聲明：本專(zhuān)欄主要對(duì)生命科學(xué)領(lǐng)域的一些期刊文章標(biāo)題進(jìn)行翻譯，所有內(nèi)容均由本人手工整理翻譯。由于本人專(zhuān)業(yè)為生物分析相關(guān)，其他領(lǐng)域如果出現(xiàn)翻譯錯(cuò)誤請(qǐng)諒解。

1.How low can you go? Air pollution affects mortality at very low levels.

你能做到多低？空氣污染在很低的水平上就會(huì)影響死亡率。

2.Losing the battle over best-science guidance early in a crisis: COVID-19 and beyond.

在危機(jī)初期失去最佳科學(xué)指導(dǎo)的戰(zhàn)斗：?COVID-19及以后。

3.COVID-19 Exposure Assessment Tool (CEAT): Exposure quantification based on ventilation, infection prevalence, group characteristics, and behavior.

COVID-19暴露評(píng)估工具（CEAT）：?基于通風(fēng)、感染率、群體特征和行為的暴露量化。

4.Orientation pinwheels in primary visual cortex of a highly visual marsupial.

一種高度視覺(jué)的有袋動(dòng)物初級(jí)視覺(jué)皮層中的方向針輪。

5.A cerebellar-prepontine circuit for tonic immobility triggered by an inescapable threat.

由不可避免的威脅引發(fā)的小腦-前庭回路的強(qiáng)直不動(dòng)。

6.Neurons burdened by DNA double-strand breaks incite microglia activation through antiviral-like signaling in neurodegeneration.

受DNA雙鏈斷裂影響的神經(jīng)元在神經(jīng)退行性疾病中通過(guò)類(lèi)似抗病毒的信號(hào)來(lái)煽動(dòng)小膠質(zhì)細(xì)胞的激活。

7.The long noncoding RNA mimi scaffolds neuronal granules to maintain nervous system maturity.

長(zhǎng)非編碼RNA mimi為神經(jīng)元顆粒提供支架以維持神經(jīng)系統(tǒng)的成熟。

8.Ca2+ channels couple spiking to mitochondrial metabolism in substantia nigra dopaminergic neurons.

黑質(zhì)多巴胺能神經(jīng)元中的Ca2+通道與線粒體代謝相聯(lián)系。

9.Astrocytic NDRG2-PPM1A interaction exacerbates blood-brain barrier disruption after subarachnoid hemorrhage.

星形細(xì)胞NDRG2-PM1A的相互作用加劇了蛛網(wǎng)膜下腔出血后血腦屏障的破壞。

10.RNF220 is an E3 ubiquitin ligase for AMPA receptors to regulate synaptic transmission.

RNF220是AMPA受體的E3泛素連接酶，用于調(diào)節(jié)突觸傳遞。

11.Inherent tendency of Synechococcus and heterotrophic bacteria for mutualism on long-term coexistence despite environmental interference.

盡管有環(huán)境干擾，共生菌和異養(yǎng)菌在長(zhǎng)期共存上的固有傾向。

12.Disease resistance in coral is mediated by distinct adaptive and plastic gene expression profiles.

珊瑚的抗病性是由不同的適應(yīng)性和可塑性基因表達(dá)譜介導(dǎo)的。

13.Postglacial species arrival and diversity buildup of northern ecosystems took millennia.

冰川期后物種的到來(lái)和北方生態(tài)系統(tǒng)的多樣性積累需要數(shù)千年的時(shí)間。

14.Constraining the formation and transport of lunar impact glasses using the ages and chemical compositions of Chang’e-5 glass beads.

利用嫦娥五號(hào)玻璃珠的年齡和化學(xué)成分制約月球撞擊玻璃的形成和運(yùn)輸。

15.Daytime SO2 chemistry on ubiquitous urban surfaces as a source of organic sulfur compounds in ambient air.

無(wú)處不在的城市表面的白天SO2化學(xué)成分是環(huán)境空氣中有機(jī)硫化合物的來(lái)源。

16.Tailoring centripetal metamaterial with superelasticity and negative Poisson’s ratio for organic solvents adsorption.

定制具有超彈性和負(fù)泊松比的向心超材料用于有機(jī)溶劑的吸附。

17.Neurorobotic approaches to emulate human motor control with the integration of artificial synapse.

模仿人類(lèi)運(yùn)動(dòng)控制的神經(jīng)機(jī)器人方法與人工突觸的整合。

18.Atomic-scale imaging of emergent order at a magnetic field–induced Lifshitz transition.

磁場(chǎng)誘導(dǎo)的Lifshitz轉(zhuǎn)變中出現(xiàn)的秩序的原子尺度成像。

19.Injection continuous liquid interface production of 3D objects.

三維物體的注射連續(xù)液體界面生產(chǎn)。

20.Designing interphases for practical aqueous zinc flow batteries with high power density and high areal capacity.

為具有高功率密度和高面積容量的實(shí)用鋅流電池設(shè)計(jì)相位。

21.Pattern recognition with neuromorphic computing using magnetic field–induced dynamics of skyrmions.

利用磁場(chǎng)誘導(dǎo)的天體動(dòng)力學(xué)的模式識(shí)別與神經(jīng)形態(tài)計(jì)算。

22.Optically controllable magnetism in atomically thin semiconductors.

原子薄半導(dǎo)體中的光學(xué)可控磁性。

23.An “inverse” harpoon mechanism.

一種?"反?"魚(yú)叉機(jī)制。

24.A wave-confining metasphere beamforming acoustic sensor for superior human-machine voice interaction.

