【文獻速遞】【Nchem】【2022年】【7-12月】
聲明：本專欄主要對生命科學領域的一些期刊文章標題進行翻譯，所有內(nèi)容均由本人手工整理翻譯。由于本人專業(yè)為生物分析相關，其他領域如果出現(xiàn)翻譯錯誤請諒解。
自旋交叉的手性控制
The magnetic switching capabilities of transition-metal spin-crossover (SCO) complexes show potential as multifunctional switches for applications in information storage and processing. However, the photo-induced spin-crossover behaviour of Fe(II) complexes is not fully understood and thus not fully exploited. Now, using ultrafast circular dichroism spectroscopy, a symmetry-breaking twisting mode has been observed during the high-spin-state relaxation of FeII(4,4’-dimethyl-2,2’-bipyridine)3 — this molecule is shown on the cover undergoing photoexcitation. The relaxation of the high-spin state is also shown to be retarded through control of its configuration using enantiopure counterions.
過渡金屬自旋交叉（SCO）復合物的磁性開關能力顯示出作為信息存儲和處理應用的多功能開關的潛力。然而，F(xiàn)e(II)配合物的光致自旋交叉行為尚未完全了解，因此未得到充分利用?，F(xiàn)在，使用超快圓二色光譜，在FeII(4,4'-二甲基-2,2'-聯(lián)吡啶)3的高自旋態(tài)弛豫過程中觀察到了對稱破缺扭曲模式——該分子顯示在封面上進行光激發(fā)。通過使用對映體純抗衡離子控制其構型，也顯示出高自旋狀態(tài)的弛豫會延遲。
1.Chiral control of spin-crossover dynamics in Fe(II) complexes.
鐵(II)復合物中自旋交叉動力學的手性控制。
2.Ion-pair reorganization regulates reactivity in photoredox catalysts.
離子對重組調(diào)控光氧化催化劑的反應性。
3.Controlled masking and targeted release of redox-cycling ortho-quinones via a C–C bond-cleaving 1,6-elimination.
通過C-C鍵斷裂的1,6-消除法控制氧化還原循環(huán)正醌的掩蔽和定向釋放。
4.Prebiotic synthesis and triphosphorylation of 3′-amino-TNA nucleosides.
3′-氨基-TNA核苷的預生物合成和三磷酸化。
5.Condensates in RNA repeat sequences are heterogeneously organized and exhibit reptation dynamics.
RNA重復序列中的凝結(jié)物是異質(zhì)組織的，并表現(xiàn)出爬行動力學。
6.Accelerating symmetry-breaking charge separation in a perylenediimide trimer through a vibronically coherent dimer intermediate.
通過振子相干的二聚體中間物加速了苝二酰亞胺三聚體中的對稱性破壞電荷分離。
7.Stabilization of hexazine rings in potassium polynitride at high pressure.
高壓下多氮化鉀中己唑環(huán)的穩(wěn)定化。
8.Binding methane to a metal centre.
將甲烷與金屬中心結(jié)合。
9.An autonomously oscillating supramolecular self-replicator.
一個自主振蕩的超分子自我復制器。
10.Collisional excitation of HNC by He found to be stronger than for structural isomer HCN in experiments at the low temperatures of interstellar space.
在星際空間的低溫實驗中，發(fā)現(xiàn)He對HNC的碰撞激發(fā)比對結(jié)構異構體HCN更強。
11.Tunable acetylene sorption by flexible catenated metal–organic frameworks.
柔性連鎖的金屬有機框架對乙炔的可調(diào)控吸附。
12.Ultrafast proton-coupled isomerization in the phototransformation of phytochrome.
植物色素光轉(zhuǎn)化過程中的超快質(zhì)子耦合異構化。
13.O-GlcNAcylation modulates liquid–liquid phase separation of SynGAP/PSD-95.
O-糖基化調(diào)節(jié)SynGAP/PSD-95的液-液相分離。
平面的環(huán)對苯
Macrocycles made up of para-linked phenylene rings (the [n]CPPs) have attracted the attention of researchers because their unique conjugated structures result in interesting physical properties. Their strained topology makes it difficult to extend the aromatic system, but now a team led by Andreas G?rling, Konstantin Y. Amsharov and Sabine Maier have shown that a planar π-extended [12]CPP can be produced using a bottom-up on-surface synthesis approach. The resulting nanographene macrocycle, shown on the cover of this issue, features an all-armchair edge, which leads to delocalized electronic states around the entire ring.
