活性氧Phenethyl isothiocyanate,CAS No. 2257-09-2
產(chǎn)品名稱:活性氧Phenethyl isothiocyanate,CAS No. 2257-09-2
產(chǎn)地:西安
規(guī)格:1mg 5mg 10mg
純度:99%
用途:僅用于科研
狀態(tài):固體/粉末
儲(chǔ)藏條件:冷藏-20℃
溫馨提示:僅用于科研,不能用于人體實(shí)驗(yàn)!
說明:提供使用說明,核磁圖譜,包裝,價(jià)格,產(chǎn)地,制備方法,應(yīng)用,穩(wěn)定性,溶解度,簡單合成等各種信息
Phenethyl isothiocyanate (PEITC) is an isothiocyanate that has been found in cruciferous vegetables and has anticancer activity.It inhibits the activity of glutathione peroxidase (GPX), reduces cellular glutathione (GSH) levels, and induces the accumulation of reactive oxygen species (ROS) in T72 ovarian epithelial cells expressing H-RasV12 when used at a concentration of 10 μM.2 PEITC (10 μM) induces cell cycle arrest at the G2/M phase and apoptosis in PL45, MIA PaCa-2, and BxPC-3 pancreatic cancer cells.?It decreases the number of tumor cells expressing Ki-67 or proliferating cell nuclear antigen (PCNA), markers of cell proliferation, and reduces tumor growth in a MIA PaCa-2 mouse xenograft model.

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編輯:XAQYBIO HAO,2023年4月20日。