一種用于高級(jí)人機(jī)語(yǔ)音交互的波導(dǎo)元球波束成形聲學(xué)傳感器。

25.Modular derivation of diverse, regionally discrete human posterior CNS neurons enables discovery of transcriptomic patterns.

不同的、區(qū)域性的人類(lèi)中樞神經(jīng)系統(tǒng)后部神經(jīng)元的模塊化推導(dǎo)使轉(zhuǎn)錄組模式得到發(fā)現(xiàn)。

26.Microfluidic affinity selection of active SARS-CoV-2 virus particles.

活性SARS-CoV-2病毒顆粒的微流控親和選擇。

27.Accurate detection of benign and malignant renal tumor subtypes with MethylBoostER: An epigenetic marker–driven learning framework.

用MethylBoostER精確檢測(cè)良性和惡性腎臟腫瘤亞型：一個(gè)表觀遺傳標(biāo)記物驅(qū)動(dòng)的學(xué)習(xí)框架。

28.CAR density influences antitumoral efficacy of BCMA CAR T cells and correlates with clinical outcome.

CAR密度影響B(tài)CMA CAR T細(xì)胞的抗腫瘤療效并與臨床結(jié)果相關(guān)。

29.Circadian disruption enhances HSF1 signaling and tumorigenesis in Kras-driven lung cancer.

晝夜節(jié)律紊亂增強(qiáng)了Kras驅(qū)動(dòng)的肺癌中HSF1的信號(hào)傳導(dǎo)和腫瘤發(fā)生。

30.In vivo peptide-based delivery of a gene-modifying enzyme into cells of the central nervous system.

基于肽的基因修飾酶的體內(nèi)遞送到中樞神經(jīng)系統(tǒng)的細(xì)胞中。

31.Sex-specific epigenetic development in the mouse hypothalamic arcuate nucleus pinpoints human genomic regions associated with body mass index.

小鼠下丘腦弓形核的性別特異性表觀遺傳學(xué)發(fā)展確定了與體重指數(shù)相關(guān)的人類(lèi)基因組區(qū)域。

32.Regulation of autoimmune disease progression by Pik3ip1 through metabolic reprogramming in T cells and therapeutic implications.

Pik3ip1通過(guò)T細(xì)胞的代謝重編程對(duì)自身免疫性疾病進(jìn)展的調(diào)節(jié)及治療意義。

33.Cancer cells produce liver metastasis via gap formation in sinusoidal endothelial cells through proinflammatory paracrine mechanisms.

癌細(xì)胞通過(guò)竇道內(nèi)皮細(xì)胞的間隙形成，通過(guò)促炎癥的旁分泌機(jī)制產(chǎn)生肝轉(zhuǎn)移。

34.Edge modification facilitated heterogenization and exfoliation of two-dimensional nanomaterials for cancer catalytic therapy.

邊緣修飾促進(jìn)了用于癌癥催化治療的二維納米材料的異質(zhì)化和剝落。

35.Cell clusters adopt a collective amoeboid mode of migration in confined nonadhesive environments.

細(xì)胞團(tuán)在封閉的非粘附環(huán)境中采用集體阿米巴模式遷移。

36.Mitochondrial pyruvate supports lymphoma proliferation by fueling a glutamate pyruvate transaminase 2–dependent glutaminolysis pathway.

線粒體丙酮酸通過(guò)助長(zhǎng)谷氨酸丙酮酸轉(zhuǎn)氨酶2依賴(lài)的谷氨酰胺分解途徑支持淋巴瘤增殖。

37.Therapeutic implications of mitochondrial stress–induced proteasome inhibitor resistance in multiple myeloma.

多發(fā)性骨髓瘤中線粒體應(yīng)激引起的蛋白酶體抑制劑耐藥的治療意義。

38.Cryo-EM reveals a mechanism of USP1 inhibition through a cryptic binding site.

Cryo-EM揭示了通過(guò)隱性結(jié)合位點(diǎn)抑制USP1的機(jī)制。

39.Erratum for the Research Article: “Full-Nitro-Nitroamino Cooperative Action: Climbing the Energy Peak of Benzenes with Enhanced Chemical Stability” by Sun et al..

研究文章的更正："全硝基-硝基胺合作行動(dòng)：?攀登苯的能量峰，增強(qiáng)化學(xué)穩(wěn)定性"，作者Sun等人。

40.Bayesian analyses of direct radiocarbon dates reveal geographic variations in the rate of rice farming dispersal in prehistoric Japan.

對(duì)直接放射性碳素日期的貝葉斯分析揭示了史前日本水稻種植擴(kuò)散速度的地理差異。

41.Best frequencies and temporal delays are similar across the low-frequency regions of the guinea pig cochlea.

豚鼠耳蝸各低頻區(qū)的最佳頻率和時(shí)間延遲是相似的。

42.An in situ study of abyssal turbidity-current sediment plumes generated by a deep seabed polymetallic nodule mining preprototype collector vehicle.

深海海底多金屬結(jié)核開(kāi)采預(yù)型采集車(chē)產(chǎn)生的深海濁流沉積物羽流的現(xiàn)場(chǎng)研究。

43.Wide-angle seismic reflections reveal a lithosphere-asthenosphere boundary zone in the subducting Pacific Plate, New Zealand.

廣角地震反射揭示了新西蘭俯沖太平洋板塊的巖石圈-巖石圈邊界區(qū)。

44.Geographically resolved social cost of anthropogenic emissions accounting for both direct and climate-mediated effects.

考慮到直接影響和氣候介導(dǎo)的影響，從地理上解決了人為排放的社會(huì)成本。

45.Catastrophic growth of totally molten magma chambers in months to years.