由對位連接的亞苯基環(huán)（[n]CPP）組成的大環(huán)化合物引起了研究人員的注意，因為它們獨特的共軛結(jié)構導致了有趣的物理性質(zhì)。它們緊張的拓撲結(jié)構使得芳香系統(tǒng)難以擴展，但現(xiàn)在由Andreas G?rling、Konstantin Y. Amsharov 和 Sabine Maier領導的團隊表明，可以使用自下而上的表面上合成方法。由此產(chǎn)生的納米石墨烯大環(huán)，如本期封面所示，具有全扶手椅邊緣，導致整個環(huán)周圍的離域電子態(tài)。
1.Planar π-extended cycloparaphenylenes featuring an all-armchair edge topology.
以全臂椅邊緣拓撲結(jié)構為特征的平面π-擴展環(huán)芳烴。
2.Tunable and recyclable polyesters from CO2 and butadiene.
來自二氧化碳和丁二烯的可調(diào)整和可回收的聚酯。
3.Pathogenic bacteria remodel central metabolic enzyme to build a cyclopropanol warhead.
致病菌重塑中心代謝酶以建立環(huán)丙醇彈頭。
4.A two-directional vibrational probe reveals different electric field orientations in solution and an enzyme active site.
雙向振動探針揭示了溶液中不同的電場方向和一個酶活性部位。
5.Bifunctional sulfilimines enable synthesis of multiple N-heterocycles from alkenes.
雙功能磺酰亞胺能從烯烴中合成多種N-雜環(huán)化合物。
6.Photocaged 5′ cap analogues for optical control of mRNA translation in cells.
用于光學控制細胞內(nèi)mRNA翻譯的光籠5′帽類似物。
7.Deep learning study of tyrosine reveals that roaming can lead to photodamage.
對酪氨酸的深度學習研究揭示了漫游可導致光損傷。
8.Nickel-catalysed asymmetric hydrogenation of oximes.
鎳催化的肟類不對稱氫化作用。
9.Taming phosphorus mononitride.
馴服單氮化磷。
10.Low-temperature liquid platinum catalyst.
低溫液體鉑金催化劑。
11.A multi-stage single photochrome system for controlled photoswitching responses.
用于控制光開關反應的多級單光鉻系統(tǒng)。
12.Mechanism-based ligand design for copper-catalysed enantioconvergent C(sp3)–C(sp) cross-coupling of tertiary electrophiles with alkynes.
基于機制的配體設計，用于銅催化的三級電荷與炔烴的C（sp3）-C（sp）交叉耦合。
13.Functional DNA-based cytoskeletons for synthetic cells.
用于合成細胞的基于DNA的功能性細胞骨架。
植物到塑料變得甜美而簡單
Realizing sustainable plastics requires cost-effective production from renewable feedstocks, good materials properties and end-of-life recycling options. Now, a team led by Jeremy S. Luterbacher has taken advantage of the natural structure of sugars to create polymers that may meet these stringent criteria. Trapping the cyclic and oxygen-rich structure of carbohydrates (shown as a white chemical structure on the cover) within the backbone of these materials dramatically simplifies the production from nonedible biomass, leads to useful properties, enables closed-loop chemical recycling from mixed-plastic waste streams and provides a degradation route back to sugars in the presence of water. The 3D-printed leaf shown on the cover is made from this thermoplastic.
實現(xiàn)可持續(xù)塑料需要使用可再生原料進行具有成本效益的生產(chǎn)、良好的材料特性和報廢回收選擇?，F(xiàn)在，由Jeremy S. Luterbacher領導的團隊利用糖的天然結(jié)構來制造可能滿足這些嚴格標準的聚合物。將碳水化合物的環(huán)狀富氧結(jié)構（在封面上顯示為白色化學結(jié)構）捕獲在這些材料的主鏈內(nèi)，可顯著簡化非食用生物質(zhì)的生產(chǎn)，產(chǎn)生有用的特性，能夠從混合塑料廢物流中進行閉環(huán)化學回收，并在有水存在的情況下提供回到糖的降解途徑。封面上顯示的3D打印葉子就是用這種熱塑性塑料制成的。
1.Sustainable polyesters via direct functionalization of lignocellulosic sugars.
通過木質(zhì)纖維素糖的直接功能化實現(xiàn)可持續(xù)聚酯。
2.Mimicry of the proton wire mechanism of enzymes inside a supramolecular capsule enables β-selective O-glycosylations.
