人偏肺病毒感染是人體感染人偏肺病毒（humanmetapneumovirus，hMPV）后引起的一種急性呼吸道傳染病，全年散發(fā)，多發(fā)生于冬末及春初。

貨號：RVV22901

產(chǎn)品鏈接：http://www.antibodysystem.com/product/13692.html

寄主物種：Human

物種反應性：Human metapneumovirus

形式：Liquid

存儲緩沖區(qū)：0.01M PBS, pH 7.4.

濃度：1 mg/ml

純度：>95% by SDS-PAGE.

克隆性：Monoclonal

種型：IgG1

應用：Neut

儲存：Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -80°C long term.

參考文獻：

Low-pH triggering of human metapneumovirus fusion: essential residues and importance in entry. PMID: 19036821
Genetic diversity and molecular evolution of the major human metapneumovirus surface glycoproteins over a decade. PMID: 24041471
Genetic diversity and evolution of human metapneumovirus fusion protein over twenty years. PMID: 19740442
Phylogenetic analysis of human metapneumovirus among children with acute respiratory infections in Kuala Lumpur, Malaysia. PMID: 25382484

Transmembrane Domain Dissociation Is Required for Hendra Virus F Protein Fusogenic Activity. PMID: 31462574
Development of liposomes and pseudovirions with fusion activity for efficient gene delivery. PMID: 22023472
Molecular Features of the Measles Virus Viral Fusion Complex That Favor Infection and Spread in the Brain. PMID: 34061592
Mutations in the parainfluenza virus 5 fusion protein reveal domains important for fusion triggering and metastability. PMID: 24089572
The electrophysiological net response ('F-complex') to spatial fusion of speech elements forming an auditory object. PMID: 12738428
Identification of residues in the human respiratory syncytial virus fusion protein that modulate fusion activity and pathogenesis. PMID: 25339762
Triggering of the newcastle disease virus fusion protein by a chimeric attachment protein that binds to Nipah virus receptors. PMID: 21460213
A Randomized Control Trial Comparing Local Autografts and Allografts in Single Level Anterior Cervical Discectomy and Fusion Using a Stand-Alone Cage. PMID: 33189111
The 'F-complex' and MMN tap different aspects of deviance. PMID: 15661112
Cytogenetic mapping of the Muller F element genes in Drosophila willistoni group. PMID: 25134938

hMPV屬于肺炎病毒科，偏肺病毒屬，為有包膜的單股負鏈RNA病毒，平均直徑大約200nm。hMPV包括A和B兩個基因型，可分為A1、A2、B1、B2四個亞型，這些亞型常常同時流行，各亞型病毒傳播力和致病性未見明顯差別。

hMPV對熱敏感，60℃?30分鐘可滅活；對乙醚、氯仿等有機溶劑敏感；1%次氯酸鈉等含氯消毒劑、5%福爾馬林、2%戊二醛、1%碘伏等常用消毒劑可滅活病毒；對0.1%脫氧膽酸鈉、十二烷基硫酸鈉（SDS）和曲拉通X-100（TritonX-100）等去污劑敏感。

HMPV屬于肺病毒科，偏肺病毒屬，有包膜的單股負鏈RNA病毒。2001年，由荷蘭學者首次從未知病原體引起呼吸道感染患兒的鼻咽抽吸物樣本中檢出。血清學研究表明其存在至少60年，在世界各地均有分布，是常見呼吸道病原體之一。

HMPV主要通過咳嗽和打噴嚏產(chǎn)生的飛沫或氣溶膠傳播，與感染者密切接觸和接觸病毒污染的環(huán)境也可能造成傳播。一般來說，感染后潛伏期約3-5天，HMPV誘發(fā)的免疫保護較弱，反復感染常見。HMPV全年均有檢出，但以冬春季檢出率最高。此外，HMPV感染也可以引起暴發(fā)流行。