完全熔融的巖漿室在幾個(gè)月到幾年內(nèi)的災(zāi)難性增長(zhǎng)。

46.Bridging time scales of faulting: From coseismic to postseismic slip of the Mw 6.0 2014 South Napa, California earthquake.

彌合斷層的時(shí)間尺度：2014年加州南納帕Mw6.0地震從震中到震后的滑動(dòng)。

47.Reduced dopant-induced scattering in remote charge-transfer-doped MoS2 field-effect transistors.

遠(yuǎn)程電荷轉(zhuǎn)移摻雜的MoS2場(chǎng)效應(yīng)晶體管中摻雜劑誘導(dǎo)散射的減少。

48.Self-aligned patterning technique for fabricating high-performance diamond sensor arrays with nanoscale precision.

用于制造具有納米級(jí)精度的高性能金剛石傳感器陣列的自對(duì)準(zhǔn)圖案技術(shù)。

49.Kinetics of laser-induced melting of thin gold film: How slow can it get?.

激光誘導(dǎo)熔化薄金膜的動(dòng)力學(xué)：?它能變得多慢？

50.Influence of voids on the thermal and light stability of perovskite solar cells.

空隙對(duì)包晶石太陽(yáng)能電池的熱穩(wěn)定性和光穩(wěn)定性的影響.

51.Selective dehydrogenation of small and large molecules by a chloroiridium catalyst.

氯銥合金催化劑對(duì)大、小分子的選擇性脫氫作用。

52.Lattice strain modulation toward efficient blue perovskite light-emitting diodes.

面向高效藍(lán)色包晶石發(fā)光二極管的晶格應(yīng)變調(diào)控。

53.Addressing gain-bandwidth trade-off by a monolithically integrated photovoltaic transistor.

通過(guò)單片集成光伏晶體管解決增益-帶寬折衷問(wèn)題。

54.Optical gradient force on chiral particles.

手性粒子上的光學(xué)梯度力。

55.Spin homojunction with high interfacial transparency for efficient spin-charge conversion.

高效自旋電荷轉(zhuǎn)換的高界面透明度的自旋同質(zhì)結(jié)。

56.Electrochemiluminescence in paired signal electrode (ECLipse) enables modular and scalable biosensing.

成對(duì)信號(hào)電極的電化學(xué)發(fā)光（ECLipse）實(shí)現(xiàn)了模塊化和可擴(kuò)展的生物感應(yīng)。

57.Wearable microneedle-based electrochemical aptamer biosensing for precision dosing of drugs with narrow therapeutic windows.

基于微針的可穿戴式電化學(xué)誘導(dǎo)劑生物傳感，用于治療窗口狹窄的藥物的精確劑量。

58.Single-crystal organometallic perovskite optical fibers.

單晶有機(jī)金屬過(guò)氧化物光導(dǎo)纖維。

59.Tunable topological Dirac surface states and van Hove singularities in kagome metal GdV6Sn6.

可調(diào)控的拓?fù)涞依吮砻鎽B(tài)和卡果美金屬GdV6Sn6中的范霍夫奇異點(diǎn)。

60.The genetic architecture of phenotypic diversity in the Betta fish (Betta splendens).

貝塔魚(yú)（Betta splendens）表型多樣性的遺傳結(jié)構(gòu)。

61.Apolipoprotein E mediates cell resistance to influenza virus infection.

載脂蛋白E介導(dǎo)細(xì)胞對(duì)流感病毒感染的抵抗。

62.Semirational bioengineering of AAV vectors with increased potency and specificity for systemic gene therapy of muscle disorders.

具有更高效力和特異性的AAV載體的Semirational?生物工程，用于肌肉疾病的系統(tǒng)性基因治療。

63.PD-1/PD-L1 blockade abrogates a dysfunctional innate-adaptive immune axis in critical β-coronavirus disease.

PD-1/PD-L1阻斷法廢除臨界β-冠狀病毒疾病中先天適應(yīng)性免疫軸的功能障礙。

64.PKM2 promotes pulmonary fibrosis by stabilizing TGF-β1 receptor I and enhancing TGF-β1 signaling.

PKM2通過(guò)穩(wěn)定TGF-β1受體I和增強(qiáng)TGF-β1信號(hào)傳導(dǎo)促進(jìn)肺纖維化。

65.Gene drive mosquitoes can aid malaria elimination by retarding Plasmodium sporogonic development.

基因驅(qū)動(dòng)蚊子可以通過(guò)延緩瘧原蟲(chóng)的孢子期發(fā)育來(lái)幫助消除瘧疾。

66.A single intravenous injection of cyclosporin A–loaded lipid nanocapsules prevents retinopathy of prematurity.

單次靜脈注射環(huán)孢素A負(fù)載的脂質(zhì)納米膠囊可預(yù)防早產(chǎn)兒視網(wǎng)膜病。

67.SARS-CoV-2 disrupts respiratory vascular barriers by suppressing Claudin-5 expression.

SARS-CoV-2通過(guò)抑制Claudin-5的表達(dá)破壞了呼吸道血管屏障。

68.The structure of a polyketide synthase bimodule core.

聚酮體合成酶雙模塊核心的結(jié)構(gòu)。

69.Self-assembling peptide nanofiber HIV vaccine elicits robust vaccine-induced antibody functions and modulates Fc glycosylation.

自組裝多肽納米纖維HIV疫苗引發(fā)強(qiáng)大的疫苗誘導(dǎo)抗體功能并調(diào)節(jié)Fc糖基化。

70.The coral Acropora loripes genome reveals an alternative pathway for cysteine biosynthesis in animals.