模仿超分子囊內(nèi)酶的質(zhì)子線機制，實現(xiàn)了β-選擇性的O-糖基化。
3.Functionalizing aromatic compounds with optical cycling centres.
用光學循環(huán)中心使芳香族化合物功能化。
4.Chemoenzymatic synthesis of fluorinated polyketides.
氟化聚酮類化合物的化學酶法合成。
5.Selective visible-light photocatalysis of acetylene to ethylene using a cobalt molecular catalyst and water as a proton source.
利用鈷分子催化劑和水作為質(zhì)子源，對乙炔制乙烯進行選擇性的可見光光催化。
6.A general design of caging-group-free photoactivatable fluorophores for live-cell nanoscopy.
用于活體細胞納米鏡的無籠罩基團的光活化熒光團的一般設計。
7.Conformational and functional changes of the native neuropeptide somatostatin occur in the presence of copper and amyloid-β.
在銅和淀粉樣物質(zhì)存在的情況下，本地神經(jīng)肽體蛋白的形態(tài)和功能發(fā)生了變化。
8.Time-resolved terahertz–Raman spectroscopy reveals that cations and anions distinctly modify intermolecular interactions of water.
時間分辨的太赫茲-拉曼光譜顯示，陽離子和陰離子明顯地改變了水的分子間相互作用。
9.Mechanically axially chiral catenanes and noncanonical mechanically axially chiral rotaxanes.
機械性軸向手性鏈烷烴和非經(jīng)典的機械性軸向手性輪烷。
10.Structure-specific amyloid precipitation in biofluids.
生物流體中結(jié)構特定的淀粉沉淀。
11.Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser.
X射線自由電子激光器捕捉到的編碼光觸發(fā)器的設計者蛋白質(zhì)中的激發(fā)態(tài)中間物。
12.Highly conducting single-molecule topological insulators based on mono- and di-radical cations.
基于單基和雙基陽離子的高導電性單分子拓撲絕緣體。
13.Exploiting the sp2 character of bicyclo[1.1.1]pentyl radicals in the transition-metal-free multi-component difunctionalization of [1.1.1]propellane.
利用雙環(huán)[1.1.1]戊基的sp2特性，對[1.1.1]丙二醇進行無過渡金屬的多組分雙功能化。
14.Light-activated tetrazines enable precision live-cell bioorthogonal chemistry.
光活化的四嗪類使精確的活細胞生物正交化學成為可能。
分子間庫侖衰變沒有界限
During intermolecular Coulombic decay (ICD), photoexcited molecules relax while ionizing their neighbouring molecules. This is usually observed in weakly bound systems — such as clusters and hydrogen-bonded systems — because ICD is efficient when intermolecular interactions are active. Now Sajeev, Aravind and colleagues have shown that ICD can occur between unbound pyridine molecules excited at ambient-light intensities, implying that soft ionization could occur naturally in astrophysical environments that feature such molecules with π-electron systems. The cover depicts this process occurring.
在分子間庫侖衰變（ICD）過程中，光激發(fā)分子在電離相鄰分子的同時松弛。這通常在弱結(jié)合系統(tǒng)（如團簇和氫鍵系統(tǒng)）中觀察到，因為當分子間相互作用活躍時，ICD是有效的?，F(xiàn)在，Sajeev、Aravind及其同事表明，ICD可以發(fā)生在在環(huán)境光強度下激發(fā)的未結(jié)合的吡啶分子之間，這意味著軟電離可以在具有π電子系統(tǒng)的此類分子的天體物理環(huán)境中自然發(fā)生。封面描述了這個過程的發(fā)生。
1.Ambient-light-induced intermolecular Coulombic decay in unbound pyridine monomers.
環(huán)境光誘導的非結(jié)合吡啶單體的分子間庫侖衰變。
2.In situ electrochemical recomposition of decomposed redox-active species in aqueous organic flow batteries.
水中有機流動電池中分解的氧化還原活性物種的原位電化學重組。
3.Phase-specific RNA accumulation and duplex thermodynamics in multiphase coacervate models for membraneless organelles.
無膜細胞器的多相共滲模型中的特定RNA積累和雙工熱力學。
4.Palladium-catalysed selective oxidative amination of olefins with Lewis basic amines.
鈀催化的烯烴與路易斯堿胺的選擇性氧化胺化。
5.Different timescales during ultrafast stilbene isomerization in the gas and liquid phases revealed using time-resolved photoelectron spectroscopy.
