去硫球蛋白是一種單環(huán)、無硫的生物素類似物，與鏈霉親和素結(jié)合的特異性幾乎相同，但親和力低于生物素（Kd=1011vs.1015m）。因此，基于與游離生物素競爭置換的溫和條件，脫巰基化蛋白質(zhì)可以很容易且特別地從鏈霉親和素樹脂中洗脫出來。對(duì)于生物樣品的下拉實(shí)驗(yàn)，去硫球蛋白的這種軟釋放特性也有助于減少內(nèi)源性生物素化分子的共純化，這些分子在用游離生物素洗脫目標(biāo)蛋白復(fù)合物時(shí)仍與鏈霉親和素結(jié)合。

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產(chǎn)品名稱：脫硫生物素-PEG4-二苯并環(huán)辛烯

英文名稱：Desthiobiotin-PEG4-DBCO

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CAS:2032788-37-5

外觀：固體/粉末

分子式：C39H51N5O8

分子量：719.87

溶解性：Water, DMSO, DMF

規(guī)格：mg

質(zhì)量純度：95%+

儲(chǔ)存條件：-20℃

儲(chǔ)存時(shí)間：1年

產(chǎn)地：西安

用途：僅用于科研實(shí)驗(yàn)

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西安瑞禧生物實(shí)驗(yàn)室可自主生產(chǎn)銷售各類DBCO點(diǎn)擊化學(xué)偶連小分子、高分子以及一些定制類的DBCO點(diǎn)擊化學(xué)產(chǎn)品,瑞禧生物還可制備一些DBCO修飾的多肽，核酸，多糖 單糖 寡糖以及蛋白等不同產(chǎn)品。

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以上資料來自小編YQ2020.12