HRP（Horse radish Peroxidase，辣根過氧化物酶）是一種含亞鐵血紅素的蛋白質(zhì)，廣泛分布于植物界，它是由無色的酶蛋白和棕色的鐵卟啉結(jié)合而成的糖蛋白，糖含量18%，分子量達(dá)44000 kDa。HRP易提取、價格低廉、性質(zhì)穩(wěn)定，耐熱及有機(jī)溶劑，與抗原或一抗偶聯(lián)后，活性很少受損失，在免疫學(xué)實(shí)驗中廣泛應(yīng)用。

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艾美捷/HRP標(biāo)記小鼠抗猴IgG二抗概述：

克隆：SB108a

同型：小鼠（BALB/c）IgG1k

免疫原：Rhesus IgG

特異性：Rhesus and cynomolgus IgG

對人和兔免疫球蛋白、山羊IgG和小鼠、大鼠、倉鼠、豚鼠的最低反應(yīng)性，綿羊、驢、牛、馬、豬、貓和雞血清。

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艾美捷/HRP標(biāo)記小鼠抗猴IgG二抗應(yīng)用:

ELISA–質(zhì)量檢測1-8

FLISA–經(jīng)過質(zhì)量測試

FC——文獻(xiàn)9報道

WB——文獻(xiàn)10中有報道

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HRP標(biāo)記小鼠抗猴IgG二抗其他應(yīng)用：由于應(yīng)用不同，需要確定所使用產(chǎn)品的最/佳工作稀釋度匹配需求。

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HRP標(biāo)記小鼠抗猴IgG二抗文獻(xiàn)參考：

1. Kasturi SP, Skountzou I, Albrecht RA, Koutsonanos D, Hua T, Nakaya HI, et al. Programming the magnitude and persistence of antibody responseswith innate immunity. Nature. 2011;470:543-7. (ELISA)

2. Wang J, Tricoche N, Du L, Hunter M, Zhan B, Goud G, et al. The adjuvanticity of an O.volvulus-derived rOv-ASP-1 protein in mice using sequential?vaccinations and in non-human primates. PLoS One. 2012;7(5):e37019. (ELISA)

3. Ferraro B, Talbott KT, Balakrishnan A, Cisper N, Morrow MP, Hutnick NA, et al. Inducing?humoral and cellular responses to multiple sporozoite and?liver-stage malaria antigens using exogenous plasmid DNA. Infect Immun. 2013;81:3709-20. (ELISA)

4. Padte NN, Boente-Carrera M, Andrews CD, McManus J, Grasperge BF, Gettie A, et al. A glycolipid adjuvant, 7DW8-5, enhances CD8+ T cell?responses induced by an adenovirus-vectored malaria vaccine in non-human primates. PLoS One. 2013;8(10):e78407. (ELISA)

5. Sholukh AM, Watkins JD, Vyas HK, Gupta S, Lakhashe SK, Thorat S, et al. Defense-in-depth by mucosally administered anti-HIV dimeric IgA2 and?systemic IgG1 mAbs: complete protection of rhesus monkeys from mucosal SHIV challenge. Vaccine. 2015;33:2086-95. (ELISA)

6. Bolton DL, Pegu A, Wang K, McGinnis K, Nason M, Foulds K, et al. Human immunodeficiency virus type 1 monoclonal antibodies suppress acute?simian-human immunodeficiency virus viremia and limit seeding of cell-associated viral reservoirs. J Virol. 2015;90:1321-32. (ELISA)

7. Yang Z, Wang H, Salcedo TW, Suchard SJ, Xie JH, Schneeweis LA, et al. Integrated pharmacokinetic/pharmacodynamic analysis for determining the?minimal anticipated biological effect level of a novel anti-CD28 receptor antagonist BMS-931699. J Pharmacol Exp Ther. 2015;355:506-15. (ELISA)

8. Kutzler MA, Wise MC, Hutnick NA, Moldoveanu Z, Hunter M, Reuter MA, et al. Chemokine-adjuvanted electroporated DNA vaccine induces?substantial protection from simian immunodeficiency virus vaginal challenge. Mucosal Immunol. 2016;9:13-23. (ELISA)

9. Guo J, Zuo T, Cheng L, Wu X, Tang J, Sun C, et al. Simian immunodeficiency virus infection evades vaccine-elicited antibody responses to V2 region.?J Acquir Immune Defic Syndr. 2015;68:502-10. (FC)

10. Parks CL, Koff WC, inventors; International AIDS Vaccine Initiative, assignee. Transgenic Vero-CD4-CCR5 cell line. United States patent applicaton?publication US 2017/0266272 A1. 2017 Sep21. (WB)

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艾美捷科技是SouthernBiotech的中國代理商，為科研工作者提供優(yōu)質(zhì)的HRP標(biāo)記小鼠抗猴IgG二抗。