利用時間分辨光電子能譜技術揭示了氣相和液相中超高速鏈烷烴異構化的不同時間尺度。
6.Filling of a water-free void explains the allosteric regulation of the β1-adrenergic receptor by cholesterol.
無水空隙的填充解釋了膽固醇對β1-腎上腺素能受體的異生調(diào)節(jié)。
7.Prebiotic synthesis of α-amino acids and orotate from α-ketoacids potentiates transition to extant metabolic pathways.
來自α-酮酸的α-氨基酸和乳清酸的益生菌合成增強了向現(xiàn)存代謝途徑的過渡。
8.Synthesis of a low-valent Al4+ cluster cation salt.
低價Al4+簇狀陽離子鹽的合成。
9.σ–σ Stacked supramolecular junctions.
σ-σ堆積的超分子連接。
10.The ribosome stabilizes partially folded intermediates of a nascent multi-domain protein.
核糖體穩(wěn)定新生多域蛋白的部分折疊中間物。
11.Photochemical single-step synthesis of β-amino acid derivatives from alkenes and (hetero)arenes.
烯類和（雜）烯類的光化學單步合成β-氨基酸衍生物。
12.Palladium-catalysed construction of butafulvenes.
鈀催化構建丁香烯。
13.Genome-based discovery and total synthesis of janustatins, potent cytotoxins from a plant-associated bacterium.
基于基因組的Janustatins的發(fā)現(xiàn)和全合成，這是一種來自植物相關細菌的強效細胞毒素。
Topologically interesting cyclic polymers can be prepared by metathesis polymerization, but their precise synthesis has suffered from the catalyst’s vulnerability and inseparability. Now, Tae-Lim Choi and colleagues have designed a silica-supported ruthenium catalyst to overcome these limitations. With the help of customized glassware (a cyclic polymer dispenser), the use of this quarantined catalyst enables a continuous circular process of in situ polymerization, polymer separation, and catalyst recovery, giving a scalable process for the synthesis of cyclic polycyclopentene. The cover shows cyclopentene monomers undergoing ring-expansion metathesis polymerization to form cyclic polymers.
拓撲有趣的環(huán)狀聚合物可以通過易位聚合制備，但它們的精確合成受到催化劑的脆弱性和不可分離性的影響?，F(xiàn)在，Tae-Lim Choi及其同事設計了一種二氧化硅負載的釕催化劑來克服這些限制。在定制玻璃器皿（環(huán)狀聚合物分配器）的幫助下，使用這種隔離催化劑可以實現(xiàn)原位聚合、聚合物分離和催化劑回收的連續(xù)循環(huán)過程，從而為環(huán)狀聚環(huán)戊烯的合成提供可擴展的過程。封面展示了環(huán)戊烯單體正在經(jīng)歷擴環(huán)復分解聚合形成環(huán)狀聚合物。
1.Standardized excitable elements for scalable engineering of far-from-equilibrium chemical networks.
遠離平衡化學網(wǎng)絡的可擴展工程的標準化可激發(fā)元素。
2.Structure, reactivity and catalytic properties of manganese-hydride amidate complexes.
錳-氫酰胺復合物的結(jié)構、反應性和催化特性。
3.Scalable and continuous access to pure cyclic polymers enabled by ‘quarantined’ heterogeneous catalysts.
通過"隔離的"異質(zhì)催化劑實現(xiàn)純環(huán)狀聚合物的可擴展和連續(xù)訪問。
4.Photoinduced inverse vulcanization.
光誘導反硫化物。
5.Nanopore microscope identifies RNA isoforms with structural colours.
納米孔顯微鏡識別具有結(jié)構色彩的RNA異構體。
6.Lewis acid-assisted reduction of nitrite to nitric and nitrous oxides via the elusive nitrite radical dianion.
劉易斯酸輔助下的亞硝酸鹽通過難以捉摸的亞硝酸鹽自由基二元體還原為硝酸和亞硝酸。
7.Total synthesis of structurally diverse pleuromutilin antibiotics.
結(jié)構多樣的胸腺素抗生素的全合成。
8.Molecular interactions of FG nucleoporin repeats at high resolution.
高分辨率的FG核孔蛋白重復序列的分子相互作用。
9.Excitation energy transfer and vibronic coherence in intact phycobilisomes.
完整的植物蛋白體中的激發(fā)能量轉(zhuǎn)移和光子相干。
10.A modular XNAzyme cleaves long, structured RNAs under physiological conditions and enables allele-specific gene silencing.
