活性氧N-acetyl-L-Cysteine amide,CAS No. 38520-57-9
產品名稱:活性氧N-acetyl-L-Cysteine amide,CAS No. 38520-57-9
產地:西安
規(guī)格:1mg 5mg 10mg
純度:99%
用途:僅用于科研
狀態(tài):固體/粉末
儲藏條件:冷藏-20℃
溫馨提示:僅用于科研,不能用于人體實驗!
說明:提供使用說明,核磁圖譜,包裝,價格,產地,制備方法,應用,穩(wěn)定性,溶解度,簡單合成等各種信息
N-acetyl-L-Cysteine amide (NACA) is an antioxidant.It is the amide form of N-acetyl-L-cysteine?and has increased cellular membrane and blood-brain barrier permeability compared to NAC. NACA (750 μM) inhibits glutamate-induced cytotoxicity, decreases in intracellular glutathione (GSH) levels, and increases in intracellular reactive oxygen species (ROS) levels in PC12 cells.It reduces cortical tissue damage and decreases the distance traveled to the platform in the Morris water maze in a rat model of traumatic brain injury.NACA (60 and 120 mg/kg) also inhibits ovalbumin-induced decreases in GSH, increases in nuclear NF-κB p65 and HIF-1α, and increases in IL-4, IL-5, and IL-13 levels in mouse lung tissue.

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編輯:XAQYBIO HAO,2023年4月20日。