珊瑚Acropora loripes的基因組揭示了動(dòng)物中半胱氨酸生物合成的替代途徑。

71.Organoid-on-a-chip model of human ARPKD reveals mechanosensing pathomechanisms for drug discovery.

人類(lèi)ARPKD的類(lèi)器官芯片模型揭示了藥物研發(fā)的機(jī)械感應(yīng)病理機(jī)制。

72.The adipocyte-enriched secretory protein tetranectin exacerbates type 2 diabetes by inhibiting insulin secretion from β cells.

富含脂肪細(xì)胞的分泌蛋白tetranectin通過(guò)抑制β細(xì)胞的胰島素分泌而加劇了2型糖尿病。

73.Systemic antibody responses against human microbiota flagellins are overrepresented in chronic fatigue syndrome patients.

針對(duì)人類(lèi)微生物群鞭毛蛋白的系統(tǒng)性抗體反應(yīng)在慢性疲勞綜合征患者中占比過(guò)高。

74.FBXO42 facilitates Notch signaling activation and global chromatin relaxation by promoting K63-linked polyubiquitination of RBPJ.

FBXO42通過(guò)促進(jìn)RBPJ的K63連接的多泛素化促進(jìn)Notch信號(hào)的激活和全球染色質(zhì)的放松。

75.Rhomboid-catalyzed intramembrane proteolysis requires hydrophobic matching with the surrounding lipid bilayer.

Rhomboid催化的膜內(nèi)蛋白分解需要與周?chē)|(zhì)雙分子層的疏水匹配。

76.Islet primary cilia motility controls insulin secretion.

胰島初級(jí)纖毛的運(yùn)動(dòng)控制著胰島素的分泌。

77.Cryo–electron microscopy unveils unique structural features of the human Kir2.1 channel.

冷凍電子顯微鏡揭示了人類(lèi)Kir2.1通道的獨(dú)特結(jié)構(gòu)特征。

78.Role for N-glycans and calnexin-calreticulin chaperones in SARS-CoV-2 Spike maturation and viral infectivity.

N-糖和Calnexin-calreticulin伴侶在SARS-CoV-2穗狀體成熟和病毒感染性中的作用。

79.Inhibition of Chk2 promotes neuroprotection, axon regeneration, and functional recovery after CNS injury.

抑制Chk2促進(jìn)中樞神經(jīng)系統(tǒng)損傷后的神經(jīng)保護(hù)、軸突再生和功能恢復(fù)。

80.Brain lipidomics: From functional landscape to clinical significance.

腦脂質(zhì)組學(xué)：?從功能景觀到臨床意義。

81.Environmental risks from artificial nighttime lighting widespread and increasing across Europe.

人工夜間照明帶來(lái)的環(huán)境風(fēng)險(xiǎn)在整個(gè)歐洲普遍存在并不斷增加。

82.Global seaweed productivity.

全球海藻生產(chǎn)力。

83.Ambush predation and the origin of euprimates.

埋伏捕食和食肉動(dòng)物的起源。

84.High-pressure synthesis and storage of solid organic compounds in active subduction zones.

活躍俯沖帶中固體有機(jī)化合物的高壓合成和儲(chǔ)存。

85.Compositions of carbonaceous-type asteroidal cores in the early solar system.

早期太陽(yáng)系中碳質(zhì)型小行星核心的構(gòu)成。

86.Temporal gene expression patterns in the coral Euphyllia paradivisa reveal the complexity of biological clocks in the cnidarian-algal symbiosis.

珊瑚Euphyllia paradivisa的時(shí)間基因表達(dá)模式揭示了刺胞-藻類(lèi)共生中生物鐘的復(fù)雜性。

87.The lunar nodal cycle controls mangrove canopy cover on the Australian continent.

月球結(jié)點(diǎn)周期控制著澳大利亞大陸的紅樹(shù)林樹(shù)冠覆蓋。

88.Quantum phase transition dynamics in the two-dimensional transverse-field Ising model.

二維橫場(chǎng)伊辛模型的量子相變動(dòng)力學(xué)。

89.A flexible electronic strain sensor for the real-time monitoring of tumor regression.

用于實(shí)時(shí)監(jiān)測(cè)腫瘤消退的柔性電子應(yīng)變傳感器。

90.Organic electronic transmembrane device for hosting and monitoring 3D cell cultures.

用于承載和監(jiān)測(cè)三維細(xì)胞培養(yǎng)的有機(jī)電子跨膜裝置。

91.Uncovering the molecular mechanism for dual effect of ATP on phase separation in FUS solution.

揭示ATP對(duì)FUS溶液中相分離的雙重影響的分子機(jī)制。

92.Ion slippage through Li+-centered G-quadruplex.

通過(guò)Li+為中心的G-quadruplex的離子滑移。

93.In situ diagnosis and simultaneous treatment of cardiac diseases using a single-device platform.

利用單設(shè)備平臺(tái)對(duì)心臟疾病進(jìn)行現(xiàn)場(chǎng)診斷和同步治療。

94.Scale-reconfigurable miniature ferrofluidic robots for negotiating sharply variable spaces.

用于談判急劇變化空間的可重新配置的微型鐵流體機(jī)器人。

95.Strain propagation in layered two-dimensional halide perovskites.

分層二維鹵化物過(guò)氧化物中的應(yīng)變傳播。

96.Making a case for femto-phono-magnetism with FePt.

用FePt為超小型單磁體做了一個(gè)案例。

97.Observation of robust zero-energy state and enhanced superconducting gap in a trilayer heterostructure of MnTe/Bi2Te3/Fe(Te, Se).

