品牌：為華生物

產(chǎn)地：中國廣州

PEG分子量：2k、3.4k、5k

外觀：白色固體或液體，取決于分子量

常用溶劑：溶于大部分有機(jī)溶劑，溶于水

?

mPEG-NH2?是一種含有氨基的單官能甲氧基聚乙二醇衍生物之一。氨基與羧酸、活性酯等反應(yīng)，羧基和許多其他胺反應(yīng)性官能團(tuán)在水性緩沖液或有機(jī)溶劑中快速反應(yīng)。氨基官能PEG可用于通過其游離的伯胺基團(tuán)修飾蛋白質(zhì)，多肽，抗體，顆粒和其他材料，降低多肽和蛋白質(zhì)的免疫原性。

產(chǎn)品的氨基端，對于酰化試劑活性比羥基高，它很容易進(jìn)行還原氨基化反應(yīng)。應(yīng)用氨基的反應(yīng)活性，可以通過生成穩(wěn)定的化學(xué)鍵(如酰胺鍵，氨基甲酸酯鍵，脲鍵和仲胺鍵)，把另一些分子和其連接。它們可用于:制備帶有生物活性化合物的配體;多肽合成時的載體;制備高分子接枝物和PEG涂層;制備PEG糖蛋白配體。

Mpeg-nh2 is one of the monofunctional methoxy polyethylene glycol derivatives containing amino groups. The amino group reacts with carboxylic acid and active ester, and the carboxyl group and many other amine reactive functional groups react rapidly in aqueous buffer or organic solvent. Amino functional peg can be used to modify proteins, polypeptides, antibodies, particles and other materials through its free primary amine groups to reduce the immunogenicity of peptides and proteins.

The amino end of the product is more active than the hydroxyl group for acylation reagent, and it is easy to carry out reductive amination reaction. By using the reactive activity of amino groups, other molecules can be connected to them by generating stable chemical bonds (such as amide bond, carbamate bond, urea bond and secondary amine bond). They can be used to: prepare ligands with bioactive compounds; Carrier for polypeptide synthesis; Polymer grafts and PEG coatings were prepared; Peg glycoprotein ligands were prepared.

溫馨提示：為華生物提供的產(chǎn)品，僅供科研，禁止用于人體。