Osthole(蛇床子素)是一種抑制組胺 H1 受體 (histamine H1 receptor) 活性。傳統(tǒng)中藥 蛇床子的有效成分，具有抗炎、鎮(zhèn)痛、降脂等作用。在鵪鶉模型中顯著降低脂質(zhì)蓄積。它對(duì)MPP（+）誘導(dǎo)的PC12細(xì)胞中細(xì)胞毒性的神經(jīng)保護(hù)作用支持使用蛇床子素作為治療神經(jīng)退行性疾病的治療劑。在 HER2 過(guò)度表達(dá)的乳腺癌細(xì)胞中抑制脂肪酸合成酶的表達(dá)表明蛇床子素有望成為化療藥物。

案例：

Osthole ameliorates tumorigenesis of MG63 cells in vivo. (A) Photograph showing excised tumors in representative mice in each group implanted with MG-63 cells on day 30 after treatment. (B) Graph showing growth inhibition of human tumor xenografts in nude mice treated with osthole. (C) Graph illustrating the excised tumor weight on day 30 after osthole treatment.?