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Thalamic reticular nucleus

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Thalamic reticular nucleus

?

Thalamus

Details

Part of

Thalamus

Identifiers

Latin

nucleus reticularis thalami

NeuroNames

365

NeuroLex?ID

birnlex_1721

TA98

A14.1.08.638

TA2

5704

FMA

62026

Anatomical terms of neuroanatomy

[edit on Wikidata]

The?thalamic reticular nucleus?is part of the ventral thalamus?

（說明thalamic reticular?nucleus很有可能只影響lateral ventral thalamus--VA, VL, VI, VPL, VPM。）

that forms a capsule around the?thalamus?laterally. However, recent evidence from mice and fish question this statement and define it as a dorsal thalamic structure.[1][2]?It is separated from the thalamus by the?external medullary lamina. Reticular cells are?GABAergic, and have discoid dendritic arbors in the plane of the nucleus.

Thalamic Reticular Nucleus is variously abbreviated TRN, RTN, NRT, and RT.

Contents

·?1Input and output

·?2References

·?3Further reading

·?4External links

Input and output[edit]

The thalamic reticular nucleus receives input from the?cerebral cortex?and dorsal thalamic nuclei. Most input comes from collaterals of fibers passing through the thalamic reticular nucleus. Primary thalamic reticular nucleus efferent fibers project to dorsal thalamic nuclei, but never to the cerebral cortex. This is the only thalamic nucleus that does not project to the cerebral cortex, instead it modulates the information from other nuclei in the thalamus. Its function is modulatory on signals going through thalamus (and the reticular nucleus).

The thalamic reticular nucleus receives massive projections from the external segment of the Globus Pallidus

（這一句話就與basal ganglia扯上聯(lián)系了，這樣我就又可以研究thalamic reticular nucleus,事實上我也得到了一些與其相關(guān)的推理。這個詞條中其他的內(nèi)容基本都是表述模糊的廢話。the external segment of the Globus Pallidus對thalamic reticular nucleus起到抑制作用，而serotonin在某種意義上也起到降低thalamic reticular nucleus敏感性的效果，而NE濃度高當(dāng)然就是加強其敏感性，增強抑制丘腦的效果。在NE作用下，丘腦的輸出減少，從而減少對amygdala的輸入，從而拉低NE放大環(huán)路，降低NE濃度。這一推理所對應(yīng)的行為效果十分重要，對應(yīng)著回避行為，和一類特殊的不愿回憶的記憶類型?；乇苄袨槭窍乱庾R的，無事先計劃的，而這種下意識回避行為可以被自己學(xué)到，因為發(fā)現(xiàn)逃跑的好處，從而回避行為的發(fā)生轉(zhuǎn)移到basal ganglia，從而形成主動有計劃的逃跑，二者產(chǎn)生的回避效果一樣，但是basal ganglia主導(dǎo)的主動有計劃的逃跑是在DA system狀態(tài)下完成的，NE濃度很低，與thalamic reticular nucleus主導(dǎo)的高NE濃度狀態(tài)下回避行為有本質(zhì)區(qū)別，二者的的許多附帶行為也不一樣，也就是說你想裝落荒逃跑的樣子還是很容易被識破的。對了，thalamic reticular nucleus主導(dǎo)的高NE濃度狀態(tài)下回避行為的持續(xù)時間很短，不會長時間維持，你所看到的動物受驚逃跑的距離其實都很短，長途轉(zhuǎn)移逃跑那都是有目的的basal ganglia行為，畢竟離危險越來越遠的過程也會感受到快樂，basal ganglia主導(dǎo)的持續(xù)行為就是好行為的不斷重復(fù)，哈哈，別忘了external segment of the Globus Pallidus就是在caudate nucleus的控制之下，而caudate nucleus在DA system的直接控制之下，這樣一來，basal ganglia主導(dǎo)的持續(xù)行為也對thalamic reticular nucleus進行抑制。對了，人的瞬間閃避行為就是高NE濃度下thalamic reticular nucleus活動的杰作。以上內(nèi)容均超出現(xiàn)在科學(xué)家的認知，因為他們沒有搞清楚serotonin和NE放大環(huán)路的規(guī)律，他們沒有搞清楚basal ganglia的運作機制，所以就算他們搞清楚了thalamic reticular nucleus的結(jié)構(gòu)和連接關(guān)系，他們依然認識不到“thalamic reticular nucleus是回避行為的本質(zhì)”。既然與thalamic reticular nucleus功能相關(guān)的行為找到了，接下來我的任務(wù)就是要在thalamic reticular nucleus的結(jié)構(gòu)和連接關(guān)系基礎(chǔ)上，分析出回避行為的細胞層面的機制。）

, thought to play a part in disinhibition of thalamic cells, which is essential for initiation of movement (Parent and Hazrati, 1995)

It has been suggested that the reticular nucleus receives afferent input from the?reticular formation[citation needed]?and in turn projects to the other thalamic nuclei, regulating the flow of information through these to the cortex. There is debate over the presence of distinct sectors within the nucleus that each correspond to a different sensory or cognitive modality.

For original connectivity anatomy see Jones 1975.[3]

For discussion of mapping and cross modality pathways see Crabtree 2002.[4]