在MnTe/Bi2Te3/Fe(Te, Se)的三層異質(zhì)結(jié)構(gòu)中觀察到強(qiáng)大的零能態(tài)和增強(qiáng)的超導(dǎo)間隙。

98.Nanofloating gate modulated synaptic organic light-emitting transistors for reconfigurable displays.

用于可重構(gòu)顯示的納米浮柵調(diào)制突觸式有機(jī)發(fā)光晶體管。

99.Asymmetric multifunctionalization of alkynes via photo-irradiated organocatalysis.

通過(guò)光輻照有機(jī)催化技術(shù)實(shí)現(xiàn)炔烴的不對(duì)稱(chēng)多功能化。

100.Activation of TrkB-Akt signaling rescues deficits in a mouse model of SCA6.

TrkB-Akt信號(hào)的激活可挽救SCA6小鼠模型的缺陷。

101.“Omics” data unveil early molecular response underlying limb regeneration in the Chinese mitten crab, Eriocheir sinensis.

"Omics "數(shù)據(jù)揭示了中華絨螯蟹（Eriocheir sinensis）肢體再生的早期分子反應(yīng)。

102.Eprenetapopt triggers ferroptosis, inhibits NFS1 cysteine desulfurase, and synergizes with serine and glycine dietary restriction.

Eprenetapopt觸發(fā)了鐵中毒，抑制了NFS1半胱氨酸脫硫酶，并與絲氨酸和甘氨酸的飲食限制協(xié)同作用。

103.The nonconducting W434F mutant adopts upon membrane depolarization an inactivated-like state that differs from wild-type Shaker-IR potassium channels.

非傳導(dǎo)性的W434F突變體在膜去極化時(shí)采用類(lèi)似失活的狀態(tài)，與野生型Shaker-IR鉀通道不同。

104.The emergence of spontaneous coordinated epithelial rotation on cylindrical curved surfaces.

圓柱形曲面上自發(fā)協(xié)調(diào)上皮旋轉(zhuǎn)的出現(xiàn)。

105.Transcription and splicing regulation by NLRC5 shape the interferon response in human pancreatic β cells.

NLRC5的轉(zhuǎn)錄和剪接調(diào)節(jié)塑造了人類(lèi)胰腺β細(xì)胞的干擾素反應(yīng)。

106.An AMPK phosphoregulated RhoGEF feedback loop tunes cortical flow–driven amoeboid migration in vivo.

AMPK磷酸化調(diào)節(jié)的RhoGEF反饋回路調(diào)節(jié)體內(nèi)皮質(zhì)流驅(qū)動(dòng)的變形蟲(chóng)遷移。

107.Differential proinflammatory activities of Spike proteins of SARS-CoV-2 variants of concern.

引起關(guān)注的SARS-CoV-2變體的穗狀蛋白的促炎癥活性差異。

108.Lost in translation: Molecular basis of reduced flower coloration in a self-pollinated monkeyflower (Mimulus) species.

在翻譯中丟失：?自花授粉的猴子花（Mimulus）物種花色減少的分子基礎(chǔ)。

109.Identification of immunomodulatory drugs that inhibit multiple inflammasomes and impair SARS-CoV-2 infection.

識(shí)別抑制多種炎癥體并損害SARS-CoV-2感染的免疫調(diào)節(jié)藥物。

110.Rapamycin treatment during development extends life span and health span of male mice and Daphnia magna.

發(fā)育期的雷帕霉素治療延長(zhǎng)了雄性小鼠和大型水蚤的壽命和健康期。

111.Ketogenic diet uncovers differential metabolic plasticity of brain cells.

生酮飲食揭示了腦細(xì)胞的不同代謝可塑性。

112.Targeting OXPHOS de novo purine synthesis as the nexus of FLT3 inhibitor–mediated synergistic antileukemic actions.

以O(shè)XPHOS新嘌呤合成為目標(biāo)，作為FLT3抑制劑介導(dǎo)的協(xié)同抗白血病作用的紐帶。

113.Exosome-mediated delivery of Cas9 ribonucleoprotein complexes for tissue-specific gene therapy of liver diseases.

外體介導(dǎo)的Cas9核糖核蛋白復(fù)合物在肝病組織特異性基因治療中的傳遞。

114.Molecular architecture of the autoinhibited kinesin-1 lambda particle.

自身抑制的驅(qū)動(dòng)蛋白-1 lambda粒子的分子結(jié)構(gòu)。

115.Oral zero-valent-molybdenum nanodots for inflammatory bowel disease therapy.

口服零價(jià)鉬納米點(diǎn)用于炎癥性腸病治療。

116.Deep learning reveals predictive sequence concepts within immune repertoires to immunotherapy.

深度學(xué)習(xí)揭示了免疫復(fù)合物中對(duì)免疫療法的預(yù)測(cè)序列概念。

117.Design of the SARS-CoV-2 RBD vaccine antigen improves neutralizing antibody response.

SARS-CoV-2 RBD疫苗抗原的設(shè)計(jì)提高了中和抗體反應(yīng)。

118.A self-generated Toddler gradient guides mesodermal cell migration.

自我生成的Toddler梯度引導(dǎo)中胚層細(xì)胞遷移。

119.Structural basis for FLCN RagC GAP activation in MiT-TFE substrate-selective mTORC1 regulation.

FLCN RagC GAP激活MiT-TFE底物選擇性mTORC1調(diào)節(jié)的結(jié)構(gòu)基礎(chǔ)。

120.A neurogenetic mechanism of experience-dependent suppression of aggression.

經(jīng)驗(yàn)依賴(lài)性抑制攻擊性的神經(jīng)遺傳機(jī)制。

121.Tandem pore domain acid-sensitive K channel 3 (TASK-3) regulates visual sensitivity in healthy and aging retina.