一種模塊化的XNA酶在生理條件下裂解長的、結(jié)構化的RNA，并使等位基因特異性沉默。
11.Inverse hydride shuttle catalysis enables the stereoselective one-step synthesis of complex frameworks.
逆向氫化物穿梭催化使復雜框架的立體選擇性單步合成成為可能。
12.An autonomous portable platform for universal chemical synthesis.
一個用于通用化學合成的自主便攜式平臺。
13.Formation of a super-dense hydrogen monolayer on mesoporous silica.
中孔硅石上超密氫氣單層的形成。
14.Biosynthesis and characterization of fuscimiditide, an aspartimidylated graspetide.
夫西地肽的生物合成和特征，一種天冬酰亞胺糖肽。
難得一見的POMs
Radioisotopes can be very challenging to study because of their scarcity, rapid decay, toxicity or cost. Now, a team led by Gauthier J.-P. Deblonde has shown that only microgram quantities of these isotopes are required to generate radioisotope–polyoxometalate (POM) complexes that can be both spectroscopically and structurally characterized. The image on the cover shows a photograph, taken under ultraviolet light irradiation, of single crystals in crystallography oil of complexes between the rare radioactive 248Cm isotope and polyoxotungstate ligands.
由于放射性同位素的稀缺性、快速衰變、毒性或成本，研究它們可能非常具有挑戰(zhàn)性?，F(xiàn)在，由Gauthier J.-P. Deblonde領導的團隊表明，僅需微克量的這些同位素即可生成放射性同位素-多金屬氧酸鹽（POM）復合物，這種復合物可以在光譜和結(jié)構上進行表征。封面圖片顯示了在紫外光照射下拍攝的稀有放射性248Cm同位素與多氧鎢配體之間的絡合物結(jié)晶油中的單晶照片。
1.Polyoxometalates as ligands to synthesize, isolate and characterize compounds of rare isotopes on the microgram scale.
以多氧金屬為配體，合成、分離和表征微克級稀有同位素化合物。
2.Aldehyde-catalysed carboxylate exchange in α-amino acids with isotopically labelled CO2.
用同位素標記的二氧化碳催化α-氨基酸中的羧酸鹽交換。
3.Mass spectrometry captures biased signalling and allosteric modulation of a G-protein-coupled receptor.
質(zhì)譜法捕捉到G蛋白偶聯(lián)受體的偏向信號和變構調(diào)制。
4.Controlling anisotropic properties by manipulating the orientation of chiral small molecules.
通過操縱手性小分子的方向來控制各向異性的特性。
5.Biosynthesis-guided discovery reveals enteropeptins as alternative sactipeptides containing N-methylornithine.
生物合成引導下的發(fā)現(xiàn)揭示了腸肽是含有N-甲基鳥氨酸的替代性活性肽。
6.Recyclable and malleable thermosets enabled by activating dormant dynamic linkages.
通過激活休眠的動態(tài)鏈接實現(xiàn)可回收和可塑的熱固性材料。
7.Intersystem crossing in the entrance channel of the reaction of O(3P) with pyridine.
O(3P)與吡啶反應的入口通道中的系統(tǒng)間交叉。
8.Post-translational backbone-acyl shift yields natural product-like peptides bearing hydroxyhydrocarbon units.
翻譯后的骨架-?；D(zhuǎn)移產(chǎn)生了含有羥基烴單元的天然產(chǎn)品樣肽。
9.Practical synthesis of the therapeutic leads tigilanol tiglate and its analogues.
治療性替吉蘭醇及其類似物的實用合成。
10.Machine learning overcomes human bias in the discovery of self-assembling peptides.
機器學習克服了人類在發(fā)現(xiàn)自組裝肽方面的偏見。
11.Bending a photonic wire into a ring.
將光子線彎曲成環(huán)狀。
12.Synthesis and single-molecule imaging reveal stereospecific enhancement of binding kinetics by the antitumour eEF1A antagonist SR-A3.
合成和單分子成像揭示了抗腫瘤eEF1A拮抗劑SR-A3的結(jié)合動力學的立體特異性增強。
13.Circumventing the stability problems of graphene nanoribbon zigzag edges.
規(guī)避石墨烯納米帶之字形邊緣的穩(wěn)定性問題。
14.Diastereo- and enantioselective synthesis of compounds with a trifluoromethyl- and fluoro-substituted carbon centre.
具有三氟甲基和氟替代碳中心的化合物的非對映和對映選擇性合成。
