「小普日?qǐng)?bào)」2023年11月10日熱點(diǎn)速遞
? 關(guān)鍵詞 奧希替尼 納武利尤單抗 肉毒毒素 循環(huán)腫瘤 DNA測(cè)序 維布妥昔單抗 依庫(kù)珠單抗 呋喹替尼 非酒精性脂肪性肝炎 ?
#今日行業(yè)熱點(diǎn)#
①The New England Journal of Medicine:Osimertinib with or without Chemotherapy in EGFR-Mutated Advanced NSCLC 臨床試驗(yàn):第三代表皮生長(zhǎng)因子受體酪氨酸激酶抑制劑奧希替尼單藥或聯(lián)合化療用于EGFR突變晚期非小細(xì)胞肺癌(NSCLC) DOI: 10.1056/NEJMoa2306434
Osimertinib with or without Chemotherapy in EGFR-Mutated Advanced NSCLC | NEJM
②The New England Journal of Medicine:Nivolumab plus Gemcitabine–Cisplatin in Advanced Urothelial Carcinoma 臨床試驗(yàn):納武利尤單抗(Nivolumab)聯(lián)合鉑類(lèi)藥物用于晚期尿路上皮癌的Ⅲ期、多國(guó)、開(kāi)放標(biāo)簽試驗(yàn) DOI: 10.1056/NEJMoa2309863
Nivolumab plus Gemcitabine–Cisplatin in Advanced Urothelial Carcinoma | NEJM
③The New England Journal of Medicine:Trial of Botulinum Toxin for Isolated or Essential Head Tremor 臨床試驗(yàn):肉毒毒素用于孤立性或原發(fā)性頭部震顫的試驗(yàn):一項(xiàng)多中心、雙盲、隨機(jī)試驗(yàn) DOI: 10.1056/NEJMoa2304192
Trial of Botulinum Toxin for Isolated or Essential Head Tremor | NEJM
④Blood:Entirely noninvasive outcome prediction in central nervous system lymphomas using circulating tumor DNA 研究:超敏感的循環(huán)腫瘤(CT)DNA測(cè)序在中樞神經(jīng)系統(tǒng)淋巴瘤(CNSL)的作用 DOI: 10.1182/blood.2023022020
Entirely noninvasive outcome prediction in central nervous system lymphomas using circulating tumor DNA | Blood | American Society of Hematology (ashpublications.org)
⑤Blood:Brentuximab vedotin with dacarbazine or nivolumab as frontline cHL therapy in older patients ineligible for chemotherapy 臨床數(shù)據(jù):抗體偶聯(lián)藥物(ADC)維布妥昔單抗(Brentuximab vedotin)聯(lián)合達(dá)卡巴嗪或納武利尤單抗用于老年經(jīng)典型霍奇金淋巴瘤(cHL) DOI: 10.1182/blood.2022019536
Brentuximab vedotin with dacarbazine or nivolumab as frontline cHL therapy in older patients ineligible for chemotherapy | Blood | American Society of Hematology (ashpublications.org)
⑥Blood:Prospective Multi-Institutional Study of Eculizumab?to Treat High-Risk Stem Cell Transplant Associated TMA 依庫(kù)珠單抗(Eculizumab)用于高危干細(xì)胞移植相關(guān)血栓性微血管?。═MA)的前瞻性多機(jī)構(gòu)研究 DOI: 10.1182/blood.2023022526
Prospective Multi-Institutional Study of Eculizumab to Treat High-Risk Stem Cell Transplant Associated TMA | Blood | American Society of Hematology (ashpublications.org)
⑦VEGFR抑制劑呋喹替尼獲FDA批準(zhǔn)上市,用于既往使用過(guò)氟嘧啶、奧沙利鉑和伊立替康的轉(zhuǎn)移性結(jié)直腸癌 ⑧靶向CD47的SIRPαFc融合蛋白IMM01獲FDA授予孤兒藥資格,聯(lián)合阿扎胞甘用于慢性粒單核細(xì)胞白血?。–MML) ⑨CDK4選擇性抑制劑BGB-43395注冊(cè)一項(xiàng)Ⅰ期臨床試驗(yàn),擬評(píng)估單藥或聯(lián)合氟維司群或來(lái)曲唑用于HR+/HER 2-乳腺癌(BC)和其他晚期實(shí)體瘤 ⑩甲狀腺激素β受體(THR-β)選擇性激動(dòng)劑KH629獲FDA批準(zhǔn)開(kāi)展新藥研究,擬開(kāi)發(fā)用于非酒精性脂肪性肝炎(NASH) 科學(xué)探索的世界充滿(mǎn)挑戰(zhàn),AtaGenix致敬每一位拓荒者,更致力于成為您信賴(lài)的合作伙伴!