液相應(yīng)用解決方案-UPLC液相壓力波動(dòng)異常（規(guī)律性）
ACQUITY BSM 的壓力下降至零 - WKB12836
文章編號(hào): 12836點(diǎn)擊此處訪問(wèn)英文版本文章
故障描述
液流開啟時(shí)，初級(jí)泵的壓力有時(shí)會(huì)下降
壓力從 8000 psi 下降到 0 psi，然后再次升高
一個(gè)或多個(gè)溶劑管路或泵無(wú)液流
在疑似泵滲漏時(shí)可能會(huì)出現(xiàn)此問(wèn)題
環(huán)境
ACQUITYBSM
ACQUITY QSM
原因
流動(dòng)相儲(chǔ)液瓶中的流動(dòng)相耗盡或流動(dòng)相儲(chǔ)液瓶中的溶劑不足，導(dǎo)致溶劑管路中進(jìn)入了空氣
解決方法
檢查流動(dòng)相儲(chǔ)液瓶的所有溶劑管路。
確保流動(dòng)相儲(chǔ)液瓶已裝滿，足以完全浸沒(méi)溶劑管路末端的過(guò)濾頭/沉子。
如果使用緩沖液，請(qǐng)將管路置于 100％ 水中。
灌注各管路 5 min，確保緩沖液被沖洗出來(lái)。
將所有溶劑管路放在 100% 甲醇中。
灌注所有溶劑管路 5-10 min，或者直至所有氣泡消失。
以 100％ 甲醇開啟液流，并監(jiān)測(cè)壓力表以確認(rèn)壓力穩(wěn)定。
切換為正在使用的流動(dòng)相。
再次灌注各管路 5 min，以確保甲醇被沖洗出來(lái)。
開啟液流并監(jiān)測(cè)壓力表，確認(rèn)壓力穩(wěn)定。
Pressure drops to zero on ACQUITY BSM - WKB12836
Article number: 12836
SYMPTOMS
During flow, primary pump?shows sporadic pressure drops
Pressure drops from 8000 psi to 0 psi, and then rises again
No flow from one or more solvent lines or pumps
May appear as if the pump is leaking
ENVIRONMENT
ACQUITY?BSM
ACQUITY QSM
CAUSE
Air in the solvent lines?as a result of empty mobile phase bottles, or there is not enough solvent in mobile phase bottle
FIX or WORKAROUND
Check the mobile phase bottles for all solvent lines.
Ensure that?the mobile phase bottle is full enough to completely cover the filter/sinker at the end of the solvent line.
If buffer is used, place the lines in 100% water.
Prime each line for 5 minutes, to ensure that the buffer is washed out.
Place all solvent lines in 100% methanol.
Prime all solvent lines for 5-10 minutes, or until any air bubbles dissipate.
Start?a flow with 100% methanol and?monitor the?pressure charts to confirm steady pressure.
Switch to the?mobile phase in use.
Prime each line again for 5 minutes, to ensure that the methanol is washed out.
Start a flow and?monitor the?pressure charts?to confirm?steady pressure.
Alliance 2695 上的初級(jí)泵柱塞輸送期間突然出現(xiàn)壓力急劇下降 - WKB63811
故障描述
Alliance 2695 上的一臺(tái)傳動(dòng)裝置在柱塞輸送期間出現(xiàn)壓力急劇下降
下降 2 - 3 秒后，壓力恢復(fù)到正常水平
環(huán)境
2695 分離單元
原因
初級(jí)泵柱塞和正面密封件上發(fā)生鹽沉積
解決方法
拆下泵頭，檢查是否發(fā)生鹽沉積。
用水沖洗柱塞和密封件以去除鹽沉積，然后重新安裝泵頭。
附加信息
其他：
清洗單向閥門
Sudden, sharp pressure drop during primary plunger stroke on Alliance 2695 - WKB63811
Article number: 63811
SYMPTOMS
Sharp pressure drop during plunger stroke of one actuator on Alliance 2695
2-3 seconds after pressure drop, pressure rebuilds to normal level
ENVIRONMENT
2695 Separations Module
CAUSE
Salt buildup on the primary plunger and face seals
FIX or WORKAROUND
Remove the pump head and inspect for salt buildup.
Rinse the plunger and seals with water to remove salt, and then reinstall the pump head.
Replace the seals if necessary
ADDITIONAL INFORMATION
ACQUITY H-Class QSM 出現(xiàn)壓力波動(dòng) - WKB19400
故障描述
蓄積泵和系統(tǒng)壓力跡線出現(xiàn)壓力波動(dòng)
波動(dòng)仍處于系統(tǒng)壓力的 1% 范圍內(nèi)，但高于平時(shí)且不穩(wěn)定
可能會(huì)增加 UV 檢測(cè)器的基線噪音
動(dòng)態(tài)滲漏測(cè)試通過(guò)
更換單向閥無(wú)法解決問(wèn)題
環(huán)境
ACQUITY H-Class 四元溶劑管理器 (QSM)
原因
梯度比例閥 (GPV) 堵塞。
影響 A/B 溶劑管路或 C/D 溶劑管路
從 ACQUITY 控制臺(tái)關(guān)閉 GPV 時(shí)，一些溶劑仍然流經(jīng)受影響的管路
解決方法
更換受影響溶劑管路的雙通道 GPV (700005161)。
附加信息
Pressure fluctuations on ACQUITY H-Class QSM - WKB19400
Article number: 19400
SYMPTOMS
Pressure fluctuates on both Accumulator and System pressure traces
Delta still within 1% of system pressure but higher than usual and unstable
Can increase baseline noise on UV detectors
Dynamic leak test passes
Replacing check valves doesn't solve the problem
ENVIRONMENT
ACQUITY H-Class Quaternary Solvent Manager (QSM)
CAUSE
Blockage in gradient proportioning valve (GPV).
Affects either A/B solvent lines or C/D solvent lines
When closing GPV from Acquity Console, some solvent is still flowing through the affected line
FIX or WORKAROUND
Replace the dual-channel GPV (700005161) for the affected solvent lines.
