Theralizumab | 906068-56-2 - MedChemExpress
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Theralizumab
品牌:MedChemExpress (MCE)
Drug_Names:Theralizumab
CAS:906068-56-2
產(chǎn)品活性:Theralizumab (TGN1412) 是一種超級激動劑抗 CD28 單克隆抗體,可直接刺激 T 細胞。Theralizumab 可用于類風(fēng)濕性關(guān)節(jié)炎的研究[1][2]。
存儲條件:Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性: Theralizumab (TGN1412) 是一種超激動劑抗CD28 單克隆抗體,可直接刺激 T 細胞。 Theralizumab可用于類風(fēng)濕性關(guān)節(jié)炎的研究[1][2]。
參考文獻:
Thomas Hünig. The rise and fall of the CD28 superagonist TGN1412 and its return as TAB08: a personal account. FEBS J. 2016 Sep;283(18):3325-34.
Dmitry Tyrsin, et al. From TGN1412 to TAB08: the return of CD28 superagonist therapy to clinical development for the treatment of rheumatoid arthritis. Clin Exp Rheumatol. Jul-Aug 2016;34(4 Suppl 98):45-8.