串聯(lián)孔域酸敏K通道3（TASK-3）調(diào)節(jié)健康和衰老視網(wǎng)膜的視覺(jué)敏感性。

122.Uncovering a tripartite landmark in posterior cingulate cortex.

揭開(kāi)后扣帶皮層的三方地標(biāo)。

123.Polarization vision mitigates visual noise from flickering light underwater.

偏振視覺(jué)減輕了水下閃爍光線的視覺(jué)噪音。

124.Socioeconomic resilience to climatic extremes in a freshwater fishery.

淡水漁業(yè)對(duì)極端氣候的社會(huì)經(jīng)濟(jì)復(fù)原力。

125.Biosignature stability in space enables their use for life detection on Mars.

太空中的生物特征穩(wěn)定性使其能夠用于火星上的生命探測(cè)。

126.Reduced plate motion controlled timing of Early Jurassic Karoo-Ferrar large igneous province volcanism.

板塊運(yùn)動(dòng)的減少控制了早侏羅紀(jì)卡魯-費(fèi)拉爾大火成巖省火山的時(shí)間。

127.Early tetrapod cranial evolution is characterized by increased complexity, constraint, and an offset from fin-limb evolution.

早期四足動(dòng)物顱骨演化的特點(diǎn)是復(fù)雜性增加，約束性增強(qiáng)，并與鰭肢演化相抵消。

128.Natural corrosion-induced gold nanoparticles yield purple color of Alhambra palaces decoration.

自然腐蝕誘導(dǎo)的金納米粒子產(chǎn)生了阿爾罕布拉宮裝飾的紫色。

129.Fast acquisition of propagating waves in humans with low-field MRI: Toward accessible MR elastography.

用低場(chǎng)核磁共振快速獲取人體的傳播波：邁向無(wú)障礙MR彈性成像。

130.Molecular beam homoepitaxy of N-polar AlN: Enabling role of aluminum-assisted surface cleaning.

N-極性AlN的分子束同質(zhì)化：鋁輔助的表面清潔的有利作用。

131.Design metastability in high-entropy alloys by tailoring unstable fault energies.

通過(guò)定制不穩(wěn)定的斷層能量來(lái)設(shè)計(jì)高熵合金的可轉(zhuǎn)移性。

132.Super-resolution wearable electrotactile rendering system.

超分辨率可穿戴式電觸覺(jué)渲染系統(tǒng).

133.Evolving symbolic density functionals.

符號(hào)密度函數(shù)的演化。

134.Ramped measurement technique for robust high-fidelity spin qubit readout.

穩(wěn)健的高保真自旋量子軌道讀出的斜率測(cè)量技術(shù)。

135.Unlocking the thermoelectric potential of the Ca14AlSb11 structure type.

挖掘Ca14AlSb11結(jié)構(gòu)類(lèi)型的熱電潛力。

136.Generation of stable microtubule superstructures by binding of peptide-fused tetrameric proteins to inside and outside.

通過(guò)多肽融合的四元蛋白內(nèi)外結(jié)合產(chǎn)生穩(wěn)定的微管超結(jié)構(gòu)。

137.Leakless end-to-end transport of small molecules through micron-length DNA nanochannels.

小分子通過(guò)微米長(zhǎng)的DNA納米通道的無(wú)泄漏端到端運(yùn)輸。

138.Making and breaking of chemical bonds in single nanoconfined molecules.

單個(gè)納米封閉分子中化學(xué)鍵的建立和斷裂。

139.High grain boundary recombination velocity in polycrystalline metal halide perovskites.

多晶體金屬鹵化物過(guò)氧化物中的高晶界重組速度。

140.Homoatomic cations: From [P5]+ to [P9]+.

同原子陽(yáng)離子：?從[P5]+到[P9]+。

141.Prospects of halide-based all-solid-state batteries: From material design to practical application.

鹵化物基全固態(tài)電池的前景：?從材料設(shè)計(jì)到實(shí)際應(yīng)用。

142.Demonstration of electric micropropulsion multimodality.

電動(dòng)微乳液多模態(tài)的演示。

143.Cooperative chemoenzymatic synthesis of N-heterocycles via synergizing bio- with organocatalysis.

通過(guò)生物與有機(jī)催化的協(xié)同作用合成N-雜環(huán)的化學(xué)酶法。

144.Mutations in BCOR, a co-repressor of CRX/OTX2, are associated with early-onset retinal degeneration.

BCOR是CRX/OTX2的共同抑制因子，其突變與早發(fā)的視網(wǎng)膜變性有關(guān)。

145.Pronounced sequence specificity of the TET enzyme catalytic domain guides its cellular function.

TET酶催化結(jié)構(gòu)域明顯的序列特異性指導(dǎo)其細(xì)胞功能。

146.MAIA, Fc receptor–like 3, supersedes JUNO as IZUMO1 receptor during human fertilization.

MAIA，F(xiàn)c受體樣3，在人類(lèi)受精過(guò)程中取代了JUNO作為IZUMO1受體。

147.Proteotype coevolution and quantitative diversity across 11 mammalian species.

11個(gè)哺乳動(dòng)物物種的蛋白型共同進(jìn)化和定量多樣性。

148.Heat selection enables highly scalable methylome profiling in cell-free DNA for noninvasive monitoring of cancer patients.

熱選擇使無(wú)細(xì)胞DNA中的高度可擴(kuò)展的甲基組分析用于對(duì)癌癥患者的非侵入性監(jiān)測(cè)。

149.Arabidopsis TIE1 and TIE2 transcriptional repressors dampen cytokinin response during root development.

