-Eun Park?Lessons from 1000 cancer single-cell data

4.?Christine Wells?Pluripotent stem cell models of human macrophage diversity

5.?Chung-Chau Hon??A single-cell atlas of transcribed cis-regulatory elements revealed disease associated regulatory modules in distinct cell populations

?

Plenary Session 2 - Infectious and immune mediated diseases

Session Chairs: Senjuti Saha and Waradon Sungnak

1.?Kerstin Meyer?Spatial atlasing reveals an airway associated immune niche

2.?Murim Choi?COVID-eQTL: Genetic dissection of COVID-19 susceptibility

3.?Hamish King?Single-cell genomics to map immune cell states and predict cellular etiology of autoimmune risk loci

4.?Regina Hoo?A single-cell multilineage map of infection during early human placentation reveals unique responses to pathogens

5.?Ryuya Edahiro??Large-scale single-cell RNA-sequencing in Japanese identified biological and host genetic involvement of innate immune cells in COVID-19 severity

?

Plenary Session 3 - Technology and analysis

Session Chairs: Christine Wells and Yukinori Okada

1.?Yutaka Suzuki?Towards understanding immune cell diversity in healthy individuals: single cell analysis of Kashiwa cohort

2.?Rio Sugimura (virtual)??Spatiotemporal gene expression landscape of human embryonic organoids

3.?Weibin Liu?Single-cell Stereo-seq reveals induced progenitor cells involved in axolotl brain regeneration

4.?Dongsung Lee?Simultaneous profiling of 3D genome structure and DNA methylation in single human cells

5.?Lan Jiang (virtual)??Droplet microfluidics based combinatorial indexing for massive-scale 5’-end single-cell RNA sequencing

6.?Irene Papatheodorou (virtual)?Single Cell Expression Atlas

?

Keynote Lecture 2

Chair: Varodom Charoensawan

Keynote: Sarah Teichmann (virtual)?Mapping the human body?one cell at a time

?

Day 2: November 4

Keynote Lecture 3

Chair: Jay W. Shin

Keynote: Alex Shalek (virtual)?Does cancer cell state matter?

?

Plenary Session 4-1 - Equity and Collaboration

Session Chairs: Partha Majumder and Jay W. Shin

1.?HCA Africa: Collins Morang'a?Experiences and lessons learned from organizing HCA Africa?

2.?HCA Latin America: Patricia Severino?Capacity Building through Collaborative Networks for Single-Cell Analysis: The Latin American Experience

3.?CZI: Norbert Tavares?Updates from CZI on progress towards the atlas first draft

?

Plenary Session 4-2 - HCA Asia Flagship Projects

Session Chair: Jay W. Shin

1.?Asian Cancer Cell Atlas: Woong-Yang Park, Yutaka Suzuki, Ankur Sharma and Natini Jinawath

2.?Infectious Disease: Waradon Sungnak and Yukinori Okada?

3.?Microbiome: Archita Mishra

4.?Full-length cDNA: Alistair Forrest?

5.?Single-cell GTEX: Shyam Prabhakar

?

Plenary Session 5 - Non-infectious diseases and cancer

Session Chairs: Natini Jinawath and Angela Wu

1.?Zemin Zhang (virtual)?Comparative analysis of the tumor microenvironment across cancer types

2.?Mu He (virtual)??From one to many: the making of multi-ciliated cells

3.?Dean Thumkeo?Elucidation of the role of PGE2-EP2/4 pathway in cancer immunity utilizing scRNA-seq technology

4.?Yiqun Elaine Cao?Single-cell data analysis for establishing trajectories of CD8+ T cell dysfunction and discovering key modulators

?

Plenary Session 6 - Medical impacts

Session Chairs: Woong-Yang Park and Bhoom Suktitipat

1.?Archita Mishra?Human microbial-immune priming in early life

2.?Manop Pithukpakorn?Reference Transcriptomes: Filling the Gap in Precision Medicine

3.?Yosuke Togashi (virtual)?Clonal evolution in the?tumor microenvironment

4.?Seung Hee Hong?Unraveling the Heterogeneity of Autoimmunity at Single Cell level

5.?Inkyung Jung?Characterization of altered molecular mechanisms in Parkinson’s disease through single-cell multi-omics analyses?

6.?Partha P. Mahumder?Single-Cell Transcriptomic Analysis of Oral Cancer Reveals Two Dominant Cellular Programs

?

General Discussion

Moderators: Christine Wells?and Vimvara Vacharathit

?

Meeting Summary and Closing Remarks

Ponpan Matangkasombut Choopong

Varodom Charoensawan