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磷脂PEG衍生物DSPE-PEG-AC,磷脂-聚乙二醇-炔基

2023-10-25 15:33 作者:kaixin生物  | 我要投稿

英文名稱:DSPE-PEG-AC,DSPE-PEG-Acrylate

English name:AC-PEG-DSPE,Acrylate-PEG-DSPE

中文名稱:磷脂-聚乙二醇-炔基

Chinese name:磷脂-PEG-炔基

Acrylate-PEG-DSPE,一種磷脂PEG衍生物,用于脂質(zhì)體制備,磷脂化聚乙二醇結(jié)合具有親水性和疏水性,聚乙二醇磷脂脂質(zhì)體形成優(yōu)質(zhì)材料,能夠用于medicinal輸送、基因轉(zhuǎn)染和疫苗傳遞。聚乙二醇化磷脂可以明顯的改善blood circulation時(shí)間和穩(wěn)定封裝medicinal。丙烯酸酯功能化PEG是制備生物相容性和生物可降解水凝膠及其它生物聚合物的常用聚合物。

Acrylate-PEG-DSPE, a phospholipid PEG derivative, is used for lipid preparation. Phosphatidylated polyethylene glycol binding has hydrophilicity and hydrophobicity. Polyethylene glycol phospholipid liposomes form high-quality materials that can be used for medical delivery, gene transfection, and vaccine delivery. Polyethylene glycol phospholipids can significantly improve the blood circulation time and stabilize the packaging of medical. Acrylate functionalized PEG is a common polymer for preparing biocompatible and biodegradable hydrogels and other biopolymers。

1,2-二硬脂?;?sn-甘油-3-磷酸乙酰胺-聚乙二醇是一種PEG修飾的脂質(zhì)。它是一種長循環(huán)的脂質(zhì)體膜,在水分散體中形成膠束,表面活性劑的臨界膠束濃度(CMC)比低102倍,因此medicinal穩(wěn)定性更好,即使通過blood稀釋,也能保持膠束顆粒的完整性,具有一定的靶向性,丙烯酸酯可以自聚合,也可以與其他單體共聚。它是一種用于制造粘合劑、合成樹脂、特種橡膠和塑料的單體。

1,2-distearoyl-sn-glycerol-3-phosphoacetamide-polyethylene glycol is a PEG modified lipid. It is a long circulating liposome membrane that forms micelles in aqueous dispersions. The critical micelle concentration (CMC) of surfactants is 102 times lower, making it more stable. Even if diluted by blood, it can maintain the integrity of micelle particles and has a certain degree of targeting. Acrylates can self polymerize and copolymerize with other monomers. It is a monomer used in the manufacture of adhesives, synthetic resins, special rubbers, and plastics.

功能化的聚乙二醇可以用來修飾蛋白質(zhì),肽和材料,也可以增加溶解度和穩(wěn)定性,降低多肽和蛋白質(zhì)免疫原性。它還可以抑制帶電分子非特異性結(jié)合體去修飾表面。該產(chǎn)品可應(yīng)用于醫(yī)學(xué)研究,medicinal釋放,納米技術(shù)和新材料研究,細(xì)胞培養(yǎng)。以及配體研究,多肽合成支持,接枝高分子化合物,新材料和聚乙二醇改性功能涂層等活性化合物方面。?

Functionalized polyethylene glycol can be used to modify proteins, peptides, and materials, as well as increase solubility and stability, reducing the immunogenicity of polypeptides and proteins. It can also inhibit the non specific binding of charged molecules to modify the surface. This product can be used in medical research, medical release, nanotechnology and new material research, and cell culture. And ligand research, peptide synthesis support, grafting polymer compounds, new materials, and polyethylene glycol modified functional coatings and other active compounds.

MV:可定制,磷脂-PEG 1-炔基、DSPE-PEG 2-AC,磷脂-聚乙二醇 3.4-炔基、DSPE-PEG 10-Acrylate、DSPE-聚乙二醇 20-Acrylate、磷脂-peg 5-炔基

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