擬南芥TIE1和TIE2轉(zhuǎn)錄抑制劑抑制了根系發(fā)育過(guò)程中的細(xì)胞因子反應(yīng)。

150.Distinctive exercise-induced inflammatory response and exerkine induction in skeletal muscle of people with type 2 diabetes.

2型糖尿病患者骨骼肌中獨(dú)特的運(yùn)動(dòng)誘發(fā)的炎癥反應(yīng)和外激素誘導(dǎo)。

151.The core PCP protein Prickle2 regulates axon number and AIS maturation by binding to AnkG and modulating microtubule bundling.

核心PCP蛋白Prickle2通過(guò)與AnkG結(jié)合和調(diào)控微管束來(lái)調(diào)節(jié)軸突數(shù)量和AIS成熟。

152.Transient RNA structures cause aberrant influenza virus replication and innate immune activation.

瞬時(shí)RNA結(jié)構(gòu)引起異常的流感病毒復(fù)制和先天免疫激活。

153.Two cooperative binding sites sensitize PI(4,5)P2 recognition by the tubby domain.

兩個(gè)合作的結(jié)合點(diǎn)使PI(4,5)P2被tubby結(jié)構(gòu)域識(shí)別變得敏感。

154.A two-step mechanism governing PARP1-DNA retention by PARP inhibitors.

PARP1-DNA被PARP抑制劑保留的兩步機(jī)制。

155.Coevolution of the Ess1-CTD axis in polar fungi suggests a role for phase separation in cold tolerance.

極地真菌中Ess1-CTD軸的共同進(jìn)化表明相分離在耐寒中的作用。

156.The spindle assembly checkpoint is a therapeutic vulnerability of CDK4/6 inhibitor–resistant ER+ breast cancer with mitotic aberrations.

紡錘體組裝檢查點(diǎn)是CDK4/6抑制劑耐藥的ER+乳腺癌有絲分裂畸變的治療弱點(diǎn)。

157.Pathogen effector AvrSr35 triggers Sr35 resistosome assembly via a direct recognition mechanism.

病原體效應(yīng)物AvrSr35通過(guò)直接識(shí)別機(jī)制引發(fā)Sr35抗性體組裝。

158.Nanotoxoid vaccination protects against opportunistic bacterial infections arising from immunodeficiency.

納米類(lèi)毒素疫苗接種可防止免疫缺陷引起的機(jī)會(huì)性細(xì)菌感染。

159.Variant Polycomb complexes in Drosophila consistent with ancient functional diversity.

果蠅中變異的Polycomb復(fù)合體與古代功能多樣性相一致。

160.When self comes to a wandering mind: Brain representations and dynamics of self-generated concepts in spontaneous thought.

當(dāng)自我來(lái)到一個(gè)游蕩的心：?自發(fā)思維中自我產(chǎn)生的概念的大腦表征和動(dòng)態(tài)。

161.Seasonal changes in day length induce multisynaptic neurotransmitter switching to regulate hypothalamic network activity and behavior.

晝長(zhǎng)的季節(jié)性變化誘發(fā)多突觸神經(jīng)遞質(zhì)切換，以調(diào)節(jié)下丘腦網(wǎng)絡(luò)活動(dòng)和行為。

162.Membrane tension propagation couples axon growth and collateral branching.

膜張力傳播與軸突生長(zhǎng)和側(cè)枝的耦合。

163.A red nucleus–VTA glutamate pathway underlies exercise reward and the therapeutic effect of exercise on cocaine use.

紅核-VTA谷氨酸通路是運(yùn)動(dòng)獎(jiǎng)勵(lì)和運(yùn)動(dòng)對(duì)可卡因使用的治療作用的基礎(chǔ)。

164.Encoding of social novelty by sparse GABAergic neural ensembles in the prelimbic cortex.

前大腦皮層稀疏的GABA能神經(jīng)群對(duì)社會(huì)新事物的編碼。

165.An extra-clock ultradian brain oscillator sustains circadian timekeeping.

一個(gè)時(shí)鐘外的超晝夜腦振蕩器維持了晝夜節(jié)律的計(jì)時(shí)。

166.Inheritance of somatic mutations by animal offspring.

動(dòng)物后代對(duì)體細(xì)胞變異的繼承。

167.Orthologous microsatellites, transposable elements, and DNA deletions correlate with generation time and body mass in neoavian birds.

正交微衛(wèi)星、可轉(zhuǎn)座元素和DNA缺失與新鳥(niǎo)類(lèi)的世代時(shí)間和體重相關(guān)。

168.Diamond formation kinetics in shock-compressed C─H─O samples recorded by small-angle x-ray scattering and x-ray diffraction.

通過(guò)小角度X射線散射和X射線衍射記錄沖擊壓縮的C─H─O樣品中鉆石的形成動(dòng)力學(xué)。

169.Mars Oxygen ISRU Experiment (MOXIE)—Preparing for human Mars exploration.

火星氧氣ISRU實(shí)驗(yàn)（MOXIE）--為人類(lèi)火星探測(cè)做準(zhǔn)備。

170.Hydroxide films on mica form charge-stabilized microphases that circumvent nucleation barriers.

云母上的氫氧化物薄膜形成電荷穩(wěn)定的微相，繞過(guò)成核障礙。

171.On-chip scalable highly pure and indistinguishable single-photon sources in ordered arrays: Path to quantum optical circuits.

在有序陣列中的片上可擴(kuò)展的高純度和無(wú)差別的單光子源：?通往量子光學(xué)電路的道路。

172.Enabling full-scale grain boundary mitigation in polycrystalline perovskite solids.

