艾美捷抗人干擾素α單抗(MT1),靈敏且高特異性
IFN-α2
干擾素-α(IFN-α,也稱(chēng)為IFN-α、IFN-α、IFNA和干擾素-α)是一種I型干擾素。人類(lèi)有?13?種?IFN-α 亞型:IFN-α?1、2、4、5、6、7、8、10、13、14、16、17?和?21。與其他亞型一樣,干擾素-α2 (IFN-?α2,也稱(chēng)為IFN-α2、IFN-α2、IFNA2和干擾素α2)主要由病毒感染的細(xì)胞在感知到病毒DNA或RNA等危險(xiǎn)信號(hào)的存在后產(chǎn)生。因此,IFN-α2?與其受體的結(jié)合引發(fā)了抗病毒反應(yīng),但也顯示了抗腫瘤作用。作為第1個(gè)被發(fā)現(xiàn)的,IFN-α2?是研究比較廣泛的亞型,它已被用作對(duì)抗丙型肝炎病毒感染的細(xì)胞因子療法。
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艾美捷抗人干擾素α單抗(MT1)能夠在?ELISA?和?ELISpot?等免疫測(cè)定中靈敏且特異地檢測(cè)人?IFN-α(亞型?2)。

推薦?MT1?作為?ELISA?和?ELISpot?中的捕獲抗體與生物素化檢測(cè)抗體?MT2?結(jié)合使用。
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艾美捷抗人干擾素α單抗(MT1)相關(guān)研究:
3310-10-1000 ELISpot?偶聯(lián)物:鏈霉親和素-ALP 1 ml
3310-8-1000 ELISA?偶聯(lián)物:鏈霉親和素-ALP 1 ml
3310-9-1000 ELISA/ELISpot?偶聯(lián)物:Streptavidin-HRP 1 ml
3423-6-1000?抗人?IFN-α?mAb (MT2),生物素?1 mg
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艾美捷抗人干擾素α單抗(MT1)相關(guān)文獻(xiàn)參考:
Bijak, M., et al. (2017). Flavonolignans Inhibit IL1-β-Induced Cross-Talk between Blood Platelets and Leukocytes. Nutrients.
Chan, L. J., et al. (2017). An Evaluation of Optimal PEGylation Strategies for Maximizing the Lymphatic Exposure and Antiviral Activity of Interferon after Subcutaneous Administration. Biomacromolecules.
Hochmann, S., et al. (2018). Evaluation of modified Interferon alpha mRNA constructs for the treatment of non-melanoma skin cancer. Sci Rep.
Ingelsson, B., et al. (2018). Lymphocytes eject interferogenic mitochondrial DNA webs in response to CpG and non-CpG oligodeoxynucleotides of class C. Proceedings of the National Academy of Sciences of the United States of America.
Yadav, P., et al. (2018). Distribution of therapeutic proteins into thoracic lymph after intravenous administration is protein size-dependent and primarily occurs within the liver and mesentery. J Control Release.