口服藥物吸收模型的研究進(jìn)展 莫李立，王素軍?

摘要: 對(duì)口服藥物吸收模型進(jìn)行綜述，介紹各模型的研究方法、特點(diǎn)和應(yīng)用進(jìn)展，為藥物吸收的科學(xué)評(píng)價(jià) 提供參考。 關(guān)鍵詞: 口服藥物; 腸道吸收; 人工生物膜; 細(xì)胞模型; 灌流模型?

Abstract: Based on investigation of the domestic and foreign relevant literatures published in recent years，the progresses on oral drug absorption models were reviewed． The experimental methods，the characteristics and application progress of oral drug absorption models were introduced to provide a reference for the scientific evaluation of drug absorption． Key words: oral drug; intestinal absorption; artificial biomembrane; cell modle; perfusion modle