在多晶過(guò)氧化物固體中實(shí)現(xiàn)全面的晶界緩解。

173.Observation of competing, correlated ground states in the flat band of rhombohedral graphite.

觀察斜方體石墨平帶中相互競(jìng)爭(zhēng)、相互關(guān)聯(lián)的基態(tài)。

174.Tailoring electronic-ionic local environment for solid-state Li-O2 battery by engineering crystal structure.

通過(guò)工程晶體結(jié)構(gòu)為固態(tài)鋰-O2電池定制電子-離子局部環(huán)境。

175.Uncooled self-powered hemispherical biomimetic pit organ for mid- to long-infrared imaging.

用于中長(zhǎng)紅外成像的無(wú)冷卻自供電半球形仿生物坑器官。

176.A conserved molecular template underlies color pattern diversity in estrildid finches.

一個(gè)保守的分子模板支撐著雌性雀鳥(niǎo)的顏色模式多樣性。

177.Direct observation of the molecular mechanism underlying protein polymerization.

直接觀察蛋白質(zhì)聚合的分子機(jī)制。

178.Endothelial versus pronephron fate decision is modulated by the transcription factors Cloche/Npas4l, Tal1, and Lmo2.

轉(zhuǎn)錄因子Cloche/Npas4l、Tal1和Lmo2調(diào)節(jié)內(nèi)皮細(xì)胞與代償細(xì)胞的命運(yùn)決定。

179.Endogenous DOPA inhibits melanoma through suppression of CHRM1 signaling.

內(nèi)源性DOPA通過(guò)抑制CHRM1信號(hào)傳導(dǎo)抑制黑色素瘤。

180.An ex vivo culture model of kidney podocyte injury reveals mechanosensitive, synaptopodin-templating, sarcomere-like structures.

腎臟莢膜細(xì)胞損傷的體外培養(yǎng)模型揭示了機(jī)械敏感的、突觸蛋白誘導(dǎo)的、類(lèi)似肉體的結(jié)構(gòu)。

181.Spatiotemporal NF-κB dynamics encodes the position, amplitude, and duration of local immune inputs.

NF-κB的時(shí)空動(dòng)態(tài)編碼了局部免疫輸入的位置、振幅和持續(xù)時(shí)間。

182.scAllele: A versatile tool for the detection and analysis of variants in scRNA-seq.

scAllele：?用于檢測(cè)和分析scRNA-seq中變體的多功能工具。

183.Ventromedial hypothalamic OGT drives adipose tissue lipolysis and curbs obesity.

下丘腦內(nèi)側(cè)OGT驅(qū)動(dòng)脂肪組織的脂肪分解并抑制肥胖癥。

184.Altered epidermal proliferation, differentiation, and lipid composition: Novel key elements in the vitiligo puzzle.

表皮增殖、分化和脂質(zhì)成分的改變：白癜風(fēng)難題中的新的關(guān)鍵因素。

185.In vivo isotope tracing reveals a requirement for the electron transport chain in glucose and glutamine metabolism by tumors.

體內(nèi)同位素追蹤揭示了腫瘤在葡萄糖和谷氨酰胺代謝中對(duì)電子傳輸鏈的要求。

186.Phosphorylation of FAM134C by CK2 controls starvation-induced ER-phagy.

CK2對(duì)FAM134C的磷酸化控制饑餓誘導(dǎo)的ER-吞噬作用。

187.Structural insights into crista junction formation by the Mic60-Mic19 complex.

對(duì)Mic60-Mic19復(fù)合物形成的嵴椎結(jié)的結(jié)構(gòu)見(jiàn)解。

188.Structure of the vasopressin hormone–V2 receptor–β-arrestin1 ternary complex.

血管加壓素荷爾蒙-V2受體-β-arrestin1三元復(fù)合物的結(jié)構(gòu)。

189.Genome-wide in vivo screen of circulating tumor cells identifies SLIT2 as a regulator of metastasis.

循環(huán)腫瘤細(xì)胞的全基因組體內(nèi)篩選發(fā)現(xiàn)SLIT2是轉(zhuǎn)移的調(diào)節(jié)因子。

190.JAG1-NOTCH4 mechanosensing drives atherosclerosis.

JAG1-NOTCH4機(jī)械感應(yīng)驅(qū)動(dòng)動(dòng)脈粥樣硬化。

191.A lysosomal regulatory circuit essential for the development and function of microglia.

對(duì)小膠質(zhì)細(xì)胞的發(fā)育和功能至關(guān)重要的溶酶體調(diào)節(jié)回路。

192.Metformin prevents age-associated ovarian fibrosis by modulating the immune landscape in female mice.

二甲雙胍通過(guò)調(diào)節(jié)雌性小鼠的免疫景觀來(lái)預(yù)防年齡相關(guān)的卵巢纖維化。

193.Base editor enables rational genome-scale functional screening for enhanced industrial phenotypes in Corynebacterium glutamicum.

基地編輯使合理的基因組規(guī)模功能篩選在谷氨酸桿菌中增強(qiáng)工業(yè)表型。

194.Structure and mechanism for streptococcal fatty acid kinase (Fak) system dedicated to host fatty acid scavenging.

專(zhuān)用于宿主脂肪酸清除的鏈球菌脂肪酸激酶（Fak）系統(tǒng)的結(jié)構(gòu)和機(jī)制。

195.Operation of a TCA cycle subnetwork in the mammalian nucleus.

哺乳動(dòng)物細(xì)胞核中TCA循環(huán)子網(wǎng)絡(luò)的運(yùn)作。

196.Evolution of a chordate-specific mechanism for myoblast fusion.

脊柱動(dòng)物特有的肌細(xì)胞融合機(